Nonlinear Dynamics Plans to Enter Biomarker Discovery Market with New Software Analysis Solution.NEWCASTLE-UPON-TYNE, England -- Nonlinear Dynamics nonlinear dynamics, study of systems governed by equations in which a small change in one variable can induce a large systematic change; the discipline is more popularly known as chaos (see chaos theory). Ltd, a leading provider of bioinformatics solutions, today announced it has undertaken a large scale development program to evolve a new biomarker discovery Biomarker discovery is the process by which biomarkers are discovered. It is a medical term. Many commonly used blood tests in medicine are biomarkers. The way that these tests have been found can be seen as biomarker discovery. product range. The new development program will see the launch of multiple biomarker products to form a robust and scalable solution for the analysis of mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. and capillary electrophoresis Capillary electrophoresis (CE), also known as capillary zone electrophoresis (CZE), can be used to separate ionic species by their charge and frictional forces. In traditional electrophoresis, electrically charged analytes move in a conductive liquid medium under the trace data. This will incorporate a range of new powerful analytical tools for biomarker discovery, predictive modelling Predictive modelling is the process by which a model is created or chosen to try to best predict the probability of an outcome. In many cases the model is chosen on the basis of detection theory to try to guess the probability of a signal given a set amount of input data, for and data processing. John Spreadbury, Group Sales Group sales Block sale (of large amounts) of securities to institutional investors. group sales The distribution of a new security issue to institutional clients. and Marketing Director of Nonlinear Dynamics, and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Nonlinear USA Inc, commented: "The fields of drug discovery, biomedical research and pharmacogenomics are developing around the use of biomarkers in accordance with new FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. guidelines. The result is that many pharma and biotech companies have reconfigured their research models to incorporate biomarker functionality. However at present, widespread implementation of this technique is hampered by the lack of accurate, hardware independent software commercially available to researchers. "In developing a new biomarker range, Nonlinear is applying its considerable experience and expertise in mining and analysing data from multiple applications. Our outstanding technical portfolio underlines the adaptability of our development processes to construct an innovative and targeted research platform specifically aimed at biomarker discovery." The first release from this development program will be a medium throughput analysis tool aimed at the academic market. Set for launch in Q3 2005, Phoretix Biomarker represents a highly usable and flexible software solution for entry level trace data analysis and visualisation. This will incorporate a range of adaptable analysis features to import, analyse and identify individual and multiple markers from trace samples. This is achieved through an automated m/z picking algorithm to distinguish particular peaks of interest, while eliminating sample 'noise'. Spectra can be visualised using a variety of different graphical formats, including stacking and spectral overlay, as well as simulated gel maps. Comparative visual analysis across multiple samples enables rapid discovery of disparate features for later identification. Phoretix Biomarker further extends these capabilities with powerful neighbour joining and UPGMA UPGMA Unweighted Pair Group Method, Arithmetic Mean hierarchical clustering algorithms. Philippe Bogard, Strategic Marketing Manager of Nonlinear Dynamics, added: "Single protein biomarkers with clinically relevant predictive power are very rare and often lack the sensitivity and specificity required for effective research. By applying multiple data-handling and visualisation options, users can identify and review data from multiple markers with increased confidence. Marker data can then be queried, validated and classified via a range of database options. This represents a considerable improvement over single marker statistics, and a breakthrough for any lab conducting biomarker discovery." About Nonlinear Dynamics Ltd Established in 1989, Nonlinear Dynamics is a leading worldwide provider of bioinformatics solutions to the life science industry. The Company's innovative product portfolio comprises high-quality analysis and data mining tools for 1D and 2D electrophoresis gels and microarrays, the core technologies of genomics and proteomics. Nonlinear sells and supports its products through its UK headquarters, its USA office, and its global network of partners and OEM (Original Equipment Manufacturer) The rebranding of equipment and selling it. The term initially referred to the company that made the products (the "original" manufacturer), but eventually became widely used to refer to the organization that buys the products and resellers. |
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