On omeprazole and iron replacement.I read with great interest the article (1) entitled "Effect of Omeprazole on Oral Iron Replacement in Patients With Iron Deficiency Anemia Iron Deficiency Anemia Definition Anemia can be caused by iron deficiency, folate deficiency, vitamin B12 deficiency, and other causes. The term iron deficiency anemia means anemia that is due to iron deficiency. ." The authors declared that the patients presented here are the first of their kind to be reported to be spoken of; to be mentioned, whether favorably or unfavorably. See also: Report . However, this relation has been well known for a long time and is expressed in classical textbooks such as Rudolph's Pediatrics (2) and Hematology of Infancy and Childhood. (3) Fortunately, the use of proton pump inhibitors Proton Pump Inhibitors Definition The proton pump inhibitors are a group of drugs that reduce the secretion of gastric (stomach) acid. They act by binding with the enzyme H+, K(+)-ATPase, hydrogen/potassium adenosine triphosphatase is seldom necessary in pediatric patients, since peptic ulcer disease Peptic ulcer disease (PUD) A stomach disorder marked by corrosion of the stomach lining due to the acid in the digestive juices. Mentioned in: Indigestion peptic ulcer disease See Duodenal ulcer, Gastric ulcer, GERD. is rare in children. Therefore, treatment with these drugs (and their attendant complications) is relatively uncommon in children. Widespread use of these drugs in adults should probably cause more complications than seen in children. References 1. Sharma VR, Brannon MA, Carloss EA. Effect of omeprazole on oral iron replacement in patients with iron deficiency anemia. South Med J 2004; 97:887-889. 2. Bridges KR, Pearson HA. Nutritional anemias: iron deficiency iron deficiency A relative or absolute deficiency of iron which may be due to chelation in the GI tract, loss due to acute or chronic hemorrhage or dietary insufficiency Sources Meat, poultry, eggs, vegetables, cereals, especially if fortified with iron; per the , in Rudolph CD, Rudolph AM (eds): Rudolph's Pediatrics. New York New York, state, United States New York, Middle Atlantic state of the United States. It is bordered by Vermont, Massachusetts, Connecticut, and the Atlantic Ocean (E), New Jersey and Pennsylvania (S), Lakes Erie and Ontario and the Canadian province of , McGraw-Hill, 21st edition, 2002, pp 1525-1528. 3. Andrews NC. Disorders of iron metabolism and sideroblastic anemia: iron deficiency, in Nathan DG, Orkin SH, Ginsburg D, Look AT (eds): Nathan and Oski's Hematology of Infancy and Childhood. Philadelphia, Saunders, 6th edition, 2003, pp 470-471. Musa Kazim Caglar, MD Gaziosmanpasa University Faculty of Medicine Department of Pediatrics Tokat, Turkey Letters to the Editor are welcomed. They may report new clinical or laboratory observations and new developments in medical care or may contain comments on recent contents of the Journal. They will be published, if found suitable, as space permits. Like other material submitted for publication, letters must be typewritten type·write intr. & tr.v. type·wrote , type·writ·ten , type·writ·ing, type·writes To engage in writing or to write (matter) with a typewriter. , double-spaced, and submitted in duplicate. They must not exceed two typewritten pages in length. No more than five references and one figure or table may be used. See "Information for Authors" for format of references, tables, and figures. Editing, possible abridgment, and acceptance remain the prerogative of the Editors. |
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