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Routine Blood Filtration Now on German Horizon Says Pall Corporation, World Leader in Blood Filtration.


Business Editors, Health/Medical Writers

EAST HILLS, N.Y.--(BUSINESS WIRE)--March 21, 2000

Germany, which currently filters less than 25% of its four million plus blood donations “Give blood” redirects here. For other uses, see Give blood (disambiguation).
Blood donation is a process by which a blood donor voluntarily has blood drawn for storage in a blood bank, generally for subsequent use in a blood transfusion.
 intends to filter all of them to remove leukocytes. The Paul-Ehrlich-Institut announced that it has the support of the Federal Ministry of Health to proceed with plans to improve the safety of Germany's blood supply using leukocyte reduction leukocyte reduction Leukocyte depletion, leukodepletion Transfusion medicine Any technique that ↓ WBCs in transfused blood products–eg, RBCs, platelets; LR to < 5 x 108 virtually eliminates nonhemolytic (immunologic) transfusion reactions.  technology. Support from Germany's Health Ministry paves the way for mandatory filtration of all plasma, red cells and platelet products.

With its decision to filter all donor blood, Germany becomes the twenty-third nation committed to universal blood filtration. Several of these counties have mandated routine blood filtration as a matter of public policy. Among them are France, Canada and the United Kingdom. Germany is expected to join this list. Many others, including the US, Japan, and Austria are moving without mandate to filter all donor blood.

In the US, the FDA's Blood Products Advisory Committee, an independent board upon which the Federal Government relies to furnish expert advice, unanimously agreed that, "the benefit to risk ratio associated with leukoreduction is sufficiently great to justify routine leukoreduction of all non-leukocyte transfusion blood components...." Since this September, 1998 recommendation, blood filtration in the US has nearly doubled from about 16% to about 30% today. The American Red Cross American Red Cross: see Red Cross. , which manages about 45% of the US blood supply, has publicly stated its intention to filter all of its blood collections by the end of the year.

The Paul-Ehrlich-Insititut is an independent Federal agency within the jurisdiction of the German Federal Ministry of Health. It is responsible for licensing and batch control (1) The management of documents or electronic media that have been grouped, cataloged and are waiting for processing. See batch processing.

(2) An industrial control application that makes products in vats and tanks rather than in a continuous series of processes that
 of drugs for human and veterinary use. In 1994, it assumed additional responsibility for all blood products calling them "a particularly precarious group of drugs carrying a sizeable risk of viral contamination and variations in efficacy." Much like the U.S. Food and Drug Administration, the Institut is authorized to issue directives to pharmaceutical companies and transfusions centers to prevent or reduce risks associated with biological products. The Paul-Ehrlich-Institut is a strong proponent of leukocyte reduction as a means to enhanced blood safety.

Pall Corporation Pall Corporation NYSE: PLL, formerly Micro Metallic Company, is an East Hills, New York based global business in the diverse field of filtration, separations and purification. Total revenues for fiscal 2006 were $2 billion, with over 11,000 employees and $56.  (NYSE NYSE

See: New York Stock Exchange
:PLL PLL - phase-locked loop ), the market leader, offers the broadest range of advanced blood filtration products and the support services support services Psychology Non-health care-related ancillary services–eg, transportation, financial aid, support groups, homemaker services, respite services, and other services  to help blood centers meet the challenges of implementing routine, high volume, blood filtration. The Company is prepared to meet the growing requirements of its customers for products, logistics and regulatory support. Pall reported fiscal 1999 blood filter sales in excess of $185 million and sales for the first half of fiscal 2000 have increased 20%, reflecting the increased worldwide demand. The world market for blood filters is estimated at $1.2 billion.

Clinical and Economic Benefits of Blood Filtration:

Every three seconds someone needs blood. It is now widely accepted that leukocytes in donor blood can cause serious medical complications. Clinical studies have shown that leukocyte reduction by filtration reduces transfusion-related suppression of the immune system immune system

Cells, cell products, organs, and structures of the body involved in the detection and destruction of foreign invaders, such as bacteria, viruses, and cancer cells. Immunity is based on the system's ability to launch a defense against such invaders.
 and helps protect against post-surgical infection. Based on medical risk and clinical benefits of filtration, hospitals and blood centers have been converting to 100% filtered blood. The economics of blood filtration are equally compelling. Patients who receive filtered blood typically spend two to six less days in the hospital, require fewer antibiotics and diagnostic tests and less time with medical personnel.

With annual sales over $1 billion, Pall Corporation is based in East Hills, New York East Hills is a village in Nassau County, New York on the North Shore of Long Island. It is considered part of the Greater Roslyn area, which is anchored by the Village of Roslyn. As of the United States 2000 Census, the village population was 6,842. , USA and operates directly in about 30 countries. Pall Corporation provides innovative solutions to complex filtration and separations problems in four major markets: Medical, BioPharmaceuticals, Aeropower and Fluid Processing. The Company's shares are listed on the New York Stock Exchange New York Stock Exchange (NYSE)

World's largest marketplace for securities. The exchange began as an informal meeting of 24 men in 1792 on what is now Wall Street in New York City.
 (PLL). Further information is available on the Company's web site at http://www.pall.com.
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Publication:Business Wire
Date:Mar 21, 2000
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