Printer Friendly

STUDY LINKS INTERLEUKIN TO PERIODONTAL DISEASE

 NEWARK, N.J., Nov. 19 ~PRNewswire~ -- Detection of periodontal disease has been advanced through a recently completed research study that focused on an immune system reaction.
 It has been estimated that more than half of all American adults have some evidence of periodontal disease which can cause damage to supporting dental tissues and tooth loss.
 Utilizing Cistron's Interleukin-1 beta (IL-1) assay in a study of 132 subjects at the UMDNJ - New Jersey Dental School, Newark, it was found that IL-1 levels were significantly higher in the gingival fluid of subjects with periodontal disease than in that of healthy subjects or those with gingivitis. IL-I is a key protein in the human immune system but an overproduction of IL-1 can cause inflammation and bone resorption.
 The study was funded by an SBIR Phase I research grant from the National Institutes of Health (NIH). If approved, a Phase II grant from the NIH would enable Cistron to further its studies on a larger number of subjects over a two-year period. The aim of the Phase II study would be to develop an in-office test to aid dentists in detecting periodontal disease and in monitoring the effectiveness of treatment.
 UMDNJ is New Jersey's university of the health sciences.
 Cistron's primary product area is immune system regulators, known as lymphokines which include IL-1 beta. The company manufactures and sells lymphokine assay kits to pharmaceutical companies, the government and academic institutions in the United States, Europe and the Far East for cancer, arthritis and other autoimmune disease research.
 -0- 11~19~92
 ~CONTACT: Harold Smith of Hal Smith Associates, 201-305-0244, for Cistron~


CO: Cistron ST: New Jersey IN: MTC SU:

AH-OS -- NY003 -- 2700 11~19~92 09:01 EST
COPYRIGHT 1992 PR Newswire Association LLC
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1992 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:PR Newswire
Date:Nov 19, 1992
Words:284
Previous Article:SECOND CHARLESTOWN RESIDENT SENTENCED FOR BANK ROBBERY
Next Article:GAMMA LAUNCHES ITS FIRST CRUISE SHIP GAMING VENTURE
Topics:


Related Articles
Periodontitis Is Strongly Linked To Preterm Birth.
Maternal Periodontal Disease Tied to Preterm Birth.
INTERLEUKIN MAPS NOVEL SNP FOR KEY INFLAMMATION GENE.
Periodontal disease raises preterm risk.
Interleukin Genetics Completes Enrollment of Studies in Japan and China on Genetic Risk for Osteoporosis and Cardiovascular Disease.
Interleukin Genetics Initiates Study of Genetics of Osteoarthritis with New York University Medical Center.
Interleukin Genetics to Present at the 13th International Conference on Periodontal Research.
Interleukin Genetics Licenses its PST(R) Genetic Test to OralDNA Labs.
Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections.
Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections.

Terms of use | Copyright © 2016 Farlex, Inc. | Feedback | For webmasters