Scil Technology to Present at Medtech Insight's Dallas, TX ``IN SPINE & ORTHOPEDICS: Strategic Partnering and Investing in Musculoskeletal Technology'' Conference.MARTINSRIED, Germany -- Scil Technology has announced that it will be a presenter at Medtech Insight's "IN SPINE & ORTHOPEDICS" Conference, taking place November 2-3, 2005 at The Westin Stonebriar Resort in North Dallas, TX. Scil Technology is a German biopharmaceutical company focused on the development of dental and orthopaedic tissue regeneration products based on a combination of growth factors and in vivo in vivo /in vi·vo/ (ve´vo) [L.] within the living body. in vi·vo adj. Within a living organism. in vivo adv. degradable de·grad·a·ble adj. That can be chemically degraded: degradable plastic wastes. de·grad biomaterials. At the conference, Irina Staatz-Granzer, MD of Scil Technology, will be presenting data concerning ST01, a regenerative bone substitute material for spinal fusion spinal fusion n. A surgical procedure in which vertebrae are joined. Also called spondylosyndesis. Spinal fusion , and also ST03a, the first of the Company's cartilage repair product candidates. ST01 is an artificial bone substitute material for lumbar, thoracic and cervical spinal fusion and related procedures. The product is based on a ceramic biomaterial coated with a recombinant human growth factor. The validated growth factor encourages the growth of bone to replace the synthetic biomaterial, which is gradually resorbed over time. Earlier this year ST01 established proof of concept in a preclinical study with highly favourable results. The cartilage repair projects are based on the highly specific cartilage growth factor (CD-RAP) and target traumatic (ST03a) and degenerative (ST03b, Osteoarthritis osteoarthritis or osteoarthrosis or degenerative joint disease Most common joint disorder, afflicting over 80% of those who reach age 70. It does not involve excessive inflammation and may have no symptoms, especially at first. ) cartilage defects. CD-RAP stimulates the matrix synthesis in primary chondrocytes and influences the action of BMP-2 and TGF-(beta)3 during mesenchymal stem cell Mesenchymal stem cells or MSCs are multipotent stem cells that can differentiate into a variety of cell types. Cell types that MSCs have been shown to differentiate into in vitro or in vivo include osteoblasts, chondrocytes, myocytes, adipocytes, and, as described lately, differentiation, supporting the chondrogenic phenotype while inhibiting osteogenic osteogenic /os·te·o·gen·ic/ (-jen´ik) derived from or composed of any tissue concerned in bone growth or repair. os·te·o·gen·ic or os·te·o·ge·net·ic adj. differentiation. Moreover, it is involved in the control of inflammatory cytokine Cytokine Any of a group of soluble proteins that are released by a cell to send messages which are delivered to the same cell (autocrine), an adjacent cell (paracrine), or a distant cell (endocrine). expression occurring in damaged cartilage. ST03a successfully completed a preclinical study demonstrating that the growth factor stimulates the repair of cartilage defects in adult animals and that it plays a critical role in the maintenance of cartilage tissue by preventing undesired ossification ossification /os·si·fi·ca·tion/ (os?i-fi-ka´shun) formation of or conversion into bone or a bony substance. ectopic ossification . Dr Irina Staatz-Granzer, Managing Director of Scil, commented: "We are looking forward to presenting on our orthopaedic product portfolio In Dallas to an audience of industry peers and experts in spinal orthopaedics." About Scil Technology GmbH Scil Technology is a private biopharmaceutical development company focused on dental and orthopaedic tissue regeneration with a particular emphasis on bone and cartilage repair. The Company's lead therapeutic candidates are based on recombinant, highly specific human growth factors. These are combined with biodegradable biomaterials to generate local application forms. Scil Technology's pipeline for dentistry includes products that are targeted at periodontal disease, dental implantology and maxillofacial maxillofacial /max·il·lo·fa·cial/ (-fa´sh'l) pertaining to the maxilla and the face. max·il·lo·fa·cial adj. Relating to or involving the maxilla and the face. surgery. Orthopaedic products are developed for spinal fusion, bone and cartilage lesions and osteoarthritis. Scil Technology has emerged from the Scil Group and is located in the biotechnology cluster in Martinsried, Germany. For more information please visit: http://www.scil.com About Medtech Insight Medtech Insight, a division of Windhover Information Inc., is the leading provider of business information and market intelligence for the medical technology marketplace. To register for the "IN SPINE & ORTHOPEDICS" conference or for more information on Medtech Insight, please call Kristy Grimes at (480) 985-9512, e-mail kristy@medtechinsight.com, or visit www.medtechinsight.com. |
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