Purdue obtains United States patent.Purdue Research Foundation (W. Lafayette, IN) has patented pyridines, pharmaceutical compositions comprising such pyridines, and the use of such compositions in treating injured mammalian nerve tissue nerve tissue n. A highly differentiated tissue composed of nerve cells, nerve fibers, dendrites, and neuroglia. , including but not limited to an injured spinal cord spinal cord, the part of the nervous system occupying the hollow interior (vertebral canal) of the series of vertebrae that form the spinal column, technically known as the vertebral column. . In one embodiment, the compounds, compositions, and methods of the instant invention treat a mammalian nerve tissue injury by restoring action potential or nerve impulse nerve impulse n. A wave of physical and chemical excitation that moves along a nerve fiber in response to a stimulus. conduction through a nerve tissue lesion. Significantly, in vivo application of compounds of the instant invention established, on the basis of SSEP SSEP System(s) Safety Engineering Plan SSEP Somatosensory Evoked Potentials SSEP Short-latency Somatosensory Evoked Potential SSEP Source Selection Evaluation Plan SSEP Slim Shady EP (record by Eminem) testing, that the compounds provide longer lasting effects at lower concentrations than comparable treatment with the known agent 4-aminopyridine. (US 7,244,748) |
|
||||||||||||||||||||||
Printer friendly
Cite/link
Email
Feedback
Reader Opinion