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Oddities of circadian rhythms.

* Heart attacks are twice as likely to happen between 8:00 and 10:00 a.m., than at 4:00 a.m. and 6:00 a.m. and between 6:00 and 8:00 p.m.

* In one particular study, eating one meal a day of 2,000 calories resulted in a weight loss when eaten at breakfast, but produced a weight gain as supper.

* Women go into labor most often between 1:30 and 2:30 a.m. and least frequently about midday. Births between 2:00 and 4:00 p.m. are associated with increased probability of complications in both baby and mother.

* People are more allergic around 11:00 p.m. while antihistamine drugs have the greatest impact in the morning.

* The senses of hearing, taste and smell are more acute at certain times of the day. Studies show sensory acuity is highest at 3:00 a.m., then falls of rapidly to a low at 6:00 a.m. then rises to another peak between 5:00 and 7:00 p.m. (This cycle is related to the hormone cycle: when steroid hormones are released, sensory acuity fails).

* The length of time a person sleeps is related more closely to body temperature rhythms and bedtime than to how long the person has been awake. In experiments, even after being awake more than 20 hours, people free of time cues slept twice as long when they went to bed when their temperature was at its highest (in early evening) than when it was at its lowest (in the early morning).

* Implantable computerized drug pumps, currently under investigation, will make it possible to vary dosage of medications according to the time of day as well as other factors. These devices will infuse drugs and can be programmed to deliver various dosages at different times.
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Title Annotation:The Tyranny of Time: Solving the Mystery of Our Inner Clockwork; includes related articles
Publication:Nutrition Health Review
Date:Jan 1, 1992
Words:306
Previous Article:Living in perpetual twilight.
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