Scientists identify genes behind increasingly common form of cancer.Byline: ANI Washington, Oct 14 (ANI): Two genes believed to play a role in the development of endometrial cancer Endometrial Cancer Definition Endometrial cancer develops when the cells that make up the inner lining of the uterus (the endometrium) become abnormal and grow uncontrollably. have been identified by researchers at the University of Gothenburg, Sweden. The discovery could lead to better diagnosis and treatment of this increasingly common form of cancer. Endometrial cancer is also known as uterine uterine /uter·ine/ (u´ter-in) pertaining to the uterus. u·ter·ine adj. Of, relating to, or in the region of the uterus. or womb cancer. Cancer is caused by genetic changes - mutations - in cells' DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. disrupting the normal regulation of growth. In her study, researcher Carola Hedberg from the Department of Cell and Molecular Biology Cell and Molecular Biology may refer to:
Her research focuses on genetic analyses of rats, and more specifically their chromosome 10. This chromosome is interesting because it is prone to deletion - the loss of genetic material - in connection with tumour formation. Hedberg has been able to show that one or more growth-suppressing genes are normally to be found in the middle of the chromosome where this loss of genetic material is greatest. The deletion of these genes eliminates their growth-regulating functions, and this is believed to contribute to the development of endometrial cancer. Information about specific genetic changes in rats as a model can be transposed trans·pose v. trans·posed, trans·pos·ing, trans·pos·es v.tr. 1. To reverse or transfer the order or place of; interchange. 2. to the equivalent form of cancer in humans. A knowledge of the genes involved in a particular form of cancer may therefore contribute to cancer care in the longer term through better diagnostic tools and new forms of treatment and preventive care Preventive care is a set of measures taken in advance of symptoms to prevent illness or injury. This type of care is best exemplified by routine physical examinations and immunizations. The emphasis is on preventing illnesses before they occur. See also
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