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Power3 Medical Files Patent Application for 47 Neurodegenerative Biomarkers.


Direct and Indirect Cost of Treating Alzheimer's in U.S. at $100 Billion Annually

HOUSTON -- Power3 Medical Products Inc. (OTC OTC

See: Over-the-counter.


OTC

See over-the-counter market (OTC).
: PWRM PWRM Pre-Positioned War Reserve Materiel , www.Power3Medical.com), today announced the filing of another patent application - its seventh in the last 10 months -- for 47 new biomarkers it has discovered and validated for use in the early diagnosis and detection of neurodegenerative diseases neurodegenerative diseases

diseases characterized by neurodegeneration. Lesions are microscopic only but in chronic disease with massive involvement there may be grossly visible atrophy of affected nervous tissue.
, including Alzheimer's, Parkinson's and ALS Als (äls), Ger. Alsen, island, 121 sq mi (313 sq km), Sønderjylland co., S Denmark, in the Lille Bælt, separated from the mainland by the narrow Alensund. .

Power3 has 15 patents pending with the U.S. Patent and Trademark Office, including a filing earlier this week for 10 new biomarkers for early detection and treatment of breast cancer. That patent application is in addition to an earlier utility filing in December 2006 for 12 other protein biomarkers in blood serum Blood serum
A component of blood.

Mentioned in: Bites and Stings


blood serum

the residual fluid of blood after clotting has occurred. It is plasma after the fibrinogen has been removed.
.

"Alzheimer's disease Alzheimer's disease (ăls`hī'mərz, ôls–), degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia.  (AD) is of particular interest because of the soaring number of cases and spiraling costs for caring for the 4.5 million Americans believed to have AD," said Steven Rash, chairman and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Power3. "Industry experts say that the direct and indirect cost of caring for AD patients in the U.S. alone is some $100 billion annually (Frost & Sullivan, www.frost.com). We believe that treatments that delay the onset and progression of AD by five years could save $50 billion in health care spending annually."

18 Million with Alzheimer's, 34 Million by 2025

Mr. Rash said that even though there is no definitive test for Alzheimer's "other than an autopsy," medical industry statistics show some 18 million people worldwide have AD - with the total projected to nearly double to 34 million by 2025.

"There are no proven treatments to delay the onset or prevent the progression of Alzheimer's," he said. "Power3 believes that the ability to rapidly and accurately distinguish Alzheimer's from other forms of dementia and neurological neurological, neurologic

pertaining to or emanating from the nervous system or from neurology.


neurological assessment
evaluation of the health status of a patient with a nervous system disorder or dysfunction.
 and vascular disorders with similar symptoms, prognoses, and treatments is one of the most critical issues in medicine today.

Power3 believes that use of protein biomarkers in blood can accelerate diagnosis and delivery of treatment and help pharmaceutical companies screen patients for clinical trials. Mr. Rash said. The blood serum concentrations of the 47 protein biomarkers covered in the patent filing, he said, have been determined in samples from more than 600 neurodegenerative disease Neurodegenerative disease
A disease in which the nervous system progressively and irreversibly deteriorates.

Mentioned in: Amnesia
 patients and normal control individuals.

"When Power3 identifies a biomarker biomarker /bio·mark·er/ (bi´o-mahr?ker)
1. a biological molecule used as a marker for a substance or process of interest.

2. tumor marker.


bi·o·mark·er
n.
1.
, we fully characterize it so as to determine the precise molecules to test for," said Dr. Ira Goldknopf, the company's director of proteomics.

Power3 a Proteomics Pioneer

Mr. Rash said Power3's approach is based on its pioneering efforts in proteomics, and "critical to the value of our intellectual property and essential for developing high-throughput commercial diagnostic tests, in addition to monitoring the progress of patients during treatment or clinical trials and in discovering drug targets.

"Because early signs of Alzheimer's are so difficult to distinguish from normal signs of aging, most patients are not diagnosed until neuronal neu·ro·nal
adj.
Relating to a neuron.



neuronal

pertaining to or emanating from a neuron.


neuronal abiotrophy
see hereditary neuronal abiotrophy of Swedish Lapland dogs.
 damage is extensive," Mr. Rash said. "The ready availability of diagnostic biomarkers in the blood would enable physicians to diagnose more AD patients earlier and begin treatments when they could be most effective. The failure of potential drugs to clear clinical trials is also a key factor driving research into biomining for new unique biomarkers to predict response and monitor treatment."

"Power3," he said, "has made substantial progress on several fronts - all biomarker-based - and seeks to license its proprietary technologies to pharmaceutical companies and manufacturers of diagnostic tests for the development of commercial applications. We are pro-actively involved with strategic partners in the U.S. and abroad, in diagnostic and pharmaceutical arenas, to facilitate the accelerated introduction of our technology into the marketplace."

About Power3 Medical Products

Power3 Medical Products, Inc. (OTC: PWRM, www.Power3Medical.com), is a leading proteomics company engaged in the commercialization of protein biomarkers, pathways, and mechanisms of diseases, through the development of diagnostic tests and drug targets for cancer and neurodegenerative diseases. Power3's patent-pending technologies are being used to develop screening and diagnostic tests for the early detection and treatment of disease, and its identified protein biomarkers, drug targets, and diagnostic tests are targeted toward markets with critical unmet un·met  
adj.
Not satisfied or fulfilled: unmet demands. 
 needs in areas such as breast cancer and neurodegenerative disease. Power3 operates a state-of-the-art proteomics laboratory in The Woodlands (Houston), Texas.

This press release contains forward-looking statements forward-looking statement

A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections.
 within the meaning of section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. With the exception of historical information contained herein, the matters discussed in this press release involve risk and uncertainties. Actual results could differ materially from those expressed in any forward-looking statement.
COPYRIGHT 2007 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Feb 22, 2007
Words:755
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