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Pluristem Closes on $13.5 Million Private Equity Investment.


NEW YORK -- Pluristem Life Systems, Inc. (OTCBB OTCBB

See OTC Bulletin Board (OTCBB).
:PLRS PLRS Position Location Reporting System
PLRS Passive Laser Restraint System (Knight Rider/KITT) 
)(DAX:PJT PJT Partners for Just Trade (St. Louis, MO)
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), a bio-therapeutics Company dedicated to the commercialization of products for a variety of malignant, degenerative and auto-immune indications, announced today it has closed on a private equity investment in the Company totaling approximately $13.5 million. The financing, which is a continuation of the investment announced on February 14, 2007, included as investors the Technion-Israel Institute of Technology and inventors who collaborated on the technology and whose patents were acquired by Pluristem.

Mr. Zami Aberman, CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Pluristem Life Systems stated: "The response to this capital raise was extraordinary and provides us with the financing we need to complete the development of our first product, PLX-I, and explore the use of our placental expanded mesenchymal stem (PLX PLX Pharmacy, Laboratory, and Radiology (X-Ray)
PLX Power Line Exchange
) cells for other clinical indications. Our current capital position enables us to develop our business and take advantage of emerging opportunities. I am delighted that these new investors and the inventors of our basic technology have shown such great confidence in Pluristem."

Pluristem is developing PLX-I as a safe and effective alternative to bone marrow transplantation Bone Marrow Transplantation Definition

The bone marrow—the sponge-like tissue found in the center of certain bones—contains stem cells that are the precursors of white blood cells, red blood cells, and platelets.
. PLX-I is an allogeneic allogeneic /al·lo·ge·ne·ic/ (-je-ne´ik)
1. having cell types that are antigenically distinct.

2. in transplantation biology, denoting individuals (or tissues) that are of the same species but antigenically
 product, based on supplementing hematopoietic stem cells (HSCs) contained in umbilical cord blood umbilical cord blood Transplantation A source of primitive and stem cells that can be used to reconstitute BM destroyed by aplastic anemia or by RT or chemotherapy for CA, lymphoproliferative malignancies. See Bone marrow transplantation, Stem cell therapy.  (CB) to improve the effectiveness of HSCs engraftment engraftment /en·graft·ment/ (en-graft´ment) incorporation of grafted tissue into the body of the host.
Engraftment
The process of transplanted stem cells reproducing new cells.
 and shorten recovery times. PLX-I mesenchymal stem cells were proven to increase the engraftment of HSCs from CB by up to five fold in a pre-clinical study.

About Pluristem

Pluristem Life Systems, Inc. is a Company dedicated to the commercialization of non-personalized (allogeneic) stem cell therapy stem cell therapy Cell therapy Molecular medicine A technology in which a person's own cells–eg, neuronal stem cells are triggered to revert to their primitive embryonic form, then redifferentiate into mature cells of various organs  products for the treatment of numerous severe degenerative, malignant and autoimmune disorders. The Company's first planned product, PLX-I, targets a $2 billion market and is intended to resolve the global shortfall of matched tissue for bone marrow transplantation (BMT BMT bone marrow transplantation.
BMT,
n.pr See bone marrow transplant.

BMT Bone marrow transplant, see there
) by improving the engraftment of hematopoietic stem cells (HSCs) contained in umbilical cord blood (CB).

Pluristem's products are derived from mesenchymal stem cells (MSCs) obtained from the placenta and expanded in the Company's proprietary PluriX(TM) 3D bioreactor bioreactor

a container in which living organisms carry out a biological reaction.
 that imitates the natural microstructure of bone marrow and does not require supplemental growth factors, cytokines or other exogenous materials. Pluristem believes the resultant expanded cells, termed PLX cells, are multipotent and able to differentiate into a variety of cell types as well as being immune-privileged to protect the recipient from immunological reactions that often accompanies transplantation. Pluristem believes their future products will participate in the approximate $30 billion therapeutic and regenerative cellular market.

Pluristem has offices and is incorporated in the USA with research and manufacturing facilities in Israel.

www.pluristem.com

Safe Harbor Statement

This press release contains statements, which may constitute "forward-looking statements" regarding our intent, belief or current expectations. Forward-looking statements in this release include that closing of this financing provides us with the financing we need to complete the development of our first product, PLX-I and explore the use of our placental expanded mesenchymal stem (PLX) cells for other clinical indications; that our current capital position enables us to develop our business and take advantage of emerging opportunities. Factors that could prevent our forward looking statements from being achieved include that we may be unable to get regulatory approval for our products; we may be unsuccessful in developing any products; our technology may not be validated as we progress further and our methods may not be accepted by the scientific community; we may be unable to retain or attract key employees whose knowledge is essential to the development of our products; unforeseen scientific difficulties may develop with our process; results in the laboratory may not translate to equally good results in real surgical settings; our patents may not be sufficient to protect essential aspects of our technology; competitors may invent better technology; our products may not work as well as hoped or worse, our products may harm recipients; and we may not be able to raise funds for development or working capital when we require it. As well, our products may never develop into useful products and even if they do, they may not be approved for sale to the public. For further risk factors see the Company's latest 10-KSB filed with the SEC.
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Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:May 22, 2007
Words:690
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