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PE Biosystems and Sequenom Sign Agreement to Provide Mass Spectrometry Products for MassArray Analysis.


FRAMINGHAM, Mass. & SAN DIEGO--(BW HealthWire)--Aug. 18, 1999--

The PerSeptive Biosystems Division of PE Biosystems (NYSE NYSE

See: New York Stock Exchange
: PEB PEB Physical Evaluation Board
PEB Presidential Emergency Board
PEB Post Exposure Bake
PEB Professional Engineers Board (Singapore)
PEB Pre-Engineered Building
PEB Personal Electronic Ballot
PEB Performance Evaluation Board
), a PE Corporation business, and Sequenom Inc. announced today that they have entered into a supply agreement to provide mass spectrometry mass spectrometry
 or mass spectroscopy

Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields.
 products for Sequenom's MassArray(TM) technology and its SpectroCHIP(TM) miniaturized array format.

"We are pleased that PerSeptive Biosystems, a world leader in MALDI-TOF MALDI-TOF Matrix Assisted Laser Desorption Ionization - Time of Flight  mass spectrometer production offers technology that supports Sequenom's SpectroCHIP array format," said Hubert Koster, Ph.D., Sequenom's president and chief executive officer. "The addition of this key supplier relationship further validates the acceptance of Sequenom's MassArray format as we move into our commercial phase. Our customers will be able to benefit from the quality biomolecular analysis of PerSeptive Biosystems' mass spectrometer united with the accuracy and high throughput of Sequenom's MassArray technology."

PerSeptive's Voyager-DE(TM) mass spectrometer will become a key component of Sequenom's MassArray system that also integrates SpectroCHIP arrays, proprietary solid phase enzymatic reactions and customized software, enabling the analysis of biomolecules This page aims to list articles on Wikipedia that describe particular biomolecules or types of biomolecules.

This list is not necessarily complete or up to date - if you see an article that should be here but isn't (or one that shouldn't be here but is), please update the page
 with 100 percent accuracy and at industrial-scale high throughput. The Company's MassArray Analytical System is designed for use in large-scale pharmacogenomics and life science research and product development programs. Sequenom's products allow the validation and scoring of genetic markers and the stratification of patient populations for clinical studies with the speed, accuracy and cost-effectiveness required of an industrial process.

According to Joe Malandrakis, vice president and general manager of PerSeptive Biosystems, "This agreement allows Sequenom to supply their customers with the Voyager-DE Biospectrometry Workstations to obtain the accurate results required for successful mass analysis. We are looking forward to contributing to Sequenom's MassArray technology and to build upon this relationship between the two companies."

The use of MALDI MALDI Matrix-Assisted Laser Desorption/Ionization  TOF (Top Of Form) The beginning of a physical paper form. To position paper in many printers, the printer is turned offline, the forms are aligned properly and the TOF button is pressed.  has a fundamental impact on the analytical process, because it detects biomolecules directly and therefore labels and separation steps are not needed. MALDI-TOF MS directly measures molecules during time-of-flight according to the difference in molecular weights, combining separation, detection and characterization in one single step. Characterization of a molecule is obtained because the weight of a molecule is a physical standard and allows unambiguous identification. This combined process of separation, detection and characterization takes place in less than milliseconds because the molecular ions are flying through the high vacuum without resistance, and, with Sequenom's bioinformatics software, the signals are immediately recorded as electronic signals in the computer, ready for further data mining and archiving.

PE Corporation currently comprises two operating groups: PE Biosystems Group and Celera Genomics Group. PE Biosystems, with sales of $1.2 billion during fiscal 1999, develops and markets instrument-based systems, reagents, software and contract-related services to the life science industry and research community. PE Biosystems Group comprises four divisions: Applied Biosystems, PerSeptive Biosystems, PE Informatics, and Tropix. Celera Genomics, a newly formed business unit, intends to become the definitive source of genomic and related medical information. Information about the Company is available on the World Wide Web at http://www.pe-corp.com or by phoning 800/762-6923.

Sequenom develops high definition genetic analysis tools, custom applications and proprietary information based on mass spectrometry. By the end of this year, Sequenom will commercially launch its MassArray Basic System, a modular, semi-automated platform, including the SpectroSCAN(TM) array mass spectrometer, SpectroJET(TM) nanoplotter and bioinformatics workstation. Also offered will be the MassArray Industrial System including an Automated Process Line (APL (A Programming Language) A high-level mathematical programming language noted for its brevity and matrix generation capabilities. Developed by Kenneth Iverson in the mid-1960s, it runs on micros to mainframes and is often used to develop mathematical models. ), offering additional robotics and software to fully automate the DNA analysis DNA analysis Any technique used to analyze genes and DNA. See Chromosome walking, DNA fingerprinting, Footprinting, In situ hybridization, Jeffries' probe, Jumping libraries, PCR, RFLP analysis, Southern blot hybridization.  process thereby meeting the high throughput demands in an industrial setting. The Company will also sell the proprietary consumables, including SpectroCHIPs(TM), reagents and application specific software and will license access to population-based DNA banks to verify drug targets and marker identification and validation databases.

Sequenom's intellectual property consists of 23 issued or allowed U.S. patents and over 90 pending patent applications. The Company is headquartered in San Diego, California “San Diego” redirects here. For other uses, see San Diego (disambiguation).
San Diego is a coastal Southern California city located in the southwestern corner of the continental United States. As of 2006, the city has a population of 1,256,951.
 with offices in Hamburg, Germany and Boston, Massachusetts.

Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as "believe," "expect," "intend," "anticipate," "should," "planned," "estimated," and "potential," among others. These forward-looking statements are based on PE Corporation's current expectations. The Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995 provides a "safe harbor Safe Harbor

1. A legal provision to reduce or eliminate liability as long as good faith is demonstrated.

2. A form of shark repellent implemented by a target company acquiring a business that is so poorly regulated that the target itself is less attractive.
" for such forward-looking statements. In order to comply with the terms of the safe harbor, PE Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. The risks and uncertainties that may affect the operations, performance, development, and results of PE Biosystems businesses include but are not limited to (1) dependence on new products; (2) sales dependent on customers' capital spending capital spending

Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years.
 policies and government-sponsored research; (3) claims for patent infringement patent infringement n. the manufacture and/or use of an invention or improvement for which someone else owns a patent issued by the government, without obtaining permission of the owner of the patent by contract, license or waiver. ; (4) significant overseas operations; (5) future growth strategy; (6) uncertainty of success of Year 2000 compliance plan; (7) earthquakes; and (8) other factors that might be described from time to time in PE Corporation's filings with the Securities and Exchange Commission.

The names Sequenom, DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 MassArray, SpectroCHIP and Industrial Genomics are trademarks of Sequenom, Inc. The names PerSeptive and Voyager-DE are trademarks of PE Biosystems, Inc. "PerSeptive Biosystems is a registered trademark, and PE, PE Biosystems and Voyager DE are trademarks of PE Corporation or its subsidiaries."
COPYRIGHT 1999 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1999, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Aug 18, 1999
Words:878
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