Prolonged ulcerative laryngitis.We were visited by a 35-year-old music teacher in the public school system. She had been trained as a professional singer, but she used her voice professionally only in the classroom situation. She was a lifelong nonsmoker and nondrinker, and she had been treated in the past for gastroesophageal reflux disease gastroesophageal reflux disease (GERD) Disorder characterized by frequent passage of gastric contents from the stomach back into the esophagus. Symptoms of GERD may include heartburn, coughing, frequent clearing of the throat, and difficulty in swallowing. . She came to us after a 2-year absence from our practice with complaints of hoarseness, harsh cough, sore throat, and fever. Laryngeal examination revealed very edematous e·dem·a·tous adj. Marked by edema. , mobile vocal folds with small nodular swellings and evidence of early laryngotracheitis. Initial treatment included amoxicillin, methylprednisolone methylprednisolone /meth·yl·pred·nis·o·lone/ (-pred-nis´ah-lon) a synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant; also , voice rest, continued use of her albuterol inhaler, and Robitussin as needed for cough. When she returned 1 week later for followup, she was still hoarse, and she had a persistent cough and generalized fatigue. Strobovideolaryngoscopy revealed severe vocal fold inflammation and ulceration, especially on the right vocal fold (figure). She was then placed on a 10-day course of clarithromycin, prednisone, and complete voice rest. She was seen weekly in the office, and she ultimately received slightly more than 1 month of treatment with clarithromycin, steroids, and vocal rest. Eventually, her voice and vocal fold appearance returned to normal. This case study illustrates the nature of prolonged ulcerative ulcerative /ul·cer·a·tive/ (ul´se-ra?tiv) (ul´ser-ah-tiv) pertaining to or characterized by ulceration. ulcerative pertaining to or characterized by ulceration. laryngitis. This condition requires diligent surveillance and patience, as recovery time has been found to take from several weeks to several months from the time of the initial office visit. From the Department of Otolaryngology--Head and Neck Surgery, Graduate Hospital and Thomas Jefferson University It began as Jefferson Medical College in 1824. On July 1, 1969 the institution officially became Thomas Jefferson University. The university is made up of three colleges:
implacable detective with photographic memory. [Br. Lit.: The Ticket-of-Leave Man, Barnhart, 546] See : Sleuthing ), Philadelphia. |
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