Pharmaco-Behavioral Therapy in Treatment of Premature Ejaculation.

Pharmaco-Behavioral Therapy in Treatment of Premature Ejaculation, Amr I. El-Meliegy and Hussein H. Ghanem, Amr El-Meliegy, Saudi Arabia

We compared the post-treatment maintenance effect of pharmacotherapy with paroxetene hydrochloride and the combination of pharmaco-behavioral therapy. The study included 170 potent men, age 23-57 years (mean = 34) complaining of premature ejaculation with intra-vaginal ejaculation latency of less than 3 minutes. Group A (n = 85) was treated with oral paroxetine hydrochloride 20 mg/day for 3 months. Group B (n = 85) was given the same dose for the same period together with behavioral therapy (start-stop/squeeze techniques). The two groups were tracked at the end of the treatment and one month after discontinuing treatment. In group A, 81% of patients were satisfied with the results versus 85% in group B. After one month, 37% of patients in group A reported maintenance of therapeutic effects vs. 73% in group B. The immediate results of pharmacotherapy and pharmacobehavioral therapy were comparable; however, the maintenance of the therapeutic effect was significantly better with pharmaco-behavioral therapy.