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Nonoxynol-9 dangers: health experts warn against rectal use.


On September 27 over 80 health experts and organizations released a letter warning against all rectal use of nonoxynol-9 non·ox·y·nol-9 (nn-ks-nôl (N-9)--a spermicide
spermi·cidal (-sdl) adj.
 mistakenly used to kill HIV, when actually it makes transmission worse. The letter came after a quiet campaign that persuaded most but not all manufacturers to remove the substance from their products. Experts agree that rectal use is dangerous and never appropriate--and that N-9 should not be included in any condoms or lubricant.

On October 10 the Bay Area Reporter, a San Francisco gay newspaper, reported that all lubricant manufacturers had now promised to stop making lubricant with N-9. This followed an earlier series of articles in the B.A.R. that prompted some local retailers to remove N-9 products from their shelves.

From the September 27 consensus letter:

Call to Discontinue Nonoxynol-9 for Rectal Use

We, the undersigned, in light of recent statements by the World Health Organization and the Centers for Disease Control, urge all people to cease the rectal use of products containing Nonoxynol-9 (N-9). We are concerned that many people mistakenly believe that N-9 provides extra protection against HIV and STDs when used rectally when in fact there is reason to think that rectal use of N-9 may increase risk of infection.

The Centers for Disease Control states: "N-9 can damage the cells lining the rectum
rec·tums or rec·ta (-t) 
The terminal portion of the large intestine, extending from the sigmoid flexure to the anal canal.
, thus providing a portal of entry for HIV and other sexually transmissible transmissible /trans·mis·si·ble/ (trans-mis´i-b'l) capable of being transmitted.

trans·mis·si·ble (trns-ms
 agents. Therefore, N-9 should not be used as a microbicide
1. a substance that destroys microbes.
2. a substance that destroys infectious agents, including also viruses; sometimes used specifically for that used to prevent transmission of sexually transmitted diseases.microbici´dal


mi·cro·bi·cide (m
 or lubricant during anal sex."

The World Health Organization World Health Organization (WHO), specialized agency of the United Nations, established in 1948, with its headquarters at Geneva. WHO admits all sovereign states (including those not belonging to the United Nations) to full membership, and it admits territories that are not self-governing to associate membership. There are 192 member nations. states: "N-9 should not be used rectally." (Further) "There is no published scientific evidence that N-9-lubricated condoms provide any additional protection against pregnancy or STIs compared with condoms lubricated with other products.

"Since adverse effects due to the addition of N-9 to condoms cannot be excluded, such condoms should no longer be promoted."

For More Information

* On September 25 The Wall Street Journal published "Some Makers, Venders Drop N-9 Spermicide on HIV Risk.

* The World Health Organization consensus report is at: http://www.who.int/reproductive-health/rtis/nonoxynol9.html

* And on September 28, 2002, The Lancet formally published results of a major study in Africa that showed that N-9 could increase HIV transmission--available at http://www.thelancet.com (free registration required).
COPYRIGHT 2002 John S. James
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2002, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Author:James, John S.
Publication:AIDS Treatment News
Date:Oct 18, 2002
Words:374
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