Novel Strategy for Growing Functional Heart Tissue is Described in Tissue Engineering.NEW ROCHELLE, N.Y. -- By ensuring a good blood supply and enclosing young cardiac cells in protective silicone tubes scientists have engineered a three-dimensional model for growing functional heart tissue that could be used to replace the heart muscle damaged in patients suffering from congestive heart failure congestive heart failure, inability of the heart to expel sufficient blood to keep pace with the metabolic demands of the body. In the healthy individual the heart can tolerate large increases of workload for a considerable length of time. , as reported in the May/June issue (Volume 11, Number 5-6) issue of Tissue Engineering, a peer-reviewed journal peer-reviewed journal Refereed journal Academia A professional journal that only publishes articles subjected to a rigorous peer validity review process. Cf Throwaway journal. published by Mary Ann Liebert, Inc. The paper is available free online at www.liebertpub.com/ten. This study demonstrates the potential for successful surgical transplantation and survival of therapeutic, tissue-engineered models comprised of cardiac cells that obtain the blood and nourishment they need to be able to multiply and organize into functional heart muscle. Ravi Birla, Ph.D., Gregory Borschel, M.D., Robert Dennis, Ph.D., and David Brown, M.D., from the University of Michigan (body, education) University of Michigan - A large cosmopolitan university in the Midwest USA. Over 50000 students are enrolled at the University of Michigan's three campuses. The students come from 50 states and over 100 foreign countries. , Ann Arbor, and Harvard-MIT HST (1) See Hubble Space Telescope. (2) An earlier asymmetrical modem protocol from U.S. Robotics that included error control and compression and transmits from 4800 to 14400 bps in one direction and from 300 to 400 bps in the other. , Cambridge, MA, placed cardiac muscle cardiac muscle n. The muscle of the heart, consisting of anastomosing transversely striated muscle fibers formed of cells united at intercalated disks; the myocardium. Also called muscle of heart. cells taken from newborn rats into silicone chambers, which they surgically introduced into adult rats, placing them in close proximity to the femoral artery and vein, which provided the necessary blood supply to ensure growth of the cells, enabling them to fill the chambers with living, beating heart tissue within three weeks. "This study provides evidence of the degree to which cardiac tissue can now be engineered successfully - an important step on the path toward vital support for human hearts in the clinic," says Peter C. Johnson, M.D., President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Scintellix, LLC (Logical Link Control) See "LANs" under data link protocol. LLC - Logical Link Control and Co-Editor in Chief of Tissue Engineering. Tissue Engineering is an authoritative peer-reviewed journal published bimonthly bi·month·ly adj. 1. Happening every two months. 2. Happening twice a month; semimonthly. adv. 1. Once every two months. 2. Twice a month; semimonthly. n. pl. in print and online that brings together scientific and medical experts in the fields of biomedical engineering, material science, molecular and cellular biology, and genetic engineering. Tissue Engineering is the official journal of the Tissue Engineering Society international, European Tissue Engineering Society and the Asian Tissue Engineering Society. Tables of contents and a free sample issue may be viewed online at www.liebertpub.com/ten. Mary Ann Liebert, Inc., is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Human Gene Therapy, Stem Cells and Development, and Cloning and Stem Cells. Its biotechnology trade magazine, Genetic Engineering News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 60 journals, books, and newsmagazines is available at www.liebertpub.com. |
|
||||||||||||||
Printer friendly
Cite/link
Email
Feedback
Reader Opinion