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Research and Markets: an Evaluation of the Capabilities, Strengths, Weaknesses, and Expectations of Leading Assays and Assay Technologies.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c8592) has announced the addition of A Guide to Assay Development to their offering.

This Guide thoroughly evaluates the capabilities, strengths, weaknesses, and expectations of leading assays and assay technologies.

Assay development is often time consuming and frustrating frus·trate  
tr.v. frus·trat·ed, frus·trat·ing, frus·trates
1.
a. To prevent from accomplishing a purpose or fulfilling a desire; thwart:
. But reliable, robust assays are key to every phase of pharmaceutical development. This Guide to Assay Development provides critical information to speed and simplify the development and optimization optimization

Field of applied mathematics whose principles and methods are used to solve quantitative problems in disciplines including physics, biology, engineering, and economics.
 of most technologies. This Guide eliminates the tendency to "reinvent the wheel (jargon) reinvent the wheel - To design or implement a tool equivalent to an existing one or part of one, with the implication that doing so is silly or a waste of time. This is often a valid criticism. " by providing valuable tips that incorporate the author's many years of hands-on experience in the field.

This Guide provides the information necessary to select and develop the appropriate assay for the task at hand, including:

--The most common and rapidly-growing assays in the drug discovery and drug development industries.

--Charts and tables cut through the sales hype hype 1   Slang
n.
1. Excessive publicity and the ensuing commotion: the hype surrounding the murder trial.

2.
 and facilitate comparisons of different assay types.

--Tips and tricks learned over 15 years of professional experience and collaborative work in laboratory assays.

--The often neglected topics of biological sample matrix and high-volume data analysis.

--Step-by-step instructions and checklists for assay optimization, validation, automation, scale-up, and miniaturization min·i·a·tur·ize  
tr.v. min·i·a·tur·ized, min·i·a·tur·iz·ing, min·i·a·tur·iz·es
To plan or make on a greatly reduced scale.



min
.

--Emerging platforms, formats, and technologies for high-throughput screening High-throughput screening (HTS), is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry. Purpose and method  (HTS HTS Heights
HTS Harmonized Tariff System
HTS High Throughput Screening (biomolecular assay screening)
HTS High-Throughput Screening (Pharmaceutical Industry)
HTS Harmonized Tariff Schedule
) and ultra-high-throughout screening (UHTS UHTS Ultrahigh-Throughput Screening (Pharmaceutical Industry)
UHTS Universal Hydraulic Test Stand
).

--Detailed comparisons of technologies designed to help scientists determine the best format to meet their assay needs.

--Lists of instrument manufacturers and supply vendors-including original references and historical developments, with resources for finding detailed modern laboratory recipes.

The following professionals involved in drug discovery, screening, lead generation, and assay technology will greatly benefit from this Guide:

Directors, Lab Managers, Group Leaders, Senior Scientists, Principal Scientists, Project Managers, Heads of Research & Development, Quality Control Managers, and more

This Guide Will Answer the Following Questions:

--How does a scientist determine the best assay for a particular application?

--What questions must be asked and answered during assay development?

--What steps are involved in optimization and validation of an assay?

--How can a scientist determine that an assay is fully optimized, sufficiently validated, and ready for full-scale operation?

--How can controls be used to provide the earliest warning of assay problems?

--How does sample throughput and assay miniaturization really affect data quality and reagent reagent /re·a·gent/ (re-a´jent) a substance used to produce a chemical reaction so as to detect, measure, produce, etc., other substances.

re·a·gent
n.
 consumption?

--Will migrating to a higher-density microplate format improve throughput?

--How do state-of-the-art assay instruments fail during normal operation, and what can be done to minimize failure and the impact of failure on operations?

--What universal considerations are critically important for every assay?

For more information visit http://www.researchandmarkets.com/reports/c8592
COPYRIGHT 2004 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2004, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Nov 2, 2004
Words:418
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