Phytoestrogens have a modest positive impact on bone tissue and on the development of osteoporosis in experimental animals. (Executives: FYI).

Phytoestrogens have a modest positive impact on bone tissue and on the development of osteoporosis in experimental animals. However, well-designed human studies are needed before making general recommendations. European researchers have established a database on phytoestrogens within European diets. The database includes almost 300 foods commonly consumed in Europe. Included are isoflavones (genistein and daidzein), coumestrol, formononetin, biochanin A and lignans. Based on this database and the dietary intake in several countries, phytoestrogen intake in Europe is estimated to be less than 1 mg/day, compared to an intake of up to 100 mg/day in Asia. Bioavailability studies confirmed that most phytoestrogens are readily absorbed by humans, but this varies somewhat, possibly due to a variability in gut microflora, diet and metabolism. Contact: Francesco Branca, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione (INRAN), Via Ardeatina, 546, 00178 Rome, Italy. Phone: [phone]. Fax: [phone]. Email:[e-mail].