Printer Friendly
The Free Library
14,495,914 articles and books
Member login
User name  
Password 
 
Join us Forgot password?

Presently There Are More Than 100 Companies Developing More Than 190 Antibody Drugs in More Than 350 Clinical Trials.


DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c39785) has announced the addition of Antibodies in Oncology: Drug Pipeline Update 2006 to their offering.

The commercial and therapeutic success of antibodies like Rituxan, Avastin, and Erbitux will force the industry to look into the next generation of therapeutic antibodies, preparing themselves for the second wave in the lucrative field of therapeutic antibodies. Today, there are more than 100 companies developing more than 190 antibody drugs in more than 350 clinical trials targeting around 40 different cancer indications. The number of antibody targets has increased to over 70 described molecular targets in just a few years.

Investigators - Includes more than 95 principal investigators.

Drug name & Synonyms - Lists commercial, generic and code names for drugs. In all more than 300 names.

Developmental stage Contains more than 190 active antibody drugs in development or more than 350 clinical projects for cancer:

--36 projects in Phase III

--104 projects in Phase II

--69 projects in Phase I

--145 projects in Preclinical

Cancer Indications - Antibody drugs in development for over 40 cancer indications

--Breast cancer

--Colorectal cancer

--Hematological cancers

--Lung cancer

--Melanoma

--Prostate cancer

--Etc.

Targets - More than 70 different targets. Examples:

--alpha-foetoprotein

--aspartate beta-hydroxylase

--carbonic anhydrase IX

--CD19 antigen

--CD22 antigen

--CD4 antigen (p55)

--chorionic gonadotropin gonadotropin /go·nado·tro·pin/ (-tro´pin) any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. , beta polypeptide polypeptide: see peptide.  

--coagulation factor III factor III
n.
See thromboplastin.


factor III Tissue factor, see there, aka thromboplastin
 (thromboplastin thromboplastin: see blood clotting. , tissue factor)

--cytotoxic T-lymphocyte-associated protein 4

--fms-related tyrosine kinase tyrosine kinase An enzyme intimately linked to signal transduction–ST, either as a receptor-type TK, which participates in transmembrane signaling, or as an intracellular TK, participating in ST to the nucleus; ↑ or ↓ TK activity is associated with  4

--gastrin

--heat shock 90kDa protein 1, alpha

--insulin-like growth factor 1 receptor

--integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

--interleukin 6 receptor

--parathyroid hormone-like hormone

--prostate stem cell stem cell

In living organisms, an undifferentiated cell that can produce other cells that eventually make up specialized tissues and organs. There are two major types of stem cells, embryonic and adult.
 antigen

--telomerase reverse transcriptase

--t-umor necrosis factor receptor superfamily superfamily /su·per·fam·i·ly/ (soo´per-fam?i-le)
1. a taxonomic category between an order and a family.

2.
, member 8

--v-erb-b2 erythroblastic erythroblastic

of, or relating to erythroblasts.


erythroblastic islets
a bone marrow unit consisting of a central macrophage and surrounding erythroblasts and in which differentiation of erythroblasts takes place.
 leukemia viral oncogene oncogene

Gene that can cause cancer. It is a sequence of DNA that has been altered or mutated from its original form, the proto-oncogene (see mutation). Proto-oncogenes promote the specialization and division of normal cells.
 homologue homologue /ho·mo·logue/ (hom´ah-log)
1. any homologous organ or part.

2. in chemistry, one of a series of compounds distinguished by addition of a CH2 group in successive members.
 2, neuro/glioblastoma derived oncogene homologue (avian)

--Etc

Description - Progress analysis and review of drug development.

A typical drug profile reports on:

--Drug Name & Synonyms

--Investigator(s)

--Indication(s)

--Developmental Stage(s)

--Mechanism(s)

--Target(s)

--Clinical Development

--Developmental History

--Scientific Data

--Patents

--In/Out-licensing

--Collaborations

--Analysts Comments

How May Drug Pipeline Update Be of Use?

Show investors/board/management that you are right on top of drug development progress in your therapeutic area.

Find competitors, collaborations partners, M&A candidates etc.

Jump start competitive drug intelligence operations.

Excellent starting point for world wide benchmarking.

Compare portfolio and therapy focus with your peers.

Speed up pro-active in-/outlicensing strategy work.

Fast and easy way of tracking drugs using search engines; just one click and you may search World Wide Web and PubMed for any drug with all its synonyms.

Drug Pipeline Update is Delivered to You as a CD-ROM CD-ROM: see compact disc.
CD-ROM
 in full compact disc read-only memory

Type of computer storage medium that is read optically (e.g., by a laser).
 application.

Drug Pipeline Update is fitted into a CD-ROM based application, for your intelligent usage:

Smart CD-ROM application, which makes it easy to use and navigate by

Multiple search and sort functions included

Drug data is linked to search engines like Google and PubMed

Direct links to web pages from inside the application

Found information is easily shared with others over email, file export or in print

For more information visit http://www.researchandmarkets.com/reports/c39785
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

 Reader Opinion

Title:

Comment:



 

Article Details
Printer friendly Cite/link Email Feedback
Publication:Business Wire
Date:Jul 21, 2006
Words:503
Previous Article:Marchex Announces Regular Quarterly Dividend for 4.75% Convertible Exchangeable Preferred Stock.
Next Article:Qwest to Open New Solutions Center in Loveland; Customers Can Visit Qwest's Entertainment Area to Try Digital TV, Wireless, Broadband, and Digital...
Topics:



Related Articles
Therapeutic monoclonal antibody okayed.
Benefit of Betaseron confirmed.
TRANXENOGEN SIGNS MONOCLONAL ANTIBODY DEVELOPMENT PACTS.
GPC BIOTECH GETS GERMANY PERMITS FOR MONOCLONAL ANTIBODY.
Blockbuster Drugs Rituxan, Avastin, and Erbitux Changes the Way the Pharmaceutical Industry Looks upon Antibody Treatment Of Cancer.
Progenics Broadens Collaboration with Seattle Genetics for Prostate Cancer Therapy; Positive Preclinical Findings on PSMA Antibody-Drug Conjugate...
Seattle Genetics and Agensys Announce Collaboration to Co-Develop and Commercialize Antibody-Drug Conjugate Therapies for Cancer.
In-Depth Competitive Landscape Assessment of the Cancer Immunotherapy Market Place.
Seattle Genetics Highlights Data on its Proprietary Antibody-Drug Conjugate Technology at AACR.
Biothera's Imprime PGG(TM) Enhanced Effectiveness of Avastin(R) in Cancer Study.

Terms of use | Copyright © 2009 Farlex, Inc. | Feedback | For webmasters | Submit articles