SCIENCE NEWS of the Year.

Years ago, fresh out of a statistics course, I made some friends laugh by insisting that an election shouldn't be considered valid unless the difference between the vote counts is statistically significant. I was viewing an election as an experiment with the hypothesis that more of the voters wanted candidate A than candidate B. I didn't pursue the idea because a vote count seemed to me to be a fixed result. How could you measure variability without holding the election repeatedly day after day? Was I naive! I knew nothing then of chad or dimpled ballots, and I hadn't considered what it would really be like to count millions of ballots.

Nevertheless, when statisticians attracted the spotlight in the presidential election this year, I felt vindicated. While some calculated that many people had made mistakes in marking a butterfly ballot and others estimated how various recounts might change the tallies, a few made just my point. For example, mathematician John Allen Paulos of Temple University in Philadelphia figured that the difference between the Florida vote totals of Al Gore and George W. Bush is no more than that expected between the number of heads and tails of a coin tossed 6 million times. So, he'd say the Florida vote could best, statistically speaking, be considered a tie.

Thankfully, nothing as significant as the nation's leadership rests on the outcome of a single scientific experiment. Researchers have the option of concluding that they didn't get a clear-cut answer to the question posed, and scientists often apply statistical tests to guide that judgment.

Because readers of SCIENCE NEWS want information that they can count on, we try to report only results that meet accepted confidence standards. This can be difficult because some scientists, in their enthusiasm, gloss over uncertainties. Only occasionally do we deliberately report a result that falls short of statistical significance, and then we point out its tentative nature. For example, in a recent report on the long-term health of calorie-restricted monkeys (SN: 11/25/00, p. 341), we included a preliminary finding. We considered the topic to be of great interest, the results of such studies slow in coming, and our readers unlikely, without more solid evidence, to do anything more drastic than cutting back on desserts. Perhaps such results can best be regarded in the same light as a voter poll held months before the election.

Anthropology & Archeology

* A pair of 1.7-million-year-old fossil skulls discovered in Asia offered a glimpse of perhaps the first species of human ancestors to exit Africa (157: 308).

* Evidence in a sand dune suggested that people inhabited southeastern Virginia at least 15,000 years ago (157: 244*).

* Chinese finds indicated that Stone Age folk made hand axes across a surprisingly broad swath of Asia (157: 148*).

* Controversial new clues to possible cannibalism emerged in the prehistoric U.S. Southwest (158: 164*).

* An analysis of the Y chromosome in modern men enlivened debate over human evolution (158: 295), as did reports on DNA specimens retrieved from Neandertal fossils (157: 213*; 158: 21).

* Researchers contended that many Stone Age statuettes of women found across Europe depict previously unrecognized items of clothing (158: 261).

* Mounting evidence portrayed whales and dolphins as cultural creatures that transmit knowledge socially (158: 284*).

* New insights into the genetics of body development raised doubts about the statistical method that many anthropologists use to create evolutionary trees (158: 346).

* A cross-cultural investigation concluded that the child-rearing practices in some modern forager groups perpetuate trust and sharing (158: 8).

* Excavation of a 125,000-year-old site on the African coast of the Red Sea markedly pushed back the date of the earliest seaside settlement (157: 292).

* Scientists observed greetings among wild baboons and other clues to the mental lives of these primates (157: 280).

Astronomy

* In some of the coldest regions on Mars, water appears to have recently gushed from just beneath the surface (158: 5*). Images suggest that parts of Mars were once lands of lakes and reveal places to look for evidence of life (158: 372*).

* NASA's two most recent missions to Mars failed because they were underfunded, managed by inexperienced people, and insufficiently tested, a panel found (157: 215). Revamping its Mars program, NASA announced it would delay by nearly a decade plans to bring back material from the Red Planet (158: 310).

* A galaxy map revealed the largest structures in the cosmos (158: 104).

* Two new X-ray observatories opened a window on the most energetic cosmic events (158: 266*), while astronomers progressed in designing an X-ray mission that would image coronas of nearby stars and black holes (158: 292).

* Supermassive black holes at galaxy cores proved far more numerous than visible-light surveys had indicated (157: 53*).

* New evidence supported the notion that Jupiter's moon Europa contains an ocean beneath its icy surface, and a scientist proposed a novel way for Europa to have obtained the energy required to sustain life within that ocean (157:70). A combination of images, spectra, and magnetic field measurements suggested that another Jovian moon, Ganymede, may also have had and may still harbor an ocean (158:404*).

* Preliminary tests supported the notion that the expansion of the universe is accelerating (157: 106*).

* On Valentine's Day, the NEAR spacecraft cozied up to the asteroid 433 Eros, becoming the first craft to orbit a tiny body (157:118). NEAR found evidence that the rock dates from the birth of the solar system (157: 375) and took the sharpest images yet of an asteroid (158: 293).

* Evidence grew that life's evolutionary explosion on Earth some 540 million years ago occurred around the time that cosmic debris began pummeling our planet at an increasing rate (157: 165*). New research also suggested that a swarm of debris bombarded the moon, and likely Earth, some 3.9 billion years ago, about the time life may have debuted on our planet (158: 357*).

* Scientists isolated carbon spheres--and perhaps trapped extraterrestrial gas--from meteorites (157: 196*).

* A meteorite that fell in the Yukon may date from the solar system's birth (157: 235).

* Astronomers found evidence of extrasolar planets similar in size to those of the solar system (157: 220) and the nearest known extrasolar planet (158: 84*). For the first time, they obtained images of as many as 18 objects that, based on their mass alone, could qualify as extrasolar planets (158: 228*). A controversial study claimed that nearly half the objects reported to be extrasolar planets are merely lightweight stars or star wannabes known as brown dwarfs (158: 277*).

* Spacecraft data suggested that otherwise invisible comets could be detected by searches for their tails (157: 228*).

* A balloon-borne experiment found that the cosmos is perfectly flat (157: 276*).

* Half of the universe's hydrogen gas, which hasn't been accounted for, may reside in relatively nearby reaches of intergalactic space (157: 310*).

* Astronomers discovered the most distant galaxy so far detected (157: 340).

* Researchers developed detailed maps of the distribution of dark matter, the invisible material believed to make up 90 percent of the universe's mass (157: 332).

* Galaxies are surrounded by vast halos of dark matter that may extend at least 1.5 million light-years from their centers (157: 36*).

* Physicists duked it out over the existence of WIMPs, elementary particles that could solve a mystery about the universe's dark matter and help unify the four fundamental forces of nature (157: 131).

* Scientists made progress in understanding the origin of solar storms, predicting when and how they will erupt and estimating when they might strike Earth (157: 183, 245, 404*; 158: 214).

* A simple sugar was spotted in interstellar space for the first time (157: 405).

* Earth's home galaxy indulged in cannibalism to assemble its so-called visible halo, three studies found (157: 261).

* Telescope images of what may be a close-up view of galaxy formation suggested that some streams of gas and dust that are ripped out of large galaxies can form into galaxies of their own (157: 151).

* Astronomers may finally have evidence that a spinning object drags space-time along with it (158: 150).

* A communications problem was revealed that could prevent the Huygens probe from relaying all its data when it parachutes through the atmosphere of Saturn's largest moon, Titan, in 2004 (158: 262, 298).

Behavior

* Eye-opening evidence suggested that sleep contributes to certain types of memory formation (158: 55, 358). Other studies examined sleep deprivation's disturbing effects on the brain (157: 103*) and its widespread occurrence among children by the time they reach the sixth grade (157: 324*).

* Psychologists conducted a series of studies indicating that East Asian and Western societies foster contrasting mental approaches to reasoning (157: 56).

* A survey of public elementary schools in parts of North Carolina found that more than half of those children receiving stimulant medication don't exhibit the attention-deficit hyperactivity disorder for which physicians prescribe the drugs (158: 69*).

* An analysis of babies' babbling yielded insights into the biomechanics of talking and possibly the nature of prehistoric languages (157: 344*).

* In a laboratory experiment, monkeys exhibited signs of perceiving simple melodies much as humans do (158: 180).

* A controversial national survey warned of growing social isolation among frequent Internet users (157: 135*).

* Review of a Food and Drug Administration database suggested that placebo pills given to depressed people work well enough to dispel ethical concerns about using placebos in studies of antidepressants (157: 278*).

* Scientists explored the social roots and psychological aftermath of violent conflicts in many parts of the world (158: 88*).

* New evidence strengthened the theory that some families carry a genetic susceptibility to obsessive-compulsive disorder and tic disorders that gets triggered by childhood strep infection (158: 151).

* Researchers explored family and psychological forces that influence the mood swings of bipolar disorder (157: 232*).

* Fundamental aspects of hearing and vision separately influence children's ability to read, so investigators suggested that certain types of perceptual training may be useful in reading instruction (157: 180*).

* A large sample of young adults tracked since childhood in New Zealand yielded evidence of a link between violent behavior and three mental illnesses: alcohol and marijuana dependence and a condition characterized by a range of psychotic experiences (158: 279).

Biology

* Two rival groups, one public and one private, announced that each has read most of the 3 billion or so DNA subunits that spell out the human genome (158: 4*).

* Drugs that defuse so-called free radicals lengthen a worm's life span by more than 50 percent (158: 238), and a gene mutation doubles it (158: 391).

* Research on stem cells--immature cells that can grow indefinitely and mature into various cell types--exploded. Stem cells may treat damaged corneas (158: 36), brain disorders (158: 63), and spinal injuries (157: 6). Stem cells in bone marrow can form liver cells (158: 7) or brain cells (158: 55). Human skin and scalp tissue may also provide a source of brain stem cells (158: 360), and the brain's stem cells can replace damaged nerve cells with new ones (158: 63).

* A biotech company announced the first cloning of pigs (157: 197), and biologists suggested that cloned animals live longer than normal (157: 279).

* To help preserve biodiversity, negotiators from 130 nations crafted rules of conduct for international trade in living, genetically engineered organisms (157: 84).

* Scientists identified a protein in taste buds that recognizes monosodium glutamate (157: 68) and proteins that work as taste receptors for bitterness (157: 196*).

* In work that may lead to vaccines, biologists sequenced the genes of two strains of a bacterium that causes meningitis (157: 116*). They also deiphered complete genomes of bacteria responsible for cholera (158: 120) and tuberculosis (158: 270).

* Biologists read the full DNA sequence of the fruit fly (157: 132, 382) and discovered a sleeplike state in the insect (157: 117*).

* A protein originally found in frogs appears to be the long-sought light detector for the human biological clock (157: 120).

* A cold virus that produces obesity in mice and chickens seems to play a role in human corpulence (158: 87).

* Seeking to explain how antibiotics work, scientists found a protein that commands bacteria to kill themselves (157: 101).

* Researchers found that mice detect pheromones using nerve cells distinct from those of the main olfactory system (157: 390).

Biomedicine 

* Transplants of cells that make insulin boosted the potential for a cure for diabetes (157: 165; 158: 156). A rapidly developing form of diabetes in children appeared to be the result of unrecognized chemicals or viruses destroying insulin-making cells (157: 86*).

* Researchers discovered that people with a common version of the CAPN10 gene face an increased risk of getting adult-onset diabetes (158: 212).

* Veterans who suffered a moderate or severe concussion during World War II showed a heightened risk of Alzheimer's disease in old age (158: 276). A vaccine intended to slow or prevent Alzheimer's appeared promising (158: 38*). Ibuprofen seemed to lessen accumulation of beta-amyloid protein fragments in the brain, perhaps explaining how that common painkiller decreases Alzheimer's risk (158: 101*).

* As a strategy for slowing the development of bacterial resistance to antibiotics, researchers engineered drugs that self-destruct when exposed to sunlight (157: 5). Other groups worked to defeat antibiotic resistance by disabling the drug-expelling pumps in the microbes' cell membranes (157: 110). When Denmark decreased its use of antibiotics in livestock, the prevalence of drug-resistant bacteria in meat fell (158: 95).

* New research suggested that periodic treatment breaks for AIDS patients may boost their immune response against HIV (157: 248). An experimental AIDS vaccine bolstered with two immune proteins protected rhesus monkeys from the disease (158: 260*).

* Although gene therapy caused the death of a patient late in 1999, in 2000, the new technology recorded several successes. They include reversing an immune disease in babies (157: 277), spurring bone repair in mice and rats (157: 357), and curing hemophilia in mice (157: 309). New methods of delivering genes promised to help gene therapy reach its potential (157: 309). As a step toward reawakening neurons in people with spinal cord damage, a version of the polio virus delivered genes to motor neurons without harming them (158: 166). Finally, lessons from gene therapy promoted viruses as cancer fighters (158: 126*).

* Providing the first evidence in primates for effective inoculation against deadly Ebola virus, a vaccine combo tested well in monkeys (158: 358). Also, Ebola proved to have a surface protein that kills cells lining blood vessels (158: 85*).

* Scientists induced an immune response against pancreatic cancer by injecting blood cells from healthy people into patients' tumors (157: 214).

* Research showed that anticholesterol drugs called statins stimulate bone growth and that a protein known as osteoprotegerin prevents bone from breaking down (157: 41*). The protein also reduces bone cancer pain in mice (157: 292*).

* A simple breath test may help physicians learn how people metabolize drugs and identify patients most likely to suffer side effects from chemotherapy (157: 332).

* Tiny tubes of steel mesh coated with a DNA-containing polymer could prevent arteries from becoming reclogged after cardiovascular treatment (158: 325).

* In chimpanzees, a new vaccine spurred an immune response against the malarial form that passes through the liver, and the response usually halted the parasite before it could cause disease (158: 310).

* A study of twins showed that heredity plays a role in ear infections (157: 136).

* Bacteria genetically engineered to secrete microbe-killing and anti-inflammatory compounds fought diseases in rats and mice (158: 244*).

* Suggesting a potential therapy for people with strokes or Alzheimer's disease, studies indicated that lithium, which is widely used to treat manic depression, stimulates production of new brain cells (158: 309).

* Researchers explored the mechanisms underlying links between low birth weight and chronic disease (158: 382*).

* A new study suggested that flawed insulin activity may lead to blood changes that foster atherosclerosis, even in people who aren't diabetic (158: 213).

* Scientists used patterns of gene expression to distinguish between two types of blood cancer that respond differently to treatment. (157: 239).

* Diets with severely reduced calories showed signs of lengthening lives and reducing disease in monkeys (158: 341*).

* Hypermethylation--a chemical alteration of DNA that can silence genes inappropriately--plays a role in nonhereditary breast cancer (157: 247, 407). Signs of this alteration could help physicians screen patients for lung cancer (158: 340).

* New studies found that the puzzling sleep disorder narcolepsy stems from destruction of a small group of brain cells (158: 148).

* A 6-year study showed that vitamins and antibiotics can reverse conditions that lead to stomach cancer (158: 391).

Botany & Zoology

* The latest inventory of life in the United States turned up an extra 100,000 species of plants, animals, and fungi, but it warned of threats to at least a third of those species (157: 219).

* Natural selection can act on large groups, according to a test on ecosystems that have thousands of species and were miniaturized to fit in flowerpots (158: 39).

* A novel comparison of 25 pairs of insect lineages found that sexual conflict plays a major role in making new species (158: 181).

* In a newly proposed scenario, hermaphroditic plants may evolve distinct gender forms in response to polyploidy (158: 214).

* The microscopic bdelloid rotifer has seemingly evolved without sex for some 40 million years and probably doesn't exist in male form--making this rotifer a good candidate for a robust asexual species, a much debated possibility (157: 326*).

* After 5 years of mystery, California pathologists announced that a fungus probably causes the tree disease called sudden oak death (158: 86).

* Marine iguanas in the Galapagos Islands are the first vertebrates known to reduce their size during a food shortage and then regrow to their original body length (157: 20*).

* Full-grown elephants imported into a park of destructive youngsters demonstrated that when older males enter the aggressive, testosterone-driven state called musth, they suppress that condition in younger males (158: 341).

* The eardrums of a tiny parasitic fly have a novel mechanism that enables the insect to pinpoint a sound's origin as well as owls and people do (158: 308).

* Researchers found a second bird genus in New Guinea that, like the pitohoui, carries toxins first identified in poison-dart frogs in Central and South America (158: 263).

* A study suggested that sacs bulging from a horse's auditory tubes keep the animal's brain from overheating during exercise (157: 69).

* New approaches to estimating age of bow-head whales in the Artic suggested that some live much longer than expected, more than 200 year instead of just 60 (158: 254).

* Pacific tree frogs downwind of California's agricultureal hotspots show reduced cholinesterase activity, a common symptom of pesticide exposure (158: 391).

Chemistry

* Scientists developed a new titanium-producing process that may eventually reduce the metal's cost to one-third its current price (158: 197*).

* Researchers coerced argon to join other elements to form a stable, neutral compound (158: 132).

* The first atomic-resolution map of a ribosome, the cell's protein factory, suggests that RNA catalyzes the formation of proteins (158: 100*).

* When physicists pulled out the inside cylinders of multiwall carbon nanotubes, the innards snapped back into place, suggesting that nanotubes could serve as frictionless bearings and springs (158: 71).

* A conch's tough shell resists fractures because protein surrounds the mineral crystals throughout the structure (158: 6).

* Chemists devised a method for identifying cocaine's geographical origin (158: 324*).

* Carrying out a widely used chemical reaction on one molecule at a time, researchers demonstrated unprecedented control of molecular behavior (158: 215*).

* Scientists coaxed green algae to produce hydrogen, a clean-burning fuel that could someday power pollutionfree cars (157: 134).

* Researchers synthesized what they suspect is the most powerful nonnuclear explosive known (157: 54*).

* Nuclear-waste storage may be modified in accord with a new understanding of the basic chemistry of plutonium (157: 39).

* Researchers replaced diamonds in a device for high-pressure studies with a new synthetic crystal that should allow work on larger samples of material than can be tested in the diamond devices (158: 278).

* A novel electrochemical method improved the surface of stainless steel without making the metal brittle or prone to corrosion (158: 263*).

* For the first time, researchers directly observed a protein begin to crystallize, and they found it has a peculiar shape (158: 84*).

* Scientists identified the chemical responsible for the yellow hue of many flowers, moving a step closer to engineering sunny-colored designer buds (158: 311).

Earth Science

* Scientists determined that temperatures of the northern Pacific within the past 2 years veered from one extreme to the other, potentially altering North American weather for a decade or so (157: 69*).

* People's activities, not volcanoes, proved to be the main source of ozone-depleting chlorofluorocarbons in the atmosphere (157: 118).

* Airborne measurements showed that layers of smoggy, ozone-rich air from Asia can reach the United States (157: 4).

* Satellite observations of clouds indicated that some types of airborne pollution can break up water droplets and suppress rainfall (157: 164*).

* For the first time, scientists detected atmospheric [[SF.sub.5][CF.sub.3]], a greenhouse gas that traps heat more effectively than any other previously found in air (158: 70).

* NASA studies showed that the vast center of Greenland's ice sheet isn't getting thinner, but most of its margins are, contributing to rising sea levels (158: 54).

* Up to a quarter of the humanmade structures within 500 feet of America's coastlines may be lost to erosion by 2060, according to a federal report (158: 21).

* A Connecticut-size iceberg split from the Ross Ice Shelf in Antarctica (157: 215).

* Satellite images confirmed that the northern United States had much less snow cover than normal this spring, following North America's warmest winter on record (158: 87).

* In one of the Worst fire seasons in decades, wildfires seared the western United States throughout the summer (158: 101).

* A new computer model suggested how earthquakes can happen at fault zones located far from the edges of a tectonic plate (158: 212).

* A study of long-lasting fluctuations in the temperature and volume of water spewing from hydrothermal vents after an undersea earthquake suggested that the flow into vents is complex (158: 183).

* A survey of Mount Everest altered its official elevation to 29,035 feet (157: 11).

* Computer simulations found that a swath of unfrozen ocean may have hugged the Earth's equator even during the most frigid global-climate episodes (157: 343).

* Polar stratospheric clouds, which drive ozone loss in Antarctica, turned up in force during the most recent Arctic winter (157: 356*).

* Mystery solved: Long-term fluctuations in pressure at the ocean's bottom appear to drive the Chandler wobble, which causes the North Pole to wander a path of about 20 feet every 14 months (158: 111).

* By analyzing impurities, researchers measured remnants of the gargantuan pressure that formed diamonds (158: 260).

* Geologists said that significant portions of the Grand Canyon, usually considered the product of eons of erosion, may have been carved within the past million years or so (158: 218).

Environment & Ecology

* Negotiators reached agreement on the draft of a treaty to ban or phase out some of the world's most persistent and toxic pollutants (158: 389).

* Scientists in the United States offered the first confirmation of something their European counterparts have been reporting for years--widespread drug pollution of surface, ground, and tap water (157: 212*). Drug concentrations were at times high enough to alter the apparent gender of fish and, perhaps, their fertility (157: 388*).

* Air concentrations of ozone in many areas are high enough to induce leakiness in people's lungs, a study found (157: 308*).

* Ballast water can move huge quantities of cholera germs and other microbes between ports around the globe (158: 348).

* Satellite imagery showed that sprawling urban development is disproportionately gobbling up the land best able to support crops (157: 155). Other analyses linked the traffic associated with urban sprawl to an unexpectedly large rain of pollutants into local waters (158: 332).

* A government review concluded that young boys exposed to the phthalates in many plastics, cosmetics, and medical supplies could develop reproductive impairments (158: 152*). Subsequent studies showed that these hormone mimics are present in U.S. residents and that they could be fostering premature breast development in girls (158: 165*).

* A California study indicated that some cars' catalytic converters foster the production of ammonia, a pivotal ingredient in the urban haze and in the particulate pollution that the devices were designed to reduce (158: 133*).

* DDT and other estrogen-mimicking pollutants showed the capacity to transform male fish into mothers that produce viable young (157: 87). At the same time, public health officials around the world lobbied to preserve DDT for killing malaria-carrying mosquitoes (158: 12*).

* After reviewing new studies that demonstrated biological effects in animals and people exposed to cell-phone frequencies, a British review of research offered the devices a guarded endorsement (157: 100*, 326).

* Studies confirmed that corn engineered to make a bacterial toxin--the Bt pesticide--can kill caterpillars of nontarget species (158: 184). However, the Bt toxin in different corn strains varied widely in nontarget lethality (157: 372*).

* The unusually invasive seaweed that has been smothering coastal seafloor areas of the Mediterranean showed up in California waters, prompting an immediate campaign to break the invaders' toehold in the Americas (158: 36*, 83, 332).

* A few neighbors burning trash that includes plastic may generate more toxic dioxins than a well-run municipal incinerator, analyses showed (157: 70).

* Men who were exposed in the womb to dioxinlike pollutants from their mothers produce impaired sperm (158: 303*), researchers reported. Others found increased ratio of girls to boys among the offspring of men who had high dioxin exposures (157: 358*).

Food Science & Nutrition

* The National Institute of Medicine increased the recommended daily intake of dietary antioxidants, such as vitamins C and E (157: 244).

* Studies found that for bone health, there is little carryover benefit from calcium supplementation once it ends (157: 260*). Other research showed that calcium, especially from dairy products, can switch the body's fat cells from storing calories to burning them (157: 277*).

* U.S. cattle were shown to have high rates of toxic bacterial infections that lead to widespread carcass contamination at slaughter (157: 199*).

* A study found that consuming lots of oranges, other citrus fruits, or citrus juices can raise the concentrations of good cholesterol in a person's blood (158: 327).

* Though a new study found that drastic salt restriction can lower blood pressure, even in people without hypertension, some critics challenged the finding's value in setting guidelines for all adults (157: 340).

* Preliminary studies indicated that moderate consumption of chocolate may offer cardiovascular benefits (157: 188*).

* Low-fat diets may greatly increase heart-disease risk in people who have impaired insulin action, including many without diabetes, researchers found (157: 236).

* The federal government approved irradiation of raw meat, the only technology known to kill an especially lethal strain of bacteria (157: 40).

* A study of vitamin E found that megadoses may reduce the risk of heart disease in people with diabetes and other conditions that produce chronic, low-grade inflammation (158: 311).

* University scientists developed biodegradable plastics that release natural germ-killing agents to the foods wrapped in them (158: 221).

* Dutch neuropsychologists reported that drinking a milk-derived protein that yields a mood-enhancing amino acid may help vulnerable people cope with stress (158: 23).

Mathematics & Computers

* In an unexpected result concerning partitions, which are whole numbers written as sums of smaller numbers, mathematician Ken Ono proved there are infinitely many partition congruences (157: 396*).

* The data-scrambling technique called Rijndael won the worldwide competition to become the federal government's advanced encryption standard (158: 231).

* A new theorem opened a path to a proof of Catalan's conjecture, a venerable problem concerning consecutive powers of whole numbers (158: 356).

* Researchers in computational geometry demonstrated that any crinkly polygon can be unfurled into a convex shape without letting the sides cross each other (158: 200*).

* Mathematicians reached a milestone in algebraic number theory by proving the local Langlands correspondence, a conjecture that concerns prime numbers and perfect squares (157: 47).

* Proved: The standard double-bubble configuration, familiar to soap-bubble enthusiasts, represents the least surface area when the two bubble volumes are unequal (157: 77).

* The malicious ILOVEYOU computer virus, spread via an E-mail attachment, shut down hundreds of thousands of computers and caused several billion dollars in damage around the world (157: 351).

* A quantum computation using a custom-built molecule with five fluorine atoms furnished experimental evidence that a quantum computer can solve certain mathematical problems more efficiently than a conventional computer can (158: 132*).

* Studies provided insight into the vast extent, intricate structure, and robustness of the World Wide Web (157: 351; 158: 125).

* The Goldbach conjecture--that every even number is the sum of two primes--was shown to be true up to 4 x [10.sup.14] (158: 103*).

Paleobiology 

* A fossilized dinosaur heart similar to that of birds and mammals provided further evidence that dinosaurs may have been warm-blooded (157: 260*).

* A supposed missing link between dinosaurs and birds turned out to be fossil fakery that combined bones from two different animals (157: 38*).

* The massive extinctions at the end of the Permian period 250 million years ago could have occurred within a mere 8,000 years, scientists suggested (158: 39).

* An anatomically primative, 92-million-year-old ant, trapped in amber, pushed back the first record of its subfamily by 40 million years (158: 343).

* Paleobiologists said that tiny fossils from the ears of fish that survived worldwide extinctions about 34 million years ago suggest that cooler winters caused the die-off (158: 287).

* Researchers found that Caudipteryx, a feathered animal that lived 120 million years ago, may have been a flightless bird, not a bird ancestor (158: 119).

* Fossil tracks of an unknown bird from 110-million-year-old Korean sediments pushed back evidence of web-footed birds by at least 25 million years (158: 111).

* The bones of six carnivorous dinosaurs discovered in a fossil bed in Patagonia indicated that the big meat eaters were social creatures (157: 223).

Physics

* An experiment confirmed the existence of the tau neutrino (158: 68), last of the 12 fundamental subatomic building blocks of matter. Possible sightings of the Higgs boson--a longs-ought particle thought to confer mass on other particles--hint that it may also turn up soon (158: 196*, 294*, 381).

* A European particle accelerator may have produced the first traces of a primordial state of matter called the quark-gluon plasma (157: 117*). A new, more powerful, U.S. accelerator began experiments also intended to make that plasma (158: 136*).

* Sparking controversy, a theorist suggested that electrons in liquid helium can break into pieces dubbed electrinos (158: 216*).

* Experiments demonstrated that pulses of electromagnetic radiation can outpace light's nominal speed limit of 300 million meters per second, fueling more debate over whether information also can travel at superluminal speed (157: 375*).

* Physicists combed experimental data for newly predicted signs that extra spatial dimensions exist and alter gravity (157: 122*). A new measurement found only normal gravity down to as little as a 0.2 millimeter separation between masses (157: 311).

* A novel technique promised to make ultra-precise measurements of light frequencies widespread (157: 359*).

* Observations of mad dancing by tin atoms on a copper crystal overturned conventional ideas of how bronze and other alloys form on surfaces (158: 340*).

* Researchers built a device that, with electrical and magnetic properties contrary to those of ordinary materials, is expected to respond to microwave radiation in extraordinary ways (157: 198).

* Accelerator experiments confirmed predictions that electrons orbiting an atom's nucleus can directly excite the nucleus (158: 207).

* Atomic physicists demonstrated matter amplification that's analogous to amplification of light in a laser beam (157: 15).

* The quantum nature of mechanical vibration and heat flow became evident in an experiment probing heat dissipation in nanometer-scale structures (157: 279).

* Molecules were made in ultracold atom clouds called Bose-Einstein condensates (BEC)--a possible step toward molecular BECs (157: 104).

Technology

* Researchers wired the living brain of a sea lamprey to a small, wheeled robot in the first example of two-way communication between neurons and a machine (158: 309*).

* Interactions between strands of DNA served as fuel to power tiny machines, including one made of DNA (157: 246; 158: 159).

* Despite looming fundamental limits, electronics researchers raced to find new ways to continue shrinking microcircuit components (157: 204*; 158: 350*).

* Better feed, medicines, and water tanks improved the outlook for fish farms that recirculate water and thereby cut pollution (157: 314*).

* Manufacturers debuted industrial-grade cables, motors, and other power devices made with high-temperature superconductors--materials that carry electricity without resistance at temperatures well above absolute zero (158: 330*).

* Tissue engineers created a crude artificial nose and an artificial thymus by growing cells on scaffolds of carbon and polymer foam, respectively (157: 149; 158: 63).

* Bringing nearer to fruition microchips that process light, instead of electrons, fabrication advances improved the properties of artificial optical materials known as photonic crystals (157, 399; 158: 159).