SUR10 Isolated splenic metastasis from primary lung adenocarcinoma. (Surgery).

SUR10 ISOLATED SPLENIC METASTASIS FROM PRIMARY LUNG ADENOCARCINOMA. Brian J. Schmidt, MD, and Stephen L. Smith, MD. Department of General Surgery, Mayo Clinic Jacksonville, Jacksonville, Fla.

Metastatic disease involving the spleen is uncommon, and isolated metastasis to the spleen is even more rare. Most patients with splenic metastases have widely disseminated metastatic disease. A current literature review shows the incidence of isolated splenic metastasis ranges from 0% to 26% of all patients with splenic metastases. The reported primary malignancies of patients with splenic metastases include melanoma, lung, colorectal, endometrial, ovarian, thyroid, pancreatic, and gastric cancers. Although most patients with splenic metastases are clinically asymptomatic, there have been reports of painful splenomegaly, splenic vein thrombosis, and splenic rupture. This demonstrates that diagnosis and prompt therapeutic intervention are important. The time from diagnosis of a primary tumor to the discovery of splenic metastases ranges from fifteen to forty-two months in the literature. We report a case of an asymptomatic isolated splenic metastasis in a 72-year-old man diagnosed 25

months after resection of an adenocarcinoma of the lung.