Presenting a Solid Grounding in the Fundamental Principles of Lipid Absorption in the Intestines and Vascular Body Systems - Lipid Excipients in Modifying Oral and Parenteral Drug Delivery.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c47870) has announced the addition of Role of Lipid Excipients excipients, n.pl all the constituents of a remedy that lack medicinal properties. See also adjuvant, auxiliary substance, and vehicle. in Modifying Oral and Parenteral parenteral /pa·ren·ter·al/ (pah-ren´ter-al) not through the alimentary canal, but rather by injection through some other route, as subcutaneous, intramuscular, etc. par·en·ter·al adj. 1. Drug Delivery: Basic Principles and Biological Examples to their offering. The principles and formulation of lipid-based drug delivery systems With its promise for improving drug absorption, the emerging field of lipid-based drug delivery systems has attracted considerable attention from academia to industry. Filling the need for a standard text on the subject, this book assembles a group of experienced investigators and educators from the front line of pharmaceutical sciences to provide a comprehensive resource on the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. Presenting a solid grounding in the fundamental principles of lipid absorption in the intestines and vascular body systems, the text gives readers in-depth insight into the formulation issues, such as dissolution testing Dissolution testing is a critical formulation tool in the process of drug discovery that entails measuring the stability of the investigational product, achieving uniformity in production lots and determining its in vivo availability. and stability testing, and physiological and biopharmaceutical issues, including the role of specific enzymes, the evaluation of transport systems in the body, and the mechanisms governing the transport of water-insoluble drugs. Chapters cover: * Interaction of drug transporters with excipients * Formulation issues around lipid-based oral and parenteral delivery systems * Biological implications of lipid-based parenteral drug delivery systems * Principles in the development of intravenous lipid emulsions * Protein adsorption adsorption, adhesion of the molecules of liquids, gases, and dissolved substances to the surfaces of solids, as opposed to absorption, in which the molecules actually enter the absorbing medium (see adhesion and cohesion). patterns on parenteral lipid formulations--a key factor determining the in vivo in vivo /in vi·vo/ (ve´vo) [L.] within the living body. in vi·vo adj. Within a living organism. in vivo adv. fate * Nanoparticle targeting for drug delivery across the blood-brain barrier blood-brain barrier n. Abbr. BBB A physiological mechanism that alters the permeability of brain capillaries so that some substances, such as certain drugs, are prevented from entering brain tissue, while other substances are allowed to * Lipid-coated perfluorocarbon nanostructures as parenteral therapeutic agents Author information Kishor M. Wasan, PhD, is a Professor and Distinguished University Scholar at The University of British Columbia Locations Vancouver The Vancouver campus is located at Point Grey, a twenty-minute drive from downtown Vancouver. It is near several beaches and has views of the North Shore mountains. The 7. Faculty of Pharmaceutical Sciences. He is the Chairman of the AAPS AAPS American Association of Pharmaceutical Scientists AAPS Association of American Physicians and Surgeons AAPS Ann Arbor Public Schools AAPS American Association of Plastic Surgeons AAPS African Association of Political Science Focus Group in Parenteral Lipid-Based Drug Delivery Systems. His research has earned him over $10 million in grants and funding, and he has written over 290 peer-reviewed publications and abstracts. In addition, he holds five patents and has worked as a consultant and publications reviewer. Dr. Wasan is a Fellow of the American Association of Pharmaceutical Sciences (AAPS) and a member of the Canadian Society of Pharmaceutical Sciences, American Pharmacists Association The American Pharmacists Association (previously known as the American Pharmaceutical Association) is the first-established professional society of pharmacists within the United States and has over 60,000 members.[1] It was founded in 1852. (APhA), and Pharmaceutics and Drug Delivery Awards Committee, among others. Content Outline: Preface. Contributors. Chapter 1. Interaction of Drug Transporters with Excipients (K. Sandy Pang, Lichuan Liu, and Huadong Sun). Chapter 2. Formulation Issues around Lipid-Based Oral and Parenteral Delivery Systems (Seong Hoon hoon Austral & NZ slang Noun a loutish youth who drives irresponsibly Verb to drive irresponsibly Jeong, Jae Hyung Park and Kinam Park). Chapter 3. Lipid-Based Parenteral Drug Delivery Systems: Biological Implications (Vladimir P. Torchilin). Chapter 4. Principles in the Development of Intravenous Lipid Emulsions (Joanna Rossi and Jean-Christophe Leroux). Chapter 5. Protein adsorption patterns on parenteral lipid formulations-key factor determining the in vivo fate (Rainer H. Muller and Torsten M. Goppert). Chapter 6. Nanoparticle targeting for drug delivery across the blood brain barrier (James Egbert, Werner Geldenhuys, Fancy Thomas, Paul R. Lockman, Russell J. Mumper and David D. Allen). Chapter 7. Lipid-Coated Perfluorocarbon Nanostructures as Parenteral Therapeutic Agents (Evan C. Unger, Terry O. Matsunaga and Reena Zutshi). Index For more information visit http://www.researchandmarkets.com/reports/c47870. |
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