Printer Friendly
The Free Library
5,665,953 articles and books
Member login
User name  
Password 
 
Join us Forgot password?

Recent Research on Leukemia Has Revealed 85 Drug Candidates in Phase II or III Stage of Development and More Than 50 Companies Are Involved In the Development of These Drugs.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c43821) has announced the addition of Leukemia - A Therapeutic & Competitive Insight to their offering.

Leukemia includes a broad variety of histological separate disorders which make the leukemia market segmented. And even though a high level of unmet medical need, together with its dependence on chemotherapy, leukemia has not historically been the focus of significant R&D investment for emerging drugs in the pharmaceutical industry.

This has now clearly changed with the launch of Novartis' Gleevec (imatinib mesylate imatinib mesylate Warning - Hazardous drug!

Gleevec, Glivec (UK)

Pharmacologic class: Protein-tyrosine kinase inhibitor

Therapeutic class: Antineoplastic

) for chronic myeloid leukemia myeloid leukemia
n.
See myelogenous leukemia.
 (CML 1. CML - A query language.

["Towards a Knowledge Description Language", A. Borgida et al, in On Knowledge Base Management Systems, J. Mylopoulos et al eds, Springer 1986].
2. CML - Concurrent ML.
), which is presenting the industry with proof that development within the leukemia market produces lucrative returns. Gleevec saw sales rise 32 percent to $2.2 billion during 2005. Consequently, the historical general conception that relatively low prevalence diseases, has been insufficient in size to allow companies to quickly regain their investment is clearly out of date. In this perspective enhanced development is expected.

Research and analysis highlights

In the report "Leukemia - A Therapeutic & Competitive Insight" The author does not only describe and analyze the latest years of progress in four different market segments; CLL CLL
abbr.
chronic lymphocytic leukemia


CLL,
n.pr See leukemia, chronic lymphocytic.

CLL 1. Chronic lymphocytic leukemia 2. Cholesterol-lowering lipid
, CML ALL and AML AML - A Manufacturing Language , but also provide a insight and framework to understand the complex field of leukemia therapeutics. In this report, the author provides one of the most comprehensive coverage of the R&D trends to set the future leukemia marketplace. The author presents both an overview and a detailed description on the progress of key drugs in Phase III Noun 1. phase III - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA  and II development, together with general descriptions on drugs and targets. The research has identified 85 drug candidates in phase II or III stage of development and more than 50 companies are involved in the development of these drugs. Among these drugs you can clearly see substantial progress while others have failed. There will be a more intense competition in several of the leukemic sub-markets and current treatments will be changed for the benefit of more innovative therapies.

Scope of this report

Thorough examination of status and impact of several novel drugs in development

Discussion of the challenges in current and future treatment strategies

Anticancer pipeline of most companies in the field

Key reasons to read this report

* Explore the strengths and weaknesses associated with compounds in clinical development. Scientific rationale for most novel therapeutics in leukemia R&D, and the results of clinical trials to date

* Gain insight into the current challenges and commercial opportunities associated with leukemia therapy

* More than 130 high quality references

Some of the drugs included in this analysis

AG-858, Alemtuzumab, AP23573, Atra, Avastin, BAY 43-9006, CEP-701, Ceplene, Clofarabine, Cloretazine, Decitabine, FK228, Flavopiridol, Gemtuzumab, Genasense, Gvax, Imatinib, OSI-461, PKC PKC Protein Kinase C (biochemistry)
PKC Public Key Cryptography
PKC Public Key Certificate
PKC PaKua Chang (Chinese martial art)
PKC Paroxysmal Kinesigenic Choreoathetosis
412, PTK PTK Phi Theta Kappa
PTK Protein Tyrosine Kinase (insulin receptor)
PTK Polskiego Towarzystwa Kardiologicznego (Polish Cardiac Society)
PTK Phototherapeutic Keratectomy
PTK Pairwise Transient Key
787, Rituximab, SU5416, Troxacitabine, Valspodar, VELCADE, Xcytrin and Zarnestra

Content Outline:

1 Executive Summary

2 Cancer Highlights

3 Methodology

4 Table of Contents

5 Introduction

6 Current Treatment Strategies

7 Progress in Current Treatment Strategies

8 Key Therapeutic Strategies for Future Therapies

9 Competitive Landscape in Drug Development: The Late Stage Pipeline

10 Current Drug Development: The Early Stage Pipeline

13 Drug Index

14 Company Index

4.1 List of Boxes

4.2 List of Tables

Some of the companies included in this analysis:

Amgen, Antigenics, Bayer, Bioenvision, Biogen Idec, BTG BTG BIT (Built-In Test) Target Generator
BTG Bridging the Gap
BTG British Technology Group
BtG Betreuungsgesetz (Germany)
BTG Biomass Technology Group BV
BTG Begbies Traynor Group
, Cell Genesys, Cephalon Ceph´a`lon

n. 1. (Zool.) The head.
, Cyclacel Group (Cyclacel), Exelixis, Genta, GlaxoSmithKline, Johnson & Johnson, Millennium, Novartis, Pharmacyclics, PDL See page description language.

1. PDL - Page Description Language.
2. PDL - Program Design Language.
3. PDL - Push Down List.
4. PDL - Dave Lebling, one of the co-authors of Zork.
 BioPharma, Schering-Plough, SuperGen, Vion Pharmaceuticals and Wyeth

For more information visit http://www.researchandmarkets.com/reports/c43821
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

 Reader Opinion

Title:

Comment:



 

Article Details
Printer friendly Cite/link Email Feedback
Publication:Business Wire
Date:Oct 19, 2006
Words:564
Previous Article:Lipid Regulators (Statin Types Only) and Their Significance Are Monitored For Period of 2000 through To 2010 on a Global Scale.
Next Article:Learn How Higher Levels of Glycosylated Hemoglobin Increases the Risk of Death.
Topics:



Related Articles
LORUS' VIRULIZIN EFFECTIVE AGAINST PANCREATIC TUMORS.
PROGEN'S FIRST U.S. CLINICAL TRIAL WITH PI-88 BEGINS.
FDA APPROVES LORUS/NCI GTI-2040 PHASE II CLINICAL TRIAL.
Biotechnology and drug discovery: from bench to bedside.(Original Article)
Point Therapeutics Awarded $600,000 Orphan Products Development Grant to fund Company's Current Phase 2 Study of Talabostat and Rituximab in Advanced...
Callisto CEO to Detail Clinical Progress of Anti-Cancer Drug Development and other Programs at BIO 2006 Conference; CEO to Present Data on Callisto...
Callisto to Present Clinical Progress and Drug Candidate Pipeline Strategy at Equities Magazine Investor Conference; Company to Detail Ongoing and...
Callisto to Present Leading Anti-Cancer Drug Candidates at Rodman & Renshaw Healthcare Conference in Monaco; CEO Dr. Gary Jacob to Discuss Latest...
Cyclacel Begins Phase I Pharmacologic Study of Oral Sapacitabine in Patients with Advanced Leukemias.
There Are Today No Less Than 164 Emerging Therapeutics in Active Development Targeting Leukemia, From Early Preclinical To Marketed Drugs.

Terms of use | Copyright © 2009 Farlex, Inc. | Feedback | For webmasters | Submit articles