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PerkinElmer Launches 19 New Products at Society for Biomolecular Screening 'SBS' Conference.


ORLANDO, Florida -- New products focus on live cell screening, ADME/Tox, and Emerging Therapeutic Targets

PerkinElmer, Inc. (NYSE NYSE

See: New York Stock Exchange
: PKI (Public Key Infrastructure) A framework for creating a secure method for exchanging information based on public key cryptography. The foundation of a PKI is the certificate authority (CA), which issues digital certificates that authenticate the identity of ), a leading provider of drug discovery, life science research and analytical solutions, today announced that it will be exhibiting 19 new products at the Society for Biomolecular Screening (SBS See Small Business Server. ) 10th Annual Conference and Exhibition in Orlando, Florida, September 11-15, Booth 600.

"As a leader in the drug discovery marketplace, PerkinElmer is committed to helping our customers solve their most pressing problems. During this year's SBS, we are launching a host of products aimed at enhancing our customers' transition to cellular screening, mitigating the ADME/Tox bottleneck, and driving fundamental productivity improvements into the drug discovery and development process," said John Danner, vice president and general manager of PerkinElmer's biopharmaceutical business.

PerkinElmer's new products fall into three categories: Live cell screening and ADME/Tox, Reagent platforms and proprietary consumables, and Automation and detection. The showcased products include:

Live cell screening and ADME/Tox:

--CellLux(TM) uHTS Cellular Screening System: featuring patented fiber-optic imaging with integrated liquid handling for high-throughput live cell "inject and read" applications. The CellLux is ideal for ion channel ion channel
n.
See channel.
 screening, an increasingly important drug discovery application.

--CellEx(TM) Poly-D-lysine coated microplates: proprietary new technology to anchor live cells onto a microplate for robust cellular applications ... a perfect fit with the new CellLux.

--Cellular Workstation: fully integrated and automated workstation for conducting live cell screening, tying together PerkinElmer's detection, liquid handling, and chemistry technologies and creating a walk-away, easy-to-use solution for a variety of cellular applications.

--ATP-Lite(TM) One-step: a high-throughput live cell assay for evaluating compounds' toxic effects on cells. This easy-to-use, scalable approach allows customers to perform toxicity testing during primary screening, thus enabling the elimination of poor candidate compounds much earlier in the drug discovery process.

Reagent platforms and proprietary consumables:

--LANCE(TM) cAMP: a sensitive, robust, 1536-well capable cAMP assay, based upon PerkinElmer's proven LANCE(TM) TRF TRF

thyrotropin releasing factor.
 technology ... optimized for a wide range of PerkinElmer detection platforms.

--Easy-Lite(TM) Kinase: an antibody-free luminescence luminescence, general term applied to all forms of cool light, i.e., light emitted by sources other than a hot, incandescent body, such as a black body radiator.  detection method addressing all kinase targets, saving customers precious time and money spent on sourcing and screening antibodies.

--LANCE Beta-Secretase: an optimized assay kit enabling customers to screen a key target related to Alzheimer's disease in a robust, high-throughput, cost-effective manner.

--New AlphaScreen(TM) protocols: highly sensitive, homogeneous uHTS assays for the increasingly important applications of Ubiquitin u·biq·ui·tin
n.
A polypeptide found in all eukaryotic cells, including plant cells, that participates in a variety of cellular functions including protein degradation.
 and Guanylate Cyclase screening.

--OptiPlate(TM) 384-HS: microplate specifically designed to reduce background interference for uHTS imaging assays... a perfect complement to the ViewLux uHTS imager.

--Image-Mix cocktail: proprietary, red-shifted liquid scintillation scintillation /scin·til·la·tion/ (sin?ti-la´shun)
1. an emission of sparks.

2. a subjective visual sensation, as of seeing sparks.

3.
 cocktail that enables customers to significantly increase throughput of laborious, slow radiometric assays.

--Four New GPCR GPCR Guanine Nucleotide-Binding Protein-Coupled Receptor
GPCR GTP-binding Protein-Coupled Receptor
 Receptor and Ligands: key new offerings include Gastric Inhibitory Polypeptide gastric inhibitory polypeptide
n. Abbr. GIP
A peptide hormone secreted by the stomach that stimulates insulin release as part of the digestive process.


gastric inhibitory polypeptide GIP, see there
 (GIP GIP - 1. General Interpretive Programme.

A 1956 interpreted language for the English Electric DEUCE, with array operations and an extensive library of numerical methods.
) and GPR (Ground Penetrating Radar) A UWB-based technology that locates objects buried underground. It is used to locate buried lines, storage tanks, pipes and conduits as well as to determine the structural integrity of the ground underneath a road or runway. 8, thus continuing PerkinElmer's commitment to enabling novel GPCR target research.

Automation and detection:

--EnVision(TM) "Turbo" AlphaScreen capability: new technology enhancements double the power of current EnVision AlphaScreen detection, thus increasing throughput and sensitivity, as well as expanding applications.

--FlexDrop(TM) EX: new precision reagent dispenser for rapid dispensing of solvents, reagents, buffers and cells ... enables dispensing of 1-4 reagents in volumes from 200 nL to 2.0 mL, with dispense accuracy of less than or equal to 5%. The new EX model includes two stacker cassettes with capacity for up to 50 SBS-standard microplates for automated, walk-away processing.

--ViewLux(TM) uHTS software enhancements: significantly increases screening flexibility, expands data analysis capability, and improves fluorescence performance.

--ELISA Workstation: a fully integrated, walk-away workstation, automating traditionally labor-intensive, multi-step ELISA ELISA (e-li´sah) Enzyme-Linked Immuno-Sorbent Assay; any enzyme immunoassay using an enzyme-labeled immunoreactant and an immunosorbent.

ELISA
n.
 assays. The ELISA workstation utilizes application-specific protocols integrated with PerkinElmer detectors, washers, and dispensers, thus speeding up the process from sample preparation to results generation.

Along with highlighting its array of products at this year's conference, PerkinElmer will also present its 8th annual PerkinElmer Award for Innovation in HTS HTS Heights
HTS Harmonized Tariff System
HTS High Throughput Screening (biomolecular assay screening)
HTS High-Throughput Screening (Pharmaceutical Industry)
HTS Harmonized Tariff Schedule
. This year's award will be presented to Dr. Steven A. Hofstadler of Ibis ibis (ī`bĭs), common name for wading birds with long, slender, decurved bills, found in the warmer regions of both hemispheres. The body is usually about 2 ft (61 cm) long. Most ibises nest in colonies.  Therapeutics for his work in mass spectrometry focusing on characterizing microorganisms and noncovalent complexes between RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
 and small drug-like molecules.

Factors Affecting Future Performance

This press release contains "forward-looking" statements within the meaning of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Any statements contained in this press release that relate to prospective events or developments, including, without limitation, statements regarding our estimate for 2003 results of operations, are deemed to be forward-looking statements. Words such as "believes," "anticipates," "plans," "expects," "projects," "forecasts," "will" and similar expressions are intended to identify forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by these forward-looking statements, including risks related to our debt levels, our ability to comply with the financial covenants contained in our credit agreements, a further downturn in our customers' markets, our failure to introduce new products in a timely manner, regulatory changes, risks related to our international operations, our inability to integrate acquired businesses into our existing business and to successfully combine our Life and Analytical Sciences businesses and competition, as well as other factors which we describe under the caption "Forward-Looking Information and Factors Affecting Future Performance" in our most recently filed annual report on Form 10-K and in our most recently filed quarterly report on Form 10-Q. We disclaim any intention or obligation to update any forward-looking statements as a result of developments occurring after the date of this press release.

PerkinElmer, Inc. is a global technology leader focused in the following businesses - Life and Analytical Sciences, Optoelectronics and Fluid Sciences. Combining operational excellence and technology expertise with an intimate understanding of our customers' needs, PerkinElmer provides products and services in health sciences and other advanced technology markets that require innovation, precision and reliability. The Company serves customers in more than 125 countries, and is a component of the S&P 500 Index. Additional information is available through www.perkinelmer.com or 1-877-PKI-NYSE.
COPYRIGHT 2004 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2004, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Sep 10, 2004
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