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Regeneron obtains United States patent.

Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) has patented methods of creating mutations in genomic exons by inserting introns into the genomic exons via homologous recombination. Also, methods are provided for introducing modifications into genomic exons by inserting introns into the genomic exons via homologous recombination such that a mature mRNA transcript produced from a genomic region of the genome comprising the genomic exon does not contain the modification are provided. The methods provide for a rapid method for introducing mutations and/or modifications of any type into a mammalian cell genome. (US 7,205,148)
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Title Annotation:inserting introns into the genomic exons through homologous recombination; Regeneron Pharmaceuticals Inc.
Publication:BIOTECH Patent News
Article Type:Brief article
Date:Apr 1, 2007
Words:94
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