Optimata's Virtual Patient Technology to Support Development of Eli Lilly Drug Candidate.RAMAT GAN Ramat Gan (rä`mät gän), city (1994 pop. 122,200), W central Israel, adjacent to Tel Aviv. Founded in 1921, Ramat Gan is an important industrial center. Food processing is the chief industry; construction materials are also made there. , Israel -- Optimata Ltd. today announced the completion of the first phase of a pilot collaboration project with Eli Lilly Eli Lilly can refer to:
adj. Of, relating to, or producing a toxic effect on cells. cy  to·tox·ic compound. In the course of the collaboration Optimata's researchers will use Optimata's proprietary virtual cancer patient software to evaluate pre-clinical data provided by Eli Lilly. Working hand-in-hand with Eli Lilly's staff, Optimata will suggest ways of optimizing the clinical drug development program through in-silico prediction of the expected response in humans. "We are excited to have this opportunity to work with a leading pharmaceutical manufacturer like Eli Lilly," said Guy Malchi, President of Optimata. Optimata's virtual patient technology is based on a computer-generated method of accurately predicting how individual patients or patient populations will respond to a compound. The technology combines computer models of human physiology Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. , specific diseases and the therapeutic impact of a compound. The technology forecasts the results of putative Alleged; supposed; reputed. A putative father is the individual who is alleged to be the father of an illegitimate child. A putative marriage is one that has been contracted in Good Faith and pursuant to ignorance, by one or both parties, that certain preclinical preclinical /pre·clin·i·cal/ (-klin´i-k'l) before a disease becomes clinically recognizable. pre·clin·i·cal adj. 1. and clinical experiments at an unprecedented scale, allowing an unlimited number of "virtual trials" to be carried out on a wide range of dosages, treatment schedules and patient population characteristics. The collaboration will draw upon Optimata's biomathematical and disease modeling expertise which enables an accurate portrayal of the dynamics of disease processes and detailed predictions of drug effects. The collaboration will demonstrate how using Optimata's Virtual Patient technology can aid in shortening clinical development time and provide guidance for focused clinical trials. About Optimata Optimata Ltd. is a science-based, interdisciplinary company, dedicated to the development of predictive biosimulation technologies -- Virtual Patient Engines. Optimata offers a rational approach for the selection of patient populations and the optimization of drug scheduling and dosage. Optimata's technology is based on a computer-generated method of accurately predicting how individual patients or patient populations will respond to a compound. The technology combines computer models of human physiology, specific diseases and the therapeutic impact of a compound. The in-silico technology enables drug developers to conduct experiments at an unprecedented scale, enabling an unlimited number of "virtual trials" to be carried out on an almost infinite combination of dosages, treatment schedules and patient population characteristics. The company is currently completing a bio-simulation clinical trial on individualized in·di·vid·u·al·ize tr.v. in·di·vid·u·al·ized, in·di·vid·u·al·iz·ing, in·di·vid·u·al·iz·es 1. To give individuality to. 2. To consider or treat individually; particularize. 3. breast cancer therapy in collaboration with Nottingham City Hospital Nottingham City Hospital is a large hospital located in Nottingham, UK. With Queen's Medical Centre, it forms the Nottingham University Hospitals NHS Trust. The City Hospital is the oldest of Nottingham's two hospitals, founded in 1903. in the UK and Soroka University Medical Center in Israel. For more information about Optimata visit www.optimata.com. |
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