Sachs-Bloomberg Global Biotech Forum for Investing & Partnering 2004 Participant Profiles.Business/Biotechnology Writers BIOWIRE2K Global Biotech bi·o·tech n. Informal Biotechnology. biotech Noun short for biotechnology Noun 1. Investor Forum 2004 BOSTON--(BUSINESS WIRE)--March 17, 2004 The Sachs-Bloomberg Annual Global Biotech Forum for Investing & Partnering takes place April 1-2, 2004, at the Fairmont Fairmont, city (1990 pop. 20,210), seat of Marion co., N central W.Va., where the West Fork and Tygart rivers form the Monongahela; settled 1793 around Prickett's Fort (1774), inc. as Fairmont 1843. Copley Plaza The Fairmont Copley Plaza hotel (or Copley Plaza as it is colloquially known) is a four-star hotel in downtown Boston, Massachusetts. It was built in 1912 on St. James Avenue and defines the south side of Copley Square. The Copley Plaza Hotel opened in 1912. in Boston Boston, town, England Boston, town (1991 pop. 26,495), E central England, on the Witham River. Boston's fame as a port dates from the 13th cent., when it was a Hanseatic port trading wool and wine. Having recovered from a decline in the 18th and 19th cent. . For in-depth in-depth adj. Detailed; thorough: an in-depth study. in-depth Adjective detailed or thorough: an in-depth analysis information about the event, visit http://www.sachsforum.com/global4_fs.html. Below are profiles from Global Biotech Forum presenters. Breaking news releases are available at http://www.tradeshownews.com, Business Wire's trade show and conference news resource. Business Wire is the official news wire service for the Sachs-Bloomberg Global Biotech Forum for Investing & Partnering. Company: AnorMED Inc Ticker Symbol: AOM: TSX Media Contact: Elisabeth Whiting Phone: 604.532.4667 E-mail: ewhiting@anormed.com Company URL: www.anormed.com Press Kit URL: http://www.anormed.com/investors/package.cfm Product description: AnorMED's lead program on AMD3100, a stem cell mobilizer, is in three phase II trials for stem cell transplant in cancer patients and in preclinical studies for cardiac tissue repair. AnorMED is also developing novel HIV entry inhibitors: AMD070, an oral CXCR4 HIV entry inhibitor, in Phase I trials and oral CCR5 candidates in preclinical studies. The Company has licensed several other products at various stages of clinical development to corporate partners. Company description: AnorMED is a biopharmaceutical company focused on the development of small molecule therapeutics for the treatment of a variety of diseases including cancer and HIV. Company: atugen AG Media Contact: Thomas Christely Phone:+49 30 9489 2800 E-mail: christely@atugen.com Company URL: www.atugen.com Product description: --siRNA therapeutic candidates in Diabetes and Oncology --Pipeline of proprietary novel and functionally validated cancer targets --Largest set of KnockDown technologies (low toxic GeneBlocs antisense molecules, stabilized synthetic siRNA) --Superior delivery reagents transfecting almost all cell types (transfection rate greater than 95%) Company description: atugen AG is a technology leader in functional gene silencing. The company is based in Berlin, Germany, and currently has about 40 employees. atugen's in-house drug development programs mainly focus on the generation of novel siRNA therapeutics. Here, the company exploits its expertise in oligonucleotide delivery and its recently discovered, chemically-stabilized, proprietary siRNA structures. With its contract research business , the company offers its expertise in target validation and drug discovery to biopharmaceutical customers and partners through research alliances and on a fee-for-service basis. Company: Aureon Biosciences Corporation Media Contact: Jon Edelson Phone: 914 377-4000 E-mail: info@aureon.com Company URL: www.aureon.com Products: --Predictive tests for cancer care examining individual response to treatment (initially in the areas of prostate and breast cancer) --Tissue analysis for pharmaceutical companies to enable clinical trials and toxicology activities Aureon's products are based on its proprietary technology platform combining novel molecular, imaging and bio-informatic technologies. Company Description: Aureon is applying its proprietary "systems pathology" tissue analysis technology platform to develop predictive clinical tests for cancer care as well as to enable bio-pharmaceutical research and development. Systems pathology integrates clinical, micro-anatomic, and molecular views of disease to provide new understandings of the disease itself as well as individual response to treatment. Company: BIOCORTECH Phone: +33 1 4568 8122 E-mail: contact@biocortech.com Company URL: www.biocortech.com Product description: --BC22 depression pre-clinical Biocortech develops innovative pharmaceutical compounds active on the central nervous system via two integrated proprietary platforms. --EDIT: quantification of 5HT2C and glutamate b receptor editing In vitro, in cellulo, ex vivo tests --TOP: quantification of the level of expression of specific proteins Ex vivo tests Company description: To treat neuropsychiatric disorders, Biocortech, localized at the Pasteur Institute (Paris) and in Cambridge (MA), develops new classes of psychotropic drugs efficient - on deep resistant depression by restoring deficient neural pathways - on bipolar depression, schizophrenia and cognitive impairment by modulating the editing mechanisms of serotonin and glutamate receptors. Company: CELLECTIS Media Contact: Andre Choulika Phone: 01 41 83 99 00 E-mail: choulika@cellectis.com Company URL: www.cellectis.com Press Kit URL: www.cellectis.com/news Product description: Cellectis was founded in 1999 as a spin-off from Institut Pasteur. It is the first Company to apply the Meganuclease Recombination System approach to in vivo genome engineering. Cellectis is focused on the research and development of novel Meganucleases for genome intervention and provides tools for site directed recombination in living organisms. Cellectis is committed to bring Genome Surgery to patients as a genuine new human therapeutic approach. Company description: The Company is developing Meganucleases that can target a unique DNA break in vivo, a fundamentally enabling technology for commercial applications as human therapeutics approach for genetic and infections diseases, pharmaceutical discovery, agriculture and industrial biotechnology. Cellectis' team today consists of 34 people including 14 PhDs and the total invested capital since the Company's inception is over USD 20 million. As of today, Cellectis has entered into more than 24 deals on its Genome Engineering technologies including Pharmaceutical and Global Companies. Company: Chronogen Inc Media Contact: Marie-Lise Gauthier Phone: 514-521-9595 ext 206 E-mail: mlgauthier@chronogen-inc.com Company URL: www.chronogen-inc.com Company description: Chronogen Inc., a privately-held drug discovery company, is a leader in the identification of targets that control the degenerative processes of aging. Based on this innovative approach, the company is developing novel products to control lipid and oxidative stress levels, which are established disease mechanisms in cardiovascular disorders. The control of aging in whole model organisms, worms and mice, has provided very valuable assets for a drug discovery technology that will lead to novel and efficacious drugs in significant markets including atherosclerosis, vascular complications of diabetes, and ischemia/reperfusion injuries. Chronogen is headquartered in Montreal, Canada. Chronogen announced an initial closing of $17 million (CAN) in an ongoing series B financing in November 2003. This new round of financing closed as Chronogen continues to build its multidisciplinary team of scientists, expands its operations, and acquires technologies to complement its drug discovery programs. Company: CombinatoRx, Inc. Media Contact: Daniel Grau Phone: 617 425 7000 E-mail: dgrau@combinatorx.com Company URL: www.combinatorx.com Product description: CombinatoRx has an impressive clinical and preclinical pipeline of novel agents, including treatments in development for cancer and rheumatoid arthritis, and has ongoing research in respiratory, metabolic, and infectious diseases. Company description: CombinatoRx is creating new combination medicines that attack disease on multiple fronts. CombinatoRx invented the industry's first combination drug discovery platform to generate new medicines, based upon new insights into disease networks, in a broad range of therapeutic areas. Founded in 2000 by scientists from Harvard and MIT, the company has raised $60M in venture capital and is executing on its business strategy to rapidly build and commercialize a portfolio of breakthrough products. Company: Concurrent Pharmaceuticals Media Contact: Richard Baxter Phone: 215.461.2000 E-mail: rbaxter@concurrentpharma.com Company URL: www.concurrentpharma.com Product description: Concurrent has created a portfolio of pre-clinical programs that are rapidly advancing into clinical development in hypertension, metabolic and respiratory disease, inflammation and Alzheimer's. In its hypertension program, Concurrent has identified novel, highly potent, selective and orally available renin inhibitors that tracking to plan for clinical development 2005. The hypertension market is expected to exceed $50 Billion in the next five years. Company description: Concurrent Pharmaceuticals, Inc. is a drug discovery and development company creating a portfolio of novel drug candidates for clinically significant diseases. The company has developed proprietary, computational drug design technology to accelerate the discovery of advanced orally active compounds. Its lead program is renin inhibitors for hypertension. Orally available compounds are currently in animal studies and are expected to enter the clinic in 2005. Company: ConjuGon, Inc. Media Contact: Salvatore Braico (608-441-2890) Investor Relations Contact: Christopher Price (703-608-3699) Phone: 1-608-441-2890 E-mail: info@conjugon.com Company URL: ww.conjugon.com Product description: ConjuGon is developing fundamentally new biotherapeutics to treat multi-drug-resistant bacterial infections. These biotherapeutics are based on a technology that uses harmless bacteria to introduce engineered genes into targeted bacteria. The genes are then expressed to form highly potent antibacterial products which proceed to kill the target through multiple, independent mechanisms. Company description: ConjuGon was founded in 2001 to develop and commercialize a novel antibacterial technology based on research done at the University of Wisconsin-Madison. The Company, led by an experienced team, has raised nearly $1.3 million in seed financing and is currently raising a $3.5 million Series A round. Company: Curis, Inc. Ticker Symbol: CRIS Media Contact: Marc Charette Investor Relations Contact: Michael Gray Phone: 617-503-6500 E-mail: mcharette@curis.com; mgray@curis.com Company URL: www.curis.com Product description: Our product development approach involves using small molecules, proteins or antibodies to modulate these regulatory signaling pathways. We have successfully developed several promising preclinical product candidates in the fields of kidney disease, cancer, neurological disorders, cardiovascular disease and hair growth regulation. Company description: Curis is a therapeutic drug development company principally focused on the discovery, development and future commercialization of products that modulate key regulatory signaling pathways controlling the repair and regeneration of human tissues and organs. We have a broad portfolio of product candidates and a diverse portfolio of corporate collaborations. Company: Cyclacel Limited Media Contact: Spiro Rombotis Investor Relations Contact: Paul McBarron Phone: +44 1382 206 062 E-mail: info@cyclacel.com Company URL: www.cyclacel.com Company description: Cyclacel - a biopharmaceutical company that designs and develops small molecule drugs that act on key cell cycle regulators to stop uncontrolled cell division in cancer and other diseases involving abnormal cell proliferation. The Company's discovery engines integrate cell cycle biology expertise with a large library of proprietary gene-based targets, state-of-the-art RNAi functional genomics, chemogenomics and clinical biomarker technologies to rapidly deliver new drugs. Nine research and development programs are underway. Most advanced is CYC202, a Cyclin Dependent Kinase (CDK) inhibitor, in Phase IIa trials. Corporate alliances in oncology entered into with AstraZeneca, CV Therapeutics, Lorus, Sankyo and top 5 pharmaceutical major. Company: Dermatrends, Inc. Media Contact: Joanne Henry (612) 843-2142 Phone: (612) 843-2142 E-mail: jhenry@henryschafer.com Company URL: www.dermatrends.com Product description: Dermatrends(R) offers licensing and joint development opportunities of its platform transdermal delivery technology. The company's patented enhancer system increases permeation to allow therapeutic delivery of many compounds not currently available in transdermal form. Our technology platform allow companies to extend drug patent life, while enabling transdermal delivery of compounds not well suited to oral delivery. Company Description: Dermatrends(R) has discovered a platform drug delivery technology that will dramatically change the face of transdermal drug delivery. Our in vitro tests and recent in vivo trials have demonstrated therapeutic delivery through the skin of more than 30 compounds. Our in vitro matrix patch tests include effective transdermal delivery of larger molecules, exceeding 1300 AMU, an industry breakthrough. Company: Ecopia BioSciences Inc. Ticker Symbol: EIA (on TSX) Media Contact: Karen Eugeni Phone: 514-336-2700 E-mail: eugeni@ecopiabio.com Company URL: www.ecopiabio.com Product description: Ecopia's drug discovery platform, DECIPHER(R) technology, has allowed us to identify compounds that have unique chemical diversity and often define new structural classes of drugs in the anticancer, antibacterial and antifungal markets. Of the five compounds discovered to date, two are advancing to preclinical trials and the Company expects to file an IND in 2005. Company description: Ecopia has built a pipeline of new anticancer, antibacterial and antifungal agents using its proprietary DECIPHER(R) technology. The Company's pipeline includes two anticancer agents, ECO-04601 and ECO-02201, an antibacterial agent, ECO-00501, and two antifungal agents, ECO-02301 and ECO-14401. Ecopia's shares are listed on the Toronto Stock Exchange (ticker symbol: EIA). Company: Eidogen, Inc. Media Contact: Janet Roberts (janet@gjroberts.com) Investor Relations Contact: Ted Kingsley Phone: (+011) 626-817-2200 Company URL: http://www.eidogen.com Product description: Eidogen's is the world's first structural and comparative proteomics enterprise software solution. TIP allows drug discovery researchers and organizations to attack their druggability, selectivity, toxicity, and reduced market exclusivity problems by supporting new and truly collaborative research in target prioritization, lead discovery, and lead optimization. Company description: Eidogen is a Pasadena, California based biotechnology company dedicated to delivering the finest computational drug discovery platforms ever developed. The last decade has seen the revolutionary human genome project transform the way our industry identifies drug targets. In the current decade, equally important revolutions in the fields of structural biology and computational chemistry will transform the way our industry performs target prioritization, lead identification, and lead optimization. Eidogen was established to lead this revolution. Company: Gene Express, Inc. Media Contact: Brad Leone, (419-893-9600) Investor Relations Contact: Jim Hodges, (847-234-1582) Company Phone: 419-380-9930 E-mail: jahodges@GeneExpressInc.com Company URL: www.GeneExpressInc.com Product description: Gene Express's revenues are generated by providing reagent sales and high margin multi-gene expression analysis services utilizing 700 assays at a high-throughput, Standardized Expression Measurement (SEM) Center to researchers in the U.S., Europe and Japan. Also, the company has developed four clinical, molecular, diagnostic tests for lung cancer. Company description: Gene Express, Inc. is a genomic biotech company that sells patented, quantitative, standardized, multi-gene expression platform technology (StaRT-PCR ) to academic institutions, pharmaceutical and biotech companies, the Departments of Defense and Homeland Security, and the food industry. Recently, the first project under a two-year agreement with Pfizer, Inc. was completed. Company: Generex Biotechnology Corporation Ticker Symbol: NasdaqSC: GNBT Investor Relations Contact: Todd Falls Phone: 416-364-2551 E-mail: info@generex.com Company URL: www.generex.com Product description: Oralin, Generex's most advanced product in development, is an oral insulin spray formulation for the treatment of Type-I and Type-II diabetes. Oralin is administered directly into the mouth as a metered-dose spray for rapid absorption by the buccal mucosa. Oralin is currently conducting Phase IIB clinical trials in North America. Company description: Generex Biotechnology Corporation is engaged in the research and development of drug delivery systems and technology. To date, Generex has focused on developing a platform technology for the buccal delivery of drugs that historically have been administered only by injection. RapidMist(TM) Generex's buccal drug delivery technology, has application to a large number of drugs. Company: GenOdyssee SA Media Contact: Jean-Louis Escary Phone: + 33 1 69 29 80 55 E-mail: escary@genodyssee.com Company URL: www.genodyssee.com Product description: Natural variants of human therapeutic proteins with higher therapeutic indices than reference products on the market. The lead virology candidate, GEA007.1, is a natural variant of human IFN-alpha that has demonstrated in vitro up to 100x higher antiviral activity (HCV replicon model) than marketed IFN alpha 2a or 2b for hepatitis treatment. GEA007.1, in particular, has been found with a better anti-HCV replication effect than IFN alpha 2b against HCV genotype 1b. This sustains results obtained in vitro in the VSV model, and in vivo with EMCV infected mice. The lead oncology candidate is GEA009.2, another variant of human IFN-alpha, that has demonstrated in vitro a stronger immune system stimulatory activity with less accompanying toxicity than the current marketed IFN 2b for cancer treatment. GEA009.2, has been found a more potent inducer of Natural Killer (NK) cells than IFN alpha 2, which confirms results obtained with previous ex vivo and in vivo immunological (FLC, P815, Dendritic cells) models. Company description: GenOdyssee (GO) is developing a series of compounds based on exploiting genetic mutations that confer super-therapeutic status on naturally produced therapeutic cytokines. While many companies are searching for deleterious genes and mutations responsible for disease pathology or susceptibility, GO, on the contrary, is developing therapeutics based on the assumption that natural genetic mutations derived from evolution can confer natural superiority to the pharmacological profiles of corresponding host human therapeutic genes, such as the genes that encode for blockbuster therapeutic cytokines IFN-alpha and EPO. Company: Genstruct, Inc. Media Contact: John Wilbanks Investor Relations Contact: Keith O. Elliston Phone: 617-547-5421 E-mail: info@genstruct.com Company URL: http://www.genstruct.com Product description: Genstruct, Inc., the leader in biological mechanism discovery, is developing therapeutics based on Molecular Epistemics(TM) an unprecedented approach to systems biology that leverages logical modeling and causal reasoning. Genstruct is building a therapeutic product pipeline and has successfully applied its platform to discover drug mechanisms of action and resistance. Company description: Genstruct is uniquely positioned to leverage the full potential of causal modeling for therapeutic discovery and improved clinical trial design. Genstruct's position as the first company to develop comprehensive, causal biological models is supported by patents, technology, and techniques relating to mechanism discovery and validated through world class collaborations. Company: HYBRIGENICS Media Contact: Dominique Granger Investor Relations Contact: Eric Cohen Phone:+ (33) 1 58 10 38 00 E-mail: ecohen@hybrigenics.com or pblondel@hybrigenics.com Company URL: http:/hybrigenics.com Press Kit URL: http:/hybrigeniccs.com/paged2_cad.htm Company description: Hybrigenics is a leader in Drug Discovery based on Functional Proteomics. Using innovative technology platforms, the Company identifies, selects and validates novel disease-associated targets in order to screen for small molecule drugs. Hybrigenics currently runs drug discovery programs in the fields of virology and oncology. Hybrigenics also collaborates with pharmaceutical companies in these and other therapeutic areas for joint research and product development. Company: Immunitor USA Inc. Media Contact: Dr. Aldar S. Bourinbaiar Phone: Tel: 66-9-244-6398 (Thailand) Tel: 1-301-474-9369 (USA) E-mail: info@immunitor.com Company URL: www.immunitor.com Product description: Four vaccines being manufactured to prevent or treat viral, bacterial, fungal infections; and cancer. Products are now marketed as food supplements. The lead product is in phase III clinical trial to be licensed as a therapeutic vaccine for AIDS wasting. Products in pipeline include oral vaccines for smallpox, hepatitis, and influenza. Company description: Immunitor USA Inc., is a joint venture with Immunitor Corporation - the first private biotech company in Thailand. The Company has exclusive rights to technology developed by Thai partner. This technology enables to formulate a vaccine as an oral pill. Company's clinic and manufacturing plant are in Thailand. Company: LifePoint, Inc. Ticker Symbol: AMEX: LFP Investor Relations Contact: Linda H. Masterson Phone: (909) 418-3000 x400 E-mail: LifePoint@LFPT.com Company URL: www.LifePointInc.com Company description: LifePoint, Inc., a leader in non-invasive drug diagnostic technologies and solutions, has developed, manufactures and markets the IMPACT Test System - a rapid diagnostic testing, screening and drug monitoring device for use in law enforcement and the workplace, and in the future, ambulances, pharmacies, and home healthcare markets. LifePoint's patented and proprietary technologies for the use of saliva as a non-invasive, blood-comparable test specimen, used in conjunction with the flow immunosensor technology licensed from the United States Navy, have allowed LifePoint to develop a broadly applicable, rapid, on-site diagnostic test system. The first product simultaneously detects drugs of abuse and alcohol. The initial three target markets - law enforcement, industrial workplace and medical emergency room - are estimated to be over $1.6 billion in total opportunity. Company: MacroChem Corporation Ticker Symbol: MCHM Media Contact: Jim Chiafery, (781) 596-0200 ext. 102 Investor Relations Contact: Kim Tulimieri, 781-862-4003 ext. 357 Phone: (781) 862-4003 E-mail: ktulimieri@macrochem.com Company URL: www.macrochem.com Product description: MacroChem is developing three drugs using its drug-absorption enhancer, SEPA(R): Topiglan(R), a Phase 2 topical treatment for erectile dysfunction; EcoNail(TM) a nail fungus treatment containing econazole, and Opterone(TM) a testosterone-deficiency cream. An Opterone dose-proportionality trial started in late 2003. An EcoNail Phase 1-2 tolerance-efficacy trial will commence in early 2004. Company description: MacroChem is a specialty pharmaceutical company that uses novel delivery systems to develop a range of pharmaceutical products to treat important medical conditions. Its current development portfolio contains products to treat testosterone deficiency, fungal infections of the toenails, and erectile dysfunction. MacroChem's core technology is modulation of skin absorption. Company: MethylGene Inc. Media Contact: rinowt@methylgene.com Investor Relations Contact: rinowt@methylgene.com Phone: 514-337-3333 E-mail: lienl@methylgene.com Company URL: www.methylgene.com Product description: MethylGene has a pipeline of novel targets and inhibitors which includes MG98 for oncology in clinical trials; MGCD010, a small molecule HDAC inhibitor for oncology with clinical trials to be initiated this year; small molecule inhibitors of bacterial beta-lactamases for antibiotic resistance in preclinical development in collaboration with Merck ; and a portfolio of other chemistry-driven research programs including HDAC inhibitors for other non-oncology large market indications. Company description: MethylGene is a private biopharmaceutical company engaged in the discovery and development of novel enzyme inhibitors for the treatment of cancer and infectious diseases. The Company has developed expertise in rational design of isotypic selective enzyme inhibitors and is a leader in the fields of histone deacetylase, DNA methyltransferase , and beta-lactamase. Strong partnerships with major pharmaceutical companies such as MGI Pharma, Taiho and Merck help drive our programs. Company: Munich Biotech AG Media Contact: markus.boecker@munichbiotech.com Phone: +49 89 899965-13, Fax. +49 89 899965-50 Company URL: www.munichbiotech.com Product description: Munich Biotech's most advanced compound is MBT-0206, an anti-neovascular cytotoxic agent, which is in phase II clinical trials in various solid tumor indications. In phase I, MBT-0206 was well tolerated and clearly showed anti-tumor activity. Munich Biotech's second anti-cancer drug MBT-0312 has started phase I clinical testing in Dec. 2003. Company description: Munich Biotech AG is a privately held pharmaceutical company. Its is developing "anti-neovascular cytotoxics", a new class of cancer drugs with a novel cellular target, the activated tumor endothelial cell. By destroying the blood vessels of solid tumors these agents are potentially effective in "chocking" of both the primary tumor and metastases. Company: MWG Biotech AG Ticker Symbol: NWU Investor Relations Contact: Dagmar Metzger Phone: 0049-8092-8289-985 E-mail: ir@mwgdna.com Company URL: www.THE-MWG.com Product description: In "Genomic Information" genomes of organisms are sequenced to identify which genes they contain. In "Genomic Synthesis" MWG produces synthetic nucleic acids, small fragments of DNA. The "Genomic Diagnosis" unit produces microarrays, glass slides with up to 30,000 spots, each of which represents a gene. Microarrays are used to identify gene function. MWG's "Genomic Technology" lab automation unit develops and produces THEONYX robot systems for molecular biology Company description: MWG-BIOTECH AG Application Solutions for the Life Sciences MWG Biotech is a provider of complete solutions around DNA. With its four business units Genomic Information (sequencing), Genomic Synthesis (production of synthetic nucleic acids), Genomic Diagnosis (microarrays) and Genomic Technology (robots lab automation) and with a strong bioinformatic backbone MWG Biotech offers its customers complete application solutions on the exciting path from genome to gene function. Company: NeuroMed Technologies Inc. Media Contact: Julie Jang Phone: 604.822.9970 E-mail: info@neuromedtech.com Company URL: www.neuromedtech.com Product description: NeuroMed Technologies is the only biotechnology company focused exclusively on calcium channels as drug targets for the treatment of neurological diseases. NeuroMed will commence its first clinical trial in early 2004 for its lead chronic pain candidate, NMED-160. Company description: NeuroMed Technologies Inc. is a private biopharmaceutical company committed to developing the next generation of chronic pain drugs with pipeline programs in anxiety, epilepsy and cardiovascular diseases. The Company's drug development programs are designed around validated clinical targets associated with large unmet markets. Company: Norgen Biotek Corp. Investor Relations Contact: Yousef Haj-Ahmad Phone: 905-227-8848 E-mail: yhaj-ahmad@norgenbiotek.com Company URL: www.norgenbiotek.com Product description: Based on its technology Norgen began to manufacture bio-consumable products dealing with the genomics and the proteomics research markets. In addition to its branded products, Norgen offer private labeling to a number of companies. Norgen's current focus is on the adoption of its novel technologies to the industrial scale purification of nucleic acids and proteins and on manufacturing/marketing its growing list of products. Company description: Norgen is a privately owned Canadian Biotechnology Company. It operates out of a stand-alone building equipped with all the necessary tools. Norgen is seeking a joint venture/financing to build a versatile cGMP facility to demonstrate the applicability of its patented platform technologies in the purification of nucleic acids, pharmaceutical and non-pharmaceutical proteins as well as to market it growing list of products. Company: Opexa Pharmaceuticals, Inc. Public Relations Contact: Michael T. Redman Phone: 281-775-0600 E-mail: Redman@opexapharma.com Web Address: www.opexapharma.com Company description: Opexa Pharmaceuticals, Inc., founded in 2001, is engaged in the development of therapeutics for autoimmune diseases and graft rejection. The company's lead product, Tovaxin, is currently being evaluated in a Phase I/II dose-escalation trial under an IND approved by the FDA. To date, more than 130 patients have been treated with Tovaxin. Opexa anticipates that Tovaxin will be a chronic treatment dosed subcutaneously twice per year. The underlying technology of Tovaxin is T cell vaccination. Tovaxin has been shown to deplete myelin-reactive T cells, the underlying cause of MS. Company: Predix Pharmaceuticals Holdings, Inc. Investor Relations Contact: Christine Hayden Phone: 781-376-0821 X1010 E-mail: hayden@predixpharm.com Company URL: www.predixpharm.com Product description: Predix Pharmaceuticals has created a proprietary suite of in silico technologies for the rapid discovery and optimization of G-protein coupled receptor (GPCR) targeted drugs. PRX-00023, a 5HT1A full agonist for treatment of ADHD, anxiety and depression, has entered phase I clinical trials. Preclinical stage 5-HT4 partial agonist and 5-HT2B antagonists are expected to enter clinical trials within 1 year. Company description: Predix Pharmaceuticals is an integrated computational - medicinal chemistry drug development company focused on creating new drugs targeted to GPCRs. Using our proprietary GPCR models and integrated computational-medical chemistry lead optimization algorithms, the 32-employee company has the capacity to discover, develop, and move 1-2 drug candidates into the clinic annually. Company: Serenex, Inc. Investor Relations Contact: Ian A.W. Howes Phone: (919) 281 6031 E-mail: ihowes@serenex.com Company URL: www.serenex.com Product description: Serenex has lead compounds in oncology and RA developed from its chemo-proteomics technology. Serenex profiles compounds across more targets in a single step than the entire pharmaceutical industry has screened in its history and gains a level of compound selectivity knowledge that exceeds current industry standards by up to 100-fold. Company description: Serenex is a drug discovery company based near Research Triangle Park in North Carolina. The company was founded in 2001 and has built a robust drug discovery engine, an internal product pipeline and nine pharmaceutical collaborations around its proprietary compound-centric chemoproteomics technology platform. Company: Stressgen Biotechnologies Corp. Ticker Symbol: SSB Media Contact: Donna Slade, 858.202.4945 Investor Relations Contact:Jennifer Matterson Phone: 250.744.2811 E-mail: jmatterson@stressgen.com Company URL: www.stressgen.com Product description: HspE7 is based on the covalent bonding of a heat shock protein (Hsp), to proteins such as viral or cancer antigens. The resulting CoValTM fusion proteins are designed to stimulate immune responses in the disease-specific antigen present in the fusion. CoValTM fusions use the body's immune system to combat infectious diseases or cancer. Company description: Stressgen Biotechnologies is focused on the discovery, development, and commercialization of innovative, proprietary immunotherapeutics for the treatment of infectious disease and cancer. The Company's proprietary platform technology is based on the covalent bonding of a stress protein, also called a heat shock protein (Hsp), to proteins such as viral or cancer antigens. Company: Symbollon Pharmaceuticals, Inc. Ticker Symbol: OTCBB: SYMBA Media Contact: Paul C. Desjourdy, 508-620-7676 x202, paul_desjourdy@symbollon.com Investor Relations Contact: Barry Kaplan, 732-747-0702, smallkap@aol.com Company URL: http://www.symbollon.com Product description: Symbollon has completed Phase II clinical trials evaluating IoGen(TM) as a potential treatment for cyclic breast pain associated with fibrocystic breast disease. IoGen achieved a 50% reduction in patient' breast pain in Phase II. Phase III trials are planned for May 2004. Additional indications include endometriosis, ovarian cysts and pre-menopausal breast cancer prevention. Company description: Symbollon is a specialty pharmaceutical company focused on developing proprietary drugs based on its molecular iodine formulation technology. Molelcular iodine is the active species of iodine, a proven fast acting, broad-spectrum antimicrobial and therapeutic. Symbollon is developing product applications for its technology in two distinct areas: women's healthcare and infection control. Company: Therion Biologics Corporation Media Contact: Beth Preston, 617-761-6739 Investor Relations Contact: George Eldridge, 617-475-7212 E-mail:info@therionbio.com Company URL: www.therionbio.com Press Kit URL: http://www.therionbio.com/news.html Product description: Therion Biologics designs off the shelf cancer immunotherapies (cancer vaccines). This therapy is designed to stimulate a patient's immune system to identify, attack, and eliminate cancer cells. Earlier trials indicate that the therapy may delay or stop disease progression and may increase overall survival. Company description: Therion Biologics Corporation develops therapeutic vaccines for cancer and preventive vaccines for AIDS. The Company has two lead programs involving multiple clinical trials: PANVAC-VF(TM) for pancreatic cancer and PROSTVAC-VF(R) for prostate cancer. Therion is also applying its technology platform to develop vaccines to treat melanoma, breast cancer and other solid tumors. Therion Biologics is headquartered in Cambridge, Massachusetts. Company: Transave, Inc. Media Contact: Gerald Baty Phone: (732) 438-9434 ext. 31 E-mail: jbaty@transaveinc.com Company URL: www.transaveinc.com Product description: Transave's first two products are: 1) a chemotherapeutic for lung cancer; and 2) an anti-infective for pseudomonas infections in Cystic Fibrosis patients. These products contain off-patent drugs that are limited in their use due to their toxicity and dosing requirements. These are problems which Transave, with its SLIT(TM) technology, can resolve. Company description: Transave is focused on the development of multiple product lines of therapeutics for lung diseases via the use of its proprietary technology. This technology, Sustained release Lipid Inhalation Targeting (SLIT(TM)), has wide applicability in the development of either existing or new therapeutics for the site specific treatment of lung diseases. Company: Viral Therapeutics, Inc. Investor Relations Contact: Lee Henderson Phone: 607-266-0860 E-mail: lah@viral-therapeutics.com Company URL: www.viral-therapeutics.com Product description: Virusorb is safe and effective against all strains of Influenza virus both in vitro and in animals. The target market is designed for fast track status. Vagiprev is a microbicide/spermicide/antifungal targeted to several markets with a focus on unmet needs. Clinical trials are to begin in 2004. Company description: VTI has developed numerous products for large pharma and biotech companies that are in various stages of clinical testing and in diagnostic markets. The company has proprietary technologies to gain advantage in the market for both products and unique development tools focused in gene/protein expression and genomics tools and resources. Company: Zelos Therapeutics, Inc. Investor Relations Contact: Robert DuFresne Phone: 781.547.5857 E-mail: ddufresne@zelostherapeutics.com Company URL: www.zelostherapeutics.com Company description: Zelos Therapeutics Inc. is a product development focused biotechnology company established in June 2000 to develop technology from the National Research Council Canada (NRC) for the treatment of osteoporosis, psoriasis and other diseases. Zelos has an exclusive, worldwide license covering all fields of use for NRC technology consisting of a unique family of small osteogenic (bone stimulating) analogues of PTH. Product description: Zelos' first compound is now in Phase I clinical development and a second program is expected to enter clinical development within the 2004 calendar year. The Phase I stage compound, Ostabolin-CTM for injection, an analogue of the naturally occurring Parathyroid Hormone (PTH), is under development for the treatment of osteoporosis. PTH and PTH analogues represent the first (and currently the only) true "bone-building" treatment for osteoporosis. These compounds have generated extensive clinical data over the past 30 years demonstrating the therapeutic ability in osteoporotic patients to significantly increase bone mineral density (BMD) and decrease fracture risk. Zelos expects that Ostabolin-CTM will be the third PTH product to reach the market. |
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