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Next Pharmaceuticals Launches New Natural Product That Boosts Good Cholesterol and Lowers Bad Cholesterol.


Clinical Trial Shows Flavoxine[TM] Addresses Multiple Risk Factors of Heart Health

CARLSBAD, Calif. -- Next Pharmaceuticals today announced the results of a clinical trial on their new-patented heart health ingredient Flavoxine[TM]. The double-blind placebo-controlled clinical trial with 80 subjects showed that Flavoxine[TM] significantly increased HDL-cholesterol, the so-called "good" cholesterol while significantly reducing LDL-cholesterol, the so-called "bad" cholesterol, and triglycerides Triglycerides
Fatty compounds synthesized from carbohydrates during the process of digestion and stored in the body's adipose (fat) tissues. High levels of triglycerides in the blood are associated with insulin resistance.
. In addition, Flavoxine[TM] significantly reduced C-reactive protein C-Reactive Protein Definition

C-reactive protein (CRP) is a protein produced by the liver and found in the blood.
Purpose

C-reactive protein is not normally found in the blood of healthy people.
 (CRP C-reactive protein (CRP)
A protein present in blood serum in various abnormal states, like inflammation.

Mentioned in: Pelvic Inflammatory Disease

CRP,
n.pr See C-reactive protein.
), an indicator of inflammation that is now considered to be another positive risk factor for coronary artery disease coronary artery disease, condition that results when the coronary arteries are narrowed or occluded, most commonly by atherosclerotic deposits of fibrous and fatty tissue. , and it significantly lowered blood pressure and fasting blood glucose blood glucose Diabetology The principal sugar produced by the body from food–especially carbohydrates, but also from proteins and fats; glucose is the body's major source of energy, is transported to cells via the circulation and used by cells in the presence  in the overweight individuals with elevated cholesterol levels.

"Flavoxine[TM] is the result of Next Pharmaceuticals devoting many years to finding a natural formula for heart health that would have considerably greater benefits than the nutrients currently sold in dietary supplements or functional foods and beverages," said Bob Garrison, President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Next Pharmaceuticals. "We believe Flavoxine[TM] will be a blockbuster natural ingredient for maintaining a healthy heart. The active compounds from the plants used have been studied extensively and therefore Flavoxine[TM] does not have the risks frequently associated with new synthetic compounds."

Flavoxine[TM] is a blend of two plant extracts, a proprietary extract of Phellodendron amurense and a patented (U.S. Patent No. 6,987,125) extract of orange peel containing polymethoxylated flavones. The principal investigator Noun 1. principal investigator - the scientist in charge of an experiment or research project
PI

scientist - a person with advanced knowledge of one or more sciences
 for the trial was Dr. Julius E. Oben, Head of the Department of Biochemistry, University of Yaounde in Cameroon. The increase in HDL-cholesterol in the overweight group compared to the placebo group was significant at P<0.001. The decrease in LDL-cholesterol between these two groups was significant at P<0.01. The complete results will be submitted for publication early in 2007.

Next Pharmaceuticals is seeking to replicate the trial in the U.S., through a joint effort with an academic institution under a National Institutes of Health grant.

About Next Pharmaceuticals

Next Pharmaceuticals (NP) was founded in 1997 with the purpose of developing new, patented, natural ingredients for healthy living products in the dietary supplement, food and beverage F&B is a common abbreviation in the United States and Commonwealth countries, including Hong Kong. F&B is typically the widely accepted abbreviation for "Food and Beverage," which is the sector/industry that specializes in the conceptualization, the making of, and delivery of foods.  industries. The goal of the company is to expand self-care and keep individuals out of the traditional health care system for a longer period of time. NP has successfully developed six patented plant extracts that have significantly expanded the choices for self-care products, while providing large consumer brands with powerful product differentiation Product Differentiation

A source of competitive advantage that depends on producing some item that is regarded to have unique and valuable characteristics.
. Through the application of pharmaceutical technologies to natural botanical materials, including citrus fruits, NP has developed Relora[R] for relaxation and stress-related appetite control, Nexrutine[R] for inflammation, Seditol[R] for better quality of sleep, Flavoxine[TM] & Citri-Z[R] for heart health, Citrofen[TM] for pain, and Chromulin[TM] for carbohydrate and lipid metabolism. These ingredients are available for licensing to qualified companies.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Dec 5, 2006
Words:464
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