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SACHEM Launches 2-D HPLC e-Learning Program.


New e-Learning Program Teaches Scientists How to Better Analyze and Prove Product Purity Through Greater Sensitivity and Precision in Identification of Trace Components

AUSTIN, Texas -- SACHEM sa·chem  
n.
1.
a. A chief of a Native American tribe or confederation, especially an Algonquian chief.

b. A member of the ruling council of the Iroquois confederacy.

2.
 announced today the launch of a new displacement chromatography e-Learning program. With the growing popularity of SACHEM's Isolis[TM] displacers, SACHEM is offering scientists worldwide the ability to learn more about applying displacement chromatography in two dimensional High Performance Liquid Chromatography High-performance liquid chromatography (HPLC) is a form of column chromatography used frequently in biochemistry and analytical chemistry. It is also sometimes referred to as high-pressure liquid chromatography.  (2-D HPLC HPLC high-performance liquid chromatography.

HPLC

high performance liquid chromatography.

HPLC High-performance liquid chromatography Lab instrumentation A highly sensitive analytic method in which analytes are placed
).

Two-dimensional HPLC facilitates the separation of complex mixtures by using different chromatography modes as sequential steps. By using displacement chromatography in the first dimension, one can better analyze and prove product purity through greater sensitivity and precision in identification of trace components. Moreover, in oligonucleotide Oligonucleotide

A deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequence composed of two or more covalently linked nucleotides. Oligonucleotides are classified as deoxyribooligonucleotides or ribooligonucleotides.
, proteomics and other similar applications, this technique is a measurable superior technique to detect minor component biomolecules This page aims to list articles on Wikipedia that describe particular biomolecules or types of biomolecules.

This list is not necessarily complete or up to date - if you see an article that should be here but isn't (or one that shouldn't be here but is), please update the page
 of interest. 2-D HPLC using displacement chromatography in the first dimension addresses challenges in characterization, process control, process optimization Process optimization is the practice of making changes or adjustments to a process, to get results.

Optimization is the use of specific techniques to determine the most cost effective and efficient solution to a problem or design for a process.
, biomarker analysis, QBD QBD Quality by Design (FDA Initiative)
QBD Quasi-Birth-And-Death (process)
QBD Queens Bench Division
QBD QoS Bearer Descriptor
QBD QuickBooks Dos
QBD Quantum Barrier Device
 programs and proteomics.

This 10-minute, customized, simulation-based program enables users to gain a deeper understanding of 2-D HPLC using displacement chromatography. In the first dimension one uses displacement chromatography to concentrate low abundance materials in discrete transition zones within the displacement train. This first step removes 95% of main component interference without affinity resins or prior knowledge of component identity. The second chromatography step is then used to analyze these enriched samples.

"The results of 2-D HPLC with displacement chromatography are impressive and this new e-Learning course illustrates the power of integrating this method into critical analytical analysis," remarks Rosemary Hoffman, Director, Biotechnology Solutions Group at SACHEM. "Proof of product purity is critical to biopharmaceutical companies and regulatory agencies regulatory agency

Independent government commission charged by the legislature with setting and enforcing standards for specific industries in the private sector. The concept was invented by the U.S.
. This technique enables a significantly improved approach to meeting this important challenge."

SACHEM offers specifically designed displacers, regeneration agents and simple, easy-to-use protocols. For additional support, SACHEM provides the technical expertise to make this method easy enough to use everyday. Isolis System[TM] products can be purchased at www.sachemstore.com.

The e-Learning program is available on SACHEM's website at www.sacheminc.com.

About SACHEM:

SACHEM, Inc. delivers highly pure, precise and innovative chemical solutions designed to solve the most demanding and challenging applications. For over 50 years SACHEM has provided chemical solutions and services to customers in key markets including electronics, biotechnology, starch modification, polymers, catalysts, pharmaceutical and agricultural chemicals. Based in Austin, Texas, SACHEM's expanding worldwide operations include manufacturing and research facilities in North America North America, third largest continent (1990 est. pop. 365,000,000), c.9,400,000 sq mi (24,346,000 sq km), the northern of the two continents of the Western Hemisphere. , Europe and Asia with a global service network and presence spanning over 30 countries. For more information about SACHEM, Inc. please view www.SACHEMINC.com.
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Publication:Business Wire
Date:Sep 8, 2008
Words:424
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