New hope for treating diabetes and AIDS; Discovery of new human steroid conjugates offers therapeutic promise.MINNEAPOLIS--(BW HealthWire)--June 12, 1997--AMUR Pharmaceuticals Inc. today announced the discovery of a new class of human steroid conjugates. Six new steroid conjugates have been identified, the first of which is DHEA-PC (Dehydroepiandosterone-phosphocoline). Company researchers have synthesized DHEA-PC and have confirmed its biological activity. AMUR scientists have proposed that DHEA DHEA dehydroepiandrosterone. DHEA abbr. dehydroepiandrosterone DHEA, n dehydroepiandrosterone, a hormone precursor, exists naturally in yams. and DHEA-S DHEA-S Dehydroepiandrosterone Sulfate function as precursors for DHEA-PC. If correct, the discovery of DHEA-PC may represent a long-awaited breakthrough for DHEA-based therapeutics. Lead by AMUR's CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. and Chief Scientist, Dr. Fred Chasalow, the announcement was made at the 79th Annual Meeting of the Endocrine Society in Minneapolis June 11-15, 1997. The company intends to file an Investigational New Drug Application for the indications of Type II Diabetes Type II diabetes Type II diabetes is the most common form of diabetes and usually appears in middle aged adults. It is often associated with obesity and may be delayed or controlled with diet and exercise. Mentioned in: Diabetic Ketoacidosis and wasting diseases related to cancer, AIDS and aging. Discovered in 1934, the steroid hormone Dehydroepiandosterone (DHEA) and its sulfated form (DHEA-S) are made mainly in the adrenal gland and are among the most abundant hormones present in human serum. Numerous studies have revealed that DHEA and DHEA-S are precursors for transformation into androgens and/or estrogens Estrogens Hormones produced by the ovaries, the female sex glands. Mentioned in: Acne, Polycystic Ovary Syndrome estrogens (es´trōjenz), n. . AMUR Pharmaceuticals Inc. is a stage two development bio-pharmaceutical company. The company is privately held. Further information about AMUR Pharmaceuticals Inc. may be obtained via AMUR's website located on the World Wide Web @ AMUR.COM (1) (Computer Output Microfilm) Creating microfilm or microfiche from the computer. A COM machine receives print-image output from the computer either online or via tape or disk and creates a film image of each page. , or by contacting James Nikas, director of corporate development, at 415/596-1580. The information contained herein is meant purely for informational purposes. CONTACT: AMUR Pharmaceuticals Inc. Dr. Fred I. Chasalow or James Nikas, 415/596-1580 |
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