Recent Research on Leukemia Has Revealed 85 Drug Candidates in Phase II or III Stage of Development and More Than 50 Companies Are Involved In the Development of These Drugs.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c43821) has announced the addition of Leukemia - A Therapeutic & Competitive Insight to their offering. Leukemia includes a broad variety of histological separate disorders which make the leukemia market segmented. And even though a high level of unmet medical need, together with its dependence on chemotherapy, leukemia has not historically been the focus of significant R&D investment for emerging drugs in the pharmaceutical industry. This has now clearly changed with the launch of Novartis' Gleevec (imatinib mesylate imatinib mesylate Warning - Hazardous drug! Gleevec, Glivec (UK) Pharmacologic class: Protein-tyrosine kinase inhibitor Therapeutic class: Antineoplastic ) for chronic myeloid leukemia myeloid leukemia n. See myelogenous leukemia. (CML 1. CML - A query language. ["Towards a Knowledge Description Language", A. Borgida et al, in On Knowledge Base Management Systems, J. Mylopoulos et al eds, Springer 1986]. 2. CML - Concurrent ML. ), which is presenting the industry with proof that development within the leukemia market produces lucrative returns. Gleevec saw sales rise 32 percent to $2.2 billion during 2005. Consequently, the historical general conception that relatively low prevalence diseases, has been insufficient in size to allow companies to quickly regain their investment is clearly out of date. In this perspective enhanced development is expected. Research and analysis highlights In the report "Leukemia - A Therapeutic & Competitive Insight" The author does not only describe and analyze the latest years of progress in four different market segments; CLL CLL abbr. chronic lymphocytic leukemia CLL, n.pr See leukemia, chronic lymphocytic. CLL 1. Chronic lymphocytic leukemia 2. Cholesterol-lowering lipid , CML ALL and AML AML - A Manufacturing Language , but also provide a insight and framework to understand the complex field of leukemia therapeutics. In this report, the author provides one of the most comprehensive coverage of the R&D trends to set the future leukemia marketplace. The author presents both an overview and a detailed description on the progress of key drugs in Phase III Noun 1. phase III - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA and II development, together with general descriptions on drugs and targets. The research has identified 85 drug candidates in phase II or III stage of development and more than 50 companies are involved in the development of these drugs. Among these drugs you can clearly see substantial progress while others have failed. There will be a more intense competition in several of the leukemic sub-markets and current treatments will be changed for the benefit of more innovative therapies. Scope of this report Thorough examination of status and impact of several novel drugs in development Discussion of the challenges in current and future treatment strategies Anticancer pipeline of most companies in the field Key reasons to read this report * Explore the strengths and weaknesses associated with compounds in clinical development. Scientific rationale for most novel therapeutics in leukemia R&D, and the results of clinical trials to date * Gain insight into the current challenges and commercial opportunities associated with leukemia therapy * More than 130 high quality references Some of the drugs included in this analysis AG-858, Alemtuzumab, AP23573, Atra, Avastin, BAY 43-9006, CEP-701, Ceplene, Clofarabine, Cloretazine, Decitabine, FK228, Flavopiridol, Gemtuzumab, Genasense, Gvax, Imatinib, OSI-461, PKC PKC Protein Kinase C (biochemistry) PKC Public Key Cryptography PKC Public Key Certificate PKC PaKua Chang (Chinese martial art) PKC Paroxysmal Kinesigenic Choreoathetosis 412, PTK PTK Phi Theta Kappa PTK Protein Tyrosine Kinase (insulin receptor) PTK Polskiego Towarzystwa Kardiologicznego (Polish Cardiac Society) PTK Phototherapeutic Keratectomy PTK Pairwise Transient Key 787, Rituximab, SU5416, Troxacitabine, Valspodar, VELCADE, Xcytrin and Zarnestra Content Outline: 1 Executive Summary 2 Cancer Highlights 3 Methodology 4 Table of Contents 5 Introduction 6 Current Treatment Strategies 7 Progress in Current Treatment Strategies 8 Key Therapeutic Strategies for Future Therapies 9 Competitive Landscape in Drug Development: The Late Stage Pipeline 10 Current Drug Development: The Early Stage Pipeline 13 Drug Index 14 Company Index 4.1 List of Boxes 4.2 List of Tables Some of the companies included in this analysis: Amgen, Antigenics, Bayer, Bioenvision, Biogen Idec, BTG BTG BIT (Built-In Test) Target Generator BTG Bridging the Gap BTG British Technology Group BtG Betreuungsgesetz (Germany) BTG Biomass Technology Group BV BTG Begbies Traynor Group , Cell Genesys, Cephalon Ceph´a`lon n. 1. (Zool.) The head. , Cyclacel Group (Cyclacel), Exelixis, Genta, GlaxoSmithKline, Johnson & Johnson, Millennium, Novartis, Pharmacyclics, PDL See page description language. 1. PDL - Page Description Language. 2. PDL - Program Design Language. 3. PDL - Push Down List. 4. PDL - Dave Lebling, one of the co-authors of Zork. BioPharma, Schering-Plough, SuperGen, Vion Pharmaceuticals and Wyeth For more information visit http://www.researchandmarkets.com/reports/c43821 |
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