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Protein 'predicts heart attack, early death, but not stroke'.

Byline: ANI

Washington, Oct 20 (ANI): Higher levels of a protein called C-reactive protein C-Reactive Protein Definition

C-reactive protein (CRP) is a protein produced by the liver and found in the blood.
Purpose

C-reactive protein is not normally found in the blood of healthy people.
 (CRP C-reactive protein (CRP)
A protein present in blood serum in various abnormal states, like inflammation.

Mentioned in: Pelvic Inflammatory Disease

CRP,
n.pr See C-reactive protein.
), a marker for inflammation in the blood, may increase a person's of heart attack and death but not stroke, says a new study.

The study, published in the October 20, 2009, print issue of Neurology, involved 2,240 people from the Northern Manhattan Study who were 40 years old or older and stroke-free. Of the group, 63 percent were Hispanic, 20 percent non-Hispanic black and 15 percent non-Hispanic white residents.

All participants had their blood tested for CRP levels and were evaluated for stroke and heart attack risk factors. They were followed for an average of eight years. In that time, there were 198 strokes, 156 heart-related events and 586 deaths.

The researchers found that people with CRP levels greater than three milligrams per liter were 70 percent more likely to suffer a heart attack and 55 percent more likely to die early compared to people who had levels of one milligram milligram /mil·li·gram/ (mg) (mil´i-gram) one thousandth (10-3) of a gram.

mil·li·gram
n. Abbr. mg
A metric unit of mass equal to one thousandth (10-3) of a gram.
 per liter or less of the protein in their blood. The protein was not associated with an increased risk of stroke once other risk factors were taken into account.

"The role of this protein in predicting risk of stroke has been controversial although prior studies have found it to be a marker for predicting risk of heart disease," said study author Mitchell Elkind, MD, MS, of Columbia University Medical Center Columbia University Medical Center is the name of the medical complex associated with Columbia University, and covers several blocks (primarily between 165th and 168th Streets from the Henry Hudson Parkway to Audubon Avenue) in the Washington Heights section of Manhattan.  in New York New York, state, United States
New York, Middle Atlantic state of the United States. It is bordered by Vermont, Massachusetts, Connecticut, and the Atlantic Ocean (E), New Jersey and Pennsylvania (S), Lakes Erie and Ontario and the Canadian province of
 and a Fellow with the American Academy of Neurology The American Academy of Neurology (AAN) is a professional society for neurologists and neuroscientists. As a medical specialty society it was established in 1949 by A.B. Baker of the University of Minnesota to advance the art and science of neurology, and thereby promote the best .

"However, in our large, multiethnic mul·ti·eth·nic  
adj.
Of, relating to, or including several ethnic groups.

Adj. 1. multiethnic - involving several ethnic groups
multi-ethnic
 population, CRP levels did not play a role in predicting stroke, though they may still help determine whether someone is at risk of heart attack or early death," the expert added.

CRP protein levels are associated with such medical and lifestyle risk factors as diabetes, smoking, alcohol consumption and physical activity.

"It appears that by living a healthy lifestyle, one may be able to lower these protein levels, thus lowering the risk of cardiac events and possibly early death," said Elkind.

"It may be that the failure of CRP to predict stroke in our study, unlike in some other populations, reflects the fact that our population is older and has more of these risk factors.

While CRP may be predictive in generally young healthy people, it may be less useful among older, sicker people. More research needs to be done on why the protein wasn't able to predict stroke in the same manner as heart disease," the expert added. (ANI)

Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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Publication:Asian News International
Date:Oct 22, 2009
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