Printer Friendly
The Free Library
14,679,288 articles and books
Member login
User name  
Password 
 
Join us Forgot password?

Results of Pre-Clinical Investigations of Ceragenix's Novel Antibiotic to Be Presented at Major International Scientific Meeting on Infectious Disease.


DENVER -- Ceragenix Pharmaceuticals, Inc. ("Ceragenix") (OTCB:CGXP) today announced that five poster presentations on the efficacy of its Cationic cationic

having qualities dependent on having free cations available.


cationic detergents
are wetting agents that disrupt or damage cell membranes, denature proteins and inactivate enzymes.
 Steroid Antbiotic ("CSA (1) (Canadian Standards Association, Toronto, Ontario, www.csa.ca) A standards-defining organization founded in 1919. It is involved in many industries, including electronics, communications and information technology. ") technology have been accepted for presentation at the upcoming annual meeting of the American Society for Microbiology's Interscience Conference on Antimicrobial Agents and Chemotherapy Antimicrobial Agents and Chemotherapy (print-ISSN 0066-4804, CODEN AMACCQ; canceled ISSN 0074-9923, canceled CODEN AACHAX) is an academic journal published by the American Society for Microbiology.  ("ICAAC ICAAC Interscience Conference on Antimicrobial Agents and Chemotherapy
ICAAC Iowa Community College Athletic Conference
") to be held September 20-24th in New Orleans, Louisiana. The ICAAC annual meeting attracts over 12,000 physicians, researchers and other healthcare professionals from around the world to foster worldwide solutions to the problem of infectious disease.

Ceragenix's CSA technology is a potential solution to the growing threat of multidrug-resistant bacterial infections. The CSAs are synthesized small molecules that mimic the activity of the much larger naturally occurring antimicrobial peptides, such as LL-37, which form part of the human body's innate immune system
See also:  and
The innate immune system comprises the cells and mechanisms that defend the host from infection by other organisms, in a non-specific manner.
. Ceragenix is pursuing development of the CSAs for use in a topical preparation to control bacterial infections in burn victims and as a thin-film coating to prevent bacterial infection of in-dwelling medical devices such as urinary catheters, among other indications. The five poster presentations accepted for presentation at ICAAC are:

Poster #3402: "Activity of a Novel Cationic Steroid Antimicrobial (CSA-13) Against Staphylococcus aureus and Bacterial Species Associated with Infection in Cystic Fibrosis Patients";

Poster # 3460: "Activity of a Novel Cationic Steroid Antimicrobial (CSA-13) Targeting Aerobic and Facultative Gram-negative Bacilli, Gram-Positive Anaerobes and Select Agent Surrogate Strains";

Poster #3398: "Thin Film Containing a Cationic Steroid Antibiotic Displays Bactericidal bactericidal /bac·te·ri·ci·dal/ (bak-ter?i-si´d'l) destructive to bacteria.
Bactericidal
An agent that destroys bacteria (e.g.
 Activity";

Poster # 3467: "Topical Applications of Cationic Steroid Antimicrobial (CSA-13) in Treatment of Burn Wound Colonization by Pseudomonas aeruginosa in Burned Mice"; and

Poster #554: "Kill Kinetics of CSA-13 and Comparators Against Staphylococci with Raised Glycopeptide MICs."

Steven Porter, Chairman and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Ceragenix stated: "We are very pleased that all five poster presentations submitted by investigators to ICAAC have been accepted for presentation at this international conference. We would like to thank Drs. Bogdanovich and Appelbaum at the Hershey Medical Center for performing the kill kinetics analysis for Poster #554; Dr. El-Azizi at Southern Illinois University Southern Illinois University, main campus at Carbondale; state supported; coeducational; est. 1869, opened 1874 as a normal school, renamed 1947. It has a center for archaeological investigation and a fisheries research laboratory. There is also a campus at Edwardsville.  for his research and poster submission #3467; Drs. Ron Jones and Tom Fritsche of JMI Labs for their testing of CSA-13 in Posters # 3402 and 3460 and Dr. Henry F. Chambers (UCSF UCSF University of California at San Francisco ) for his overall guidance and for supplying clinical isolates of Community-Associated Methicillin Resistant Staphylococcus Aureus ("MRSA MRSA Methicillin-resistant Staphylococcus aureus. See MARSA. ") for testing in Poster #3402. Our special thanks to Dr. Paul B. Savage at BYU who developed this promising technology and who contributed to all of these poster presentations. We look forward to sharing the results of these studies with the scientific community at the annual ICAAC meeting."

About Ceragenix

Ceragenix is a development-stage biopharmaceutical company focused on dermatology and infectious disease. Ceragenix's patented Barrier Repair Technology, invented by Dr. Peter Elias and licensed from the University of California The University of California has a combined student body of more than 191,000 students, over 1,340,000 living alumni, and a combined systemwide and campus endowment of just over $7.3 billion (8th largest in the United States). , is the platform for the development of two prescription topical creams -- EpiCeram(TM) and NeoCeram(TM) -- that form human-identical skin barriers. Defects in the skin's barrier function play critical roles in the pathogenesis of skin diseases such as eczema, irritant contact dermatitis irritant contact dermatitis Occupational dermatology A form of CD that usually affects the hands and arms, caused by acids, alkalis; the intensity of skin response reflects intrinsic nature of the chemical, its concentration, and duration of contact Clinical , and other common skin disorders. The Company's patented Cationic Steroid Antibiotic (CSA) technology provides the basis for its novel antimicrobial medical device coating that may be attached to various medical devices to provide potentially long duration antimicrobial activity. Ceragenix also plans to develop CSAs for use as topical and systemic antibiotic therapies in the treatment of skin infections (MRSA), burn wound infections, eye infections, and other indications.

Forward-Looking Statements

This press release may contain forward-looking statements. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995 provides a safe harbor for forward-looking statements. These forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied by such forward-looking statements, including, but not limited to, the following: the ability of the company to raise sufficient capital to finance its planned activities, receiving the necessary marketing clearance approvals from the FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
, successful clinical trials of the company's planned products, the ability of the company to commercialize its planned products, market acceptance of the company's planned products, and the company's ability to successfully compete in the marketplace. Although management believes that the assumptions underlying the forward-looking statements are reasonable, any of the assumptions could prove inaccurate and, therefore, there can be no assurance that the forward-looking statements will prove to be accurate. In light of the significant uncertainties inherent in the forward-looking statements, the inclusion of such information should not be regarded as a representation by the company or any other person that the objectives and plans of the company will be achieved. For further information, please see the company's filings with the SEC, including its Forms SB-2, 10-KSB, 10-QSB, and 8-K. The company assumes no obligation to update its forward-looking statements to reflect actual results or changes in factors affecting such forward-looking statements.
COPYRIGHT 2005 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

 Reader Opinion

Title:

Comment:



 

Article Details
Printer friendly Cite/link Email Feedback
Publication:Business Wire
Date:Jul 19, 2005
Words:802
Previous Article:Interlink Global Applies for Important CLEC License.
Next Article:Interpublic Names Chief Financial Officer; Frank Mergenthaler Brings Strong Operational Finance Experience in Media and Entertainment Industries, Top...



Related Articles
Ceragenix's Lead Compounds Show Anti-Angiogenic Activity; National Cancer Institute Accepts Compounds for Testing.
Professor Sean P. Gorman Joins Ceragenix Pharmaceuticals' Scientific Advisory Board; World Renowned Expert in Medical Device Coatings.
Professor Richard Gallo, Leading Research Dermatologist, Joins Ceragenix's Scientific Advisory Board.
Ceragenix Signs Letter of Intent with the Centers for Disease Control and Prevention (CDC) to Enter into a Cooperative Research and Development...
AVEXA/CSIRO COLLABORATE ON TREATMENTS FOR INFECTIOUS DISEASES.
Forum Alert: Ceragenix Pharmaceuticals, Inc. will Present at the Informed Investors Biotechnology & Healthcare Investor Forum at The Hyatt Regency in...
In Vitro Study Results Show Ceragenix's Lead Antibiotic Compound Has Greater Bactericidal Activity against Potentially Lethal Bacterial Infections...
Ceragenix Presents Positive Data on its Novel Antimicrobial Medical Device Coating at International Conference on Infectious Diseases.
Ceragenix Pharmaceuticals Appoints Dr. Donald Leung to its Scientific Advisory Board.
Dr. Michael Rybak Joins Ceragenix's Scientific Advisory Board.

Terms of use | Copyright © 2009 Farlex, Inc. | Feedback | For webmasters | Submit articles