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Progen Half-Year Report -- Good Progress.


Business Editors/Health/Medical Writers

BRISBANE, Australia--(BUSINESS WIRE)--March 6, 2003

Progen Industries Ltd (ASX ASX

See: Australian Stock Exchange
:PGL Persistent generalized lymphadenopathy (PGL)
A condition in which HIV continues to produce chronic painless swellings in the lymph nodes during the latency period.

Mentioned in: AIDS
)(Nasdaq:PGLAF PGLAF Project Gutenberg Literary Archive Foundation ) reporting its half-year results today announced progressive results from all divisions.

Strong revenue contributions are being made by Commercial Services (Contract Manufacturing and Lifesciences Sales & Distribution). Contract Manufacturing revenue was up by 332% to $927,000 and Lifesciences Sales & Distribution income increased by 13.5% to $1.4 million, compared to the previous corresponding period. Recent negotiation of several international and local contracts for Contract Services and a new Lifesciences agency distribution agreement for a new product line should enable the division to reach the $4.2 million budget and the profitability target for 2003. Total operating revenue operating revenue

Revenue from any regular source. Revenue from sales is adjusted for discounts and returns when calculating operating revenue. Compare other revenue.
 increased by 28.7%.

Research and Development expenditure increased by 19.7% as anticipated compared to the previous half-year reflecting the increased level of activities over the reporting period. New initiatives include the commencement of a fourth Phase I/II clinical trial with PI-88 in lung cancer lung cancer, cancer that originates in the tissues of the lungs. Lung cancer is the leading cause of cancer death in the United States in both men and women. Like other cancers, lung cancer occurs after repeated insults to the genetic material of the cell. , a new collaboration agreement with the Australian National University's Research School of Chemistry to complement our Drug Discovery efforts and the in-licensing of an additional potential anti-cancer treatment for liver cancer Liver Cancer Definition

Liver cancer is a relatively rare form of cancer but has a high mortality rate. Liver cancers can be classified into two types.
 code-named PI-166.

The operating loss operating loss

The excess of operating expenses over revenue. As with operating income, operating losses exclude revenues and expenses from operations that are not considered a regular part of the business. Also called deficit. Compare operating income.
 before equity accounting for the investment in Medigen Biotechnology Corp. (MBC (Multimedia Benchmark Committee) A graphics benchmark that provides MPEG-2 and other tests. See GPC. ) has been maintained at $3.33 million in comparison with $3.28 million for the corresponding period. This result has been achieved through vigilant cash management, significantly increased Commercial Services revenue and focused research and development activities.

The increase in the company's share of MBC's loss by 52.9% from $580,000 to $887,000 is indicative of the increased level of expenditure incurred by the MBC through its own; in-licensing initiatives, investment in biotech ventures and ongoing operational costs.

The operating loss from ordinary activities after tax of $4.2 million compared to $3.8 million is in line with the Company's expectations.

Progen's CFO See Chief Financial Officer.  Milton McColl commented, "The half-year report card indicates that we are on track and the company remains focused towards continuing this performance into the second half-year."


Review and Results of Operations:

                                                  2002          2001
                                                 $'000         $'000
Revenue from sales of goods                      1,399         1,232
Revenue from sales of services                     927           279
Revenue from other ordinary operating
 activities                                        705           844
                                            -----------   -----------
TOTAL REVENUE                                    3,031         2,355
                                            -----------   -----------

Profit/(Loss) before R&D and recognition of
 Medigen Biotechnology Corp.                      (503)         (917)

Research and Development                        (2,824)       (2,360)
                                            -----------   -----------

Profit/(Loss) before recognition of
 Medigen Biotechnology Corp.                    (3,327)       (3,277)

Equity accounting for loss in
 associate company                                (887)         (580)

                                            -----------   -----------
Profit/(Loss) from ordinary activities
 before tax                                     (4,214)       (3,857)

Income Tax                                         Nil           Nil

                                            -----------   -----------
Profit/(Loss) from ordinary activities
 after tax                                      (4,214)       (3,857)
                                            -----------   -----------

Net Tangible Assets                             14,399        20,738

Net Tangible Assets per share               59.0 cents    85.0 cents

Cash and Investments at Valuation
(excluding 19.9% interest in Medigen)           10,488        15,580



About Progen

Progen Industries Ltd. (www.progen.com.au) is a globally focused biotechnology company committed to the discovery, development and commercialisation of small molecule pharmaceuticals for the treatment of a variety of diseases. The company's lead drugs PI-88 and PI-166 are under development as potential treatments for different cancers. Progen's drug discovery efforts are focused on the development of potent, selective inhibitors of carbohydrate-protein interactions, which are implicated im·pli·cate  
tr.v. im·pli·cat·ed, im·pli·cat·ing, im·pli·cates
1. To involve or connect intimately or incriminatingly: evidence that implicates others in the plot.

2.
 in a range of different diseases. The company has a GMP GMP (guanosine monophosphate): see guanine.  (Good Manufacturing Practice Good Manufacturing Practice or GMP (also referred to as 'cGMP' or 'current Good Manufacturing Practice') is a term that is recognized worldwide for the control and management of manufacturing and quality control testing of foods and pharmaceutical products. ) certified facility that develops and manufactures drug candidates for early stage clinical trials for other biotechnology companies.

This press release contains forward-looking statements that are based on current management expectations. These statements may differ materially from actual future events or results due to certain risks and uncertainties, including without limitation, risks associated with drug development and manufacture, risks inherent in the extensive regulatory approval process mandated by the United States Food and Drug Administration United States Food and Drug Administration (FDA),
n.pr a unit of the Public Health Service created to protect the health of the nation against impure and unsafe foods, drugs, and cosmetics.
 and the Australian Therapeutic Goods Administration The Therapeutic Goods Administration or TGA is the regulatory body for therapeutic goods (including medicines, medical devices, gene technology, and blood products) in Australia. , delays in obtaining the necessary approvals for clinical testing, patient recruitment, delays in the conduct of clinical trials, market acceptance of PI-88, PI-166 and other drugs, future capitals needs, general economic conditions, and other risks and uncertainties detailed from time to time in the Company's filings with the Australian Stock Exchange Australian Stock Exchange (ASX)

Australia's major securities market, formed when the six state stock exchanges (Adelaide, Brisbane, Hobart, Melbourne, Perth, and Sydney stock exchanges) were merged in 1987.
 and the United States Securities and Exchange Commission. Moreover, there can be no assurance that others will not independently develop similar products or processes or design around patents owned or licensed by the Company, or that patents owned or licensed by the Company will provide meaningful protection or competitive advantages.
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Publication:Business Wire
Geographic Code:8AUST
Date:Mar 6, 2003
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