Protein folding-misfolding; some current concepts of protein chemistry.1600214177
Protein folding-misfolding; some current concepts of protein chemistry.
Ed. by Joseph P. Zbilut and Thomas Scheibel.
Nova Science Publishers
Unlike polymers, whose molecules tend to have very large extended molecules forming a matrix, proteins tend to self-assemble and fold into compact, self-contained structures. This tendency has important implications for many areas, including sequencing and sequence-embedded information. These seven articles explain the implications of folding behavior in proteins, including the folding and self-assembly process itself and conformational switches, protein-to-protein interactions in terms of structural principle as well as the stability and kinetics kinetics: see dynamics.
Kinetics (classical mechanics)
That part of classical mechanics which deals with the relation between the motions of material bodies and the forces acting upon them. of association, understanding why and when proteins do not fold, in vitro in vitro /in vi·tro/ (in ve´tro) [L.] within a glass; observable in a test tube; in an artificial environment.
In an artificial environment outside a living organism. transcription and translation systems in protein expression and folding, protein structure prediction Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry. Its aim is the prediction of the three-dimensional structure of proteins from their amino acid sequences, sometimes including additional relevant information such as and molecular forces, recurrence recurrence /re·cur·rence/ (-ker´ens) the return of symptoms after a remission.recur´rent
1. quantification as a signal analysis approach to the study of protein sequences and structure, and the fundamentals of electrostatics electrostatics, study of phenomena associated with charged bodies at rest (see charge; electricity). A charged body has an excess of positive or negative charges, a condition usually brought about by the transfer of electrons to or from the body. .
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