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Revolutionary L-Hydantoinase Enzymatic Process Wins Degussa the 2003 Frost & Sullivan Product of the Year Award.


Business Editors

LONDON--(BUSINESS WIRE)--Dec. 18, 2003

The 2003 Frost & Sullivan Product of the Year Award for the Fine Chemicals Industry is awarded to Degussa for its L-hydantoinase enzymatic process for single-step production of L-amino acids used in the pharmaceutical, food and chemical industry.

Prior to hydantoinase technology, non-natural L-amino acids could only be obtained through a complex chemical process that consumed excessive amounts of energy and chemicals. Backed by an established record of product innovation, the award recipient successfully responded to consumer demand for a simpler, more effective process.

Collaborating with Prof. C. Syldatk, a pioneer in the hydantoinase field at the University of Stuttgart The University of Stuttgart (German Universität Stuttgart) is a university located in Stuttgart, Germany. It was founded in 1829 and is organized in 10 faculties. , and Prof. F. H. Arnold, a chemistry professor at Caltech, Degussa designed and developed a highly versatile platform technology based on tailor-made whole cell biocatalyst bi·o·cat·a·lyst  
n.
A substance, especially an enzyme, that initiates or modifies the rate of a chemical reaction in a living body; a biochemical catalyst.



bi
 that convert 5-monosubstituted hydantoins into either an L- or D-amino acids in one pot with up to 100 percent chemical and optical yield.

"Proteinogenic L-amino acids made in this way have enormous advantages. The process is easy, efficient and costs involved are minimal which has given Degussa enormous advantages over its competitors," explains Frost & Sullivan Research Analyst, Dr. Raju Adhikari.

Degussa has already won significant contracts to manufacture amino acids amino acid (əmē`nō), any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.  using L-hydantoinase enzymatic process and has several project tie-ups with both big and small pharmaceutical companies. The company now possesses a clear competitive advantage in the market.

Strong in-house R&D supported by an over-$47 million budget has underpinned Degussa's trailblazing trail·blaz·ing  
adj.
Suggestive of one that blazes a trail; setting out in a promising new direction; pioneering or innovative: trailblazing research; a trailblazing new technique. 
 product development efforts. The visionary "Project House System" has a strategic research orientation and is deeply involved in exploring technologies with future potential. It has encouraged closer interaction of different business units for project discussion and growth-oriented R&D planning.

"Degussa's success is not only based on its good track record on traditional manufacturing applications, but also on solid R&D and its prestigious background of being an innovator," notes Dr. Adhikari. "Degussa will continue to be a leader in the field."

Selection of the Frost & Sullivan award A Sullivan Award may refer to:
  • Algernon Sydney Sullivan Award or Mary Mildred Sullivan Award; awarded at 29-grantee institutions of the Algernon Sydney Sullivan Foundation.
 winner was based on extensive primary research among market participants The term market participant is used in United States constitutional law to describe a U.S. State which is acting as a producer or supplier of a marketable good or service. When a state is acting in such a role, it may permissibly discriminate against non-residents. , customers and suppliers as well as on secondary and technology research. Industry participants were ranked based on specific measurement criteria that included degree of product innovation, product price and quality, estimated market penetration Noun 1. market penetration - the extent to which a product is recognized and bought by customers in a particular market
penetration - the act of entering into or through something; "the penetration of upper management by women"
 rate, acceptance of the product by intended users and competitive advantage of new product in industry.

By excelling against these criteria, and emerging as "the company that has best demonstrated the ability to develop and/or advance products with more innovative capabilities than competing vendors and products," Degussa was the undisputed choice for the 2003 Frost & Sullivan Product of the Year Award.

A photo regarding the awards presentation to Degussa can be downloaded from the following Web site:

http://www.frost.com/prod/servlet/press-release.pag?docid=8810158

About Frost & Sullivan

Frost & Sullivan is a global leader in international strategic growth consulting. Frost & Sullivan Awards are presented to companies that demonstrate excellence in their industry, commending the diligence, commitment and innovative business strategies required to advance in the global marketplace.

Frost & Sullivan rigorously analyzes specific criteria to determine award recipients in a vast variety of industries and landscapes. Founded in 1961, Frost & Sullivan is headquartered in San Jose San Jose, city, United States
San Jose (sănəzā`, săn hōzā`), city (1990 pop. 782,248), seat of Santa Clara co., W central Calif.; founded 1777, inc. 1850.
, Calif., with offices located worldwide. For further information, visit www.frost.com.

About Degussa

Degussa is a multinational corporation multinational corporation, business enterprise with manufacturing, sales, or service subsidiaries in one or more foreign countries, also known as a transnational or international corporation. These corporations originated early in the 20th cent.  consistently aligned to highly profitable specialty chemistry. With sales of 11.8 billion Euro and a workforce of some 48,000, it is Germany's third-largest chemical company and the world market leader in specialty chemicals A Specialty chemical is a chemical produced for a specialized use. They are produced in lower volume than bulk chemicals, of which petrochemicals, made from oil feedstocks, are the most common. However, both are produced in a chemical plant. . In fiscal 2002, the corporation generated operating profits Operating profit (or loss)

Revenue from a firm's regular activities less costs and expenses and before income deductions.


operating profit

See operating income.
 (EBIT EBIT

See: Earnings Before Interest and Taxes


EBIT

See earnings before interest and taxes (EBIT).
) of more than 900 million Euro. Degussa's core strength lies in highly-effective system solutions that are tailored to the requirements of its customers in over 100 countries throughout the world. Degussa's activities are led by the vision "Everybody benefits from a Degussa product -- every day and everywhere."
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Publication:Business Wire
Date:Dec 18, 2003
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