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PerkinElmer Introduces Two Comprehensive Multiplexing Platforms for Genomic Research at ASHG.


PerkinElmer continues to broaden its genomic research profile, offering comprehensive multiplexing platforms that improve the pace and precision of research

NEW ORLEANS New Orleans (ôr`lēənz –lənz, ôrlēnz`), city (2006 pop. 187,525), coextensive with Orleans parish, SE La., between the Mississippi River and Lake Pontchartrain, 107 mi (172 km) by water from the river mouth; founded  -- PerkinElmer, Inc. (NYSE NYSE

See: New York Stock Exchange
: PKI (Public Key Infrastructure) A framework for creating a secure method for exchanging information based on public key cryptography. The foundation of a PKI is the certificate authority (CA), which issues digital certificates that authenticate the identity of ), a global leader in Health Sciences and Photonics, today announced that it will unveil its new multiplexing technologies for genomic research at the 2006 American Society of Human Genetics Human genetics

A discipline concerned with genetically determined resemblances and differences among human beings. Technological advances in the visualization of human chromosomes have shown that abnormalities of chromosome number or structure are surprisingly
 (ASHG ASHG American Society of Human Genetics ) Annual Meeting, being held October 9-13, in New Orleans, Louisiana. The Comprehensive Solution (CS)[TM] Autoplex Gene Expression Platform and the Spectral Genomics Spectral Genomics, Inc. is a technology technology spin-off company from Baylor College of Medicine, selling aCGH microarrays and related software. History
The company was founded in February 2000 by BCM technologies.
 Array Comparative Genomic Hybridization Array comparative genomic hybridization (also CMA, Chromosomal Microarray Analyisis, Microarray-based comparative genomic hybridization, array CGH, a-CGH, or aCGH  (CGH CGH Comparative Genomic Hybridization
CGH Changi General Hospital (Singapore)
CGH Computer-Generated Hologram
CGH Community General Hospital (Syracuse, NY) 
) Platform provide important tools for improving gene expression validation, molecular karyotyping Karyotyping
A laboratory test used to study an individual's chromosome make-up. Chromosomes are separated from cells, stained, and arranged in order from largest to smallest so that their number and structure can be studied under a microscope.
 and genome profiling.

"With the acquisition of Spectral Genomics and our partnership with Luminex([R]) Corporation to use xMAP([R]) technology, PerkinElmer is strengthening its commitment to the genomics market," said Robert F. Friel, president of PerkinElmer Life and Analytical Sciences. "We now offer solutions that accelerate the discovery and validation of genomic profiles and applications."

Within the CS Autoplex Platform, PerkinElmer is launching two products for gene expression validation -- a custom gene expression panel kit and a labeling kit, both with analysis software. The CS Autoplex Custom Gene Expression Panel Kit enables researchers to customize their candidate gene panels for the high throughput validation of large sample sets. Validation of genomic biomarkers is a critical area of research for drug discovery and potential disease diagnostics. These kits, built upon Luminex's xMAP[R] technology, are designed to reduce the cost of sample processing, while facilitating the progress of microarray-based discovery by efficiently validating biomarkers with reproducible results. CS Autoplex Analysis Software offers a familiar output format for standard ratiometric microarray data analysis and visualization.

The Company will also show the PerkinElmer CS Autoplex Workstation, which completes the CS Platform by offering the latest in automated multiplex technology for assay set-up, sample processing and analysis for high content xMAP([R]) technology.

With the Spectral Genomics Array CGH Platform, PerkinElmer is now the only company to offer a Bacterial Artificial Chromosome A bacterial artificial chromosome (BAC) is a DNA construct, based on a fertility plasmid (or F-plasmid), used for transforming and cloning in bacteria, usually E. coli.  (BAC BAC
abbr.
blood alcohol concentration
) based integrated solution consisting of the SpectralChip 2600 array, the Constitutional Chip 3.0 array, the ScanArray[TM] System, labeling reagents and SpectralWare[TM] Analysis Software which reduces research time. Researchers can use the platform for discovery and investigational purposes. This PerkinElmer solution can generate results in 24 hours versus the industry standard of five to 20 days in the lab, which is common for standard karyotyping.

For discovery, the SpectralChip 2600 array is the first technology to be released under the PerkinElmer name since the Company's acquisition of Spectral Genomics in April 2006. The SpectralChip 2600 array is the only complete BAC array platform for genome profiling that offers greater throughput, resolution and ease of use in a single technology.

As part of PerkinElmer's genetic screening portfolio, the Constitutional Chip 3.0 array is being introduced for investigational use in cytogenetics cytogenetics /cy·to·ge·net·ics/ (-je-net´iks) the branch of genetics devoted to cellular constituents concerned in heredity, i.e. chromosomes. . The Constitutional Chip 3.0 BAC CGH microarray, being evaluated for coverage of 42 disorders and 41 subtelomeric regions, offers an attractive alternative to current Fluorescence In Situ Hybridization Fluorescence in situ hybridization (FISH)
A technique for diagnosing DiGeorge syndrome before birth by analyzing cells obtained by amniocentesis with DNA probes. FISH is about 95% accurate.
 (FISH) technology. This entry into the post-natal cytogenetics testing market will further expand PerkinElmer's robust portfolio of newborn and child health diagnostics and risk assessment tools.

For those attending the ASHG conference, PerkinElmer will host a luncheon on Wednesday, October 11, 2006, featuring speaker Warren G. Sanger, Ph.D., FACMG, Director, Human Genetics Laboratory and Professor, Pediatrics and Pathology/Microbiology at the Munroe-Meyer Institute and speaker Michael Sheldon, Ph.D., Assistant Professor, Department of Pediatrics and Biostatistician, Baylor Microarray Core Facility at Baylor College of Medicine Baylor College of Medicine is a private medical school located in Houston, Texas, USA on the grounds of the Texas Medical Center. It has been consistently rated the top medical school in Texas and among the best in the United States. .

More information about these innovative technologies can be found at www.perkinelmer.com.

Factors Affecting Future Performance

This press release contains "forward-looking" statements within the meaning of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995, including, but not limited to, statements relating to estimates and projections of future earnings per share and revenue growth and other financial results, developments relating to our customers and end-markets, and plans concerning business development opportunities. Words such as "believes," "intends," "anticipates," "plans," "expects," "projects," "forecasts," "will" and similar expressions, and references to guidance, are intended to identify forward-looking statements. Such statements are based on management's current assumptions and expectations and no assurances can be given that our assumptions or expectations will prove to be correct. A number of important risk factors could cause actual results to differ materially from the results described, implied or projected in any forward-looking statements. These factors include, without limitation: (1) our failure to introduce new products in a timely manner; (2) our ability to execute acquisitions and license technologies, or to successfully integrate acquired businesses and licensed technologies into our existing business or to make them profitable; (3) our failure to protect adequately our intellectual property; (4) the loss of any of our licenses or licensed rights; (5) our ability to compete effectively; (6) fluctuation in our quarterly operating results and our ability to adjust our operations to address unexpected changes; (7) our ability to produce an adequate quantity of products to meet our customers' demands; (8) our failure to maintain compliance with applicable government regulations; (9) regulatory changes; (10) economic, political and other risks associated with foreign operations; (11) our ability to retain key personnel; (12) restrictions in our credit agreement; (13) our ability to realize the full value of our intangible assets; and (14) other factors which we describe under the caption "Risk Factors" in our most recent annual report on Form 10-K Form 10-K

A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information.


Form 10-K

See 10-K.
 and in our most recent quarterly report on Form 10-Q Form 10-Q

See 10-Q.
 and in our other filings with the Securities and Exchange Commission. We disclaim any intention or obligation to update any forward-looking statements as a result of developments occurring after the date of this press release.

Other Information

Health Sciences end markets include genetic screening, environmental, service, biopharma, and medical imaging. Photonics markets include sensors and specialty lighting.

PerkinElmer, Inc. is a global technology leader driving growth and innovation in Health Sciences and Photonics markets to improve the quality of life. The Company reported revenues of $1.5 billion in 2005, has 8,000 employees serving customers in more than 125 countries, and is a component of the S&P 500 Index. Additional information is available through www.perkinelmer.com or 1-877-PKI-NYSE.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Oct 9, 2006
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