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Research and Markets: Renal Cell Carcinoma and Multiple Myeloma: Leaders Emerge, But Plenty of Room for Numerous Competitors - ASCO Review Part I - A Summary of Highlights Presented At the ASCO 2006 Annual Meeting.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c42593) has announced the addition of Financial Markets Research: ASCO ASCO American Society of Clinical Oncology
ASCO Association of Schools and Colleges of Optometry (since 1941; Rockville, Maryland)
ASCO Australian Standard Classification of Occupations
ASCO Automatic Switch Company
 Review Part I - A Summary of Highlights Presented at the ASCO 2006 Annual Meeting to their offering.

ASCO features key presentations in the oncology area, and is generally the most important week of the year for oncology. Presented are comments on the most important events at the 2006 conference.

Scope of this title:

* Provides a summary of highlights presented at ASCO 2006 on Friday June 2, 2006 through Sunday June 4, 2006

* Drugs covered include Amgens denosumab (AMG-162), AstraZenecas Zactima (vandetanib/ZD6474), and Bristol-Myers Squibbs Bristol-Myers Squibb (NYSE: BMY), colloquially referred to as BMS, is a pharmaceutical corporation, formed by a 1989 merger between pharmaceutical companies Bristol-Myers Company, founded in 1887 by William McLaren Bristol and John Ripley Myers in Clinton, NY (both were  Sprycel (dasatinib)

Highlights of this title:

* GlaxoSmithKlines lapatinib should represent a new standard of care for patients for HER2+ metastatic Metastatic
The term used to describe a secondary cancer, or one that has spread from one area of the body to another.

Mentioned in: Coagulation Disorders


metastatic

pertaining to or of the nature of a metastasis.
 breast cancer patients that have progressed after Herceptin. Furthermore, the strength of lapatinib in a post-Herceptin setting supports the development of this drug in earlier settings.

* Following dasatinibs favorable review by an FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 panel, we believe data presented at ASCO is likely to have a very positive impact on the rate of uptake of dasatinib.

* Advantage in the renal cell carcinoma renal cell carcinoma
 or hypernephroma

Malignant tumour of the cells that cover and line the kidney. It usually affects persons over age 50 who have vascular disorders of the kidneys. It seldom causes pain, unless it is advanced.
 market has shifted to PFEs Sutent after data comparing BAY/ONXXs Nexavar to interferon in the front-line setting was not ready to be presented, thus opening the door for Sutent.

Reasons to read this report:

* Identify the most important events that occurred at ASCO 2006

* Understand the impact of key data presentations on the potential future dynamics of the oncology market

The contents contained inside this report include:

Summary

Renal cell carcinoma and multiple myeloma multiple myeloma

A malignant proliferation of abnormal plasma cells that populate the marrow-containing bones of the body. The affected plasma cells produce myeloma protein, a monoclonal antibody that replaces normal antibodies in the blood, thereby increasing susceptibility
: leaders emerge, but plenty of room for numerous competitors

ASCO Coverage

Key highlights

Highlights In Renal Cell Carcinoma

Focus on renal cell carcinoma continues at ASCO

Sequential targeted therapy looks promising, but case against EGFR EGFR Epidermal Growth Factor Receptor (a kinase enzyme)
EGFR Estimated Glomerular Filtration Rate
 inhibition builds

Reports of "failure" are misleading, but Nexavar yet to prove survival benefit

Renal cell summary: Sutent and temsirolimus step forward while Nexavar stands still

Highlights In Multiple Myeloma

Three agents offer significant clinical benefit

Thalomid-containing regimens now have time to progression and survival benefit data

Thalomid data in newly diagnosed elderly patients impressive but unlikely to have major impact on treatment

Median overall survival for Revlimid in relapsed and refractory refractory

Material that is not deformed or damaged by high temperatures, used to make crucibles, incinerators, insulation, and furnaces, particularly metallurgical furnaces.
 disease recently reached

Uncertainty surrounds Revlimids efficacy in Thalomid failures

With risk factors for thromboembolism thromboembolism /throm·bo·em·bo·lism/ (-em´bo-lizm) obstruction of a blood vessel with thrombotic material carried by the blood from the site of origin to plug another vessel.

throm·bo·em·bo·lism
n.
 identified, Revlimid can be used more safely

Optimal treatment algorithm remains undetermined - which treatment will be used upfront?

Appendix

Our Healthcare

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For more information visit http://www.researchandmarkets.com/reports/c42593

Source: Datamonitor
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Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Sep 25, 2006
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