Selective estrogen receptor modulators. (Featured CME Topic).

Featured CME topic:

Date of Original Release: May 1, 2003

Term of Approval: 1 Year * Credit Expires: May 1, 2004

Estimated Time for Completion: 1 Hour

The following section was designed for physicians in all specialties, especially those in primary care. The Southern Medical Association is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians. This CME activity was planned and produced in accordance with the ACCME Essentials. The Southern Medical Association designates this educational activity for a maximum of 1 hour in Category 1 credit toward the AMA Physician's Recognition Award. Each physician should claim only those hours of credit. that he/she actually spent in the activity. The Featured CME Topic is a CME activity developed and administered by the Southern Medical Association's Department of Education. To obtain Category 1 credit, follow the instructions at the end of the section.

Purpose and Objectives

SERMS (selective estrogen receptor modulators) are a heterogeneous group of compounds that are able to bind to the estrogen receptor and have "tissue specific" effects in that they function as estrogen agonists in some tissues and estrogen antagonists in other tissues. SERMS may provide the benefits of estrogen replacement therapy without the increased risks. After reading the following feature, clinicians will have an understanding of the complex biology of SERMS and their myriad effects on different tissues, as well as their mechanisms of action and the risks and benefits of their use.

Disclosure

In publishing this section in Southern Medical Journal, the Southern Medical Association recognizes educational needs of physicians in all specialties, especially those in primary care, for current information regarding selective estrogen receptor modulators. In this section, authors may have included discussions about drug interventions, whether approved or unapproved by the U.S. Food and Drug Administration. Therefore, it is incumbent on physicians reading this section to be aware of these factors in interpreting the contents and evaluating recommendations. Moreover, views of authors do not necessarily reflect the opinions of the Southern Medical Association. Every effort has been made to encourage the author to disclose any commercial relationships or personal benefit that may be associated with this section. If the author disclosed a relationship, it is indicated below. This disclosure in no way implies that the information presented is biased or of lesser quality, but allows participants to make informed judgments regarding program content.

Disclaimer

The primary purpose of this section in the Journal is education. Information presented and techniques discussed are intended to inform physicians of medical knowledge, clinical procedures, and experiences of physicians willing to share such information with colleagues. It is recognized that a diversity of professional opinions exists in the contemporary practice of medicine that influences the selection of methods and procedures. The views and approaches of authors are offered solely for educational purposes. The Southern Medical Association disclaims any and all liability for injury or other damages to any individual reading this section and for all claims that may result from the use of techniques and procedures presented in it.