New Treatment Options Featured in NCCN Antiemesis Clinical Practice Guidelines.Business Editors/Health/Medical Writers JENKINTOWN, Pa.--(BUSINESS WIRE)--Oct. 13, 2003 The National Comprehensive Cancer Network, an alliance of nineteen of the world's leading cancer centers, announces an update of the NCCN NCCN National Comprehensive Cancer Network NCCN North Carolina Center for Nursing (Raleigh, NC) NCCN Nevada County Community Network Antiemesis Clinical Practice Guidelines clinical practice guidelines Clinical policies, practice guidelines, practice parameters, practice policies Medtalk Systematically developed statements to assist practitioner and Pt decisions about appropriate health care for specific clinical circumstances. See Psychology. . The NCCN's panel of oncology experts has added aprepitant (Emend e·mend tr.v. e·mend·ed, e·mend·ing, e·mends To improve by critical editing: emend a faulty text. (R); Merck & Co., Inc., Whitehouse Station, NJ), the first of a new class of drugs known as NK1 receptor antagonists Neurokinin NK1 antagonists are a novel class of medications that possesses unique antidepressant[1], anxiolytic[2], and antiemetic properties. The NK2 and NK3 receptors are also targets for novel classes of medications, and also show prominent antidepressive , to its recommended multidrug regimens designed to prevent nausea and vomiting Nausea and Vomiting Definition Nausea is the sensation of being about to vomit. Vomiting, or emesis, is the expelling of undigested food through the mouth. in patients undergoing highly and moderately emetogenic chemotherapy regimens Chemotherapy regimens are often identified with acronyms, identifying the agents used in combination. Unfortunately, the letters used are not consistent across regimens, and in some cases (for example, "BEACOPP") the same letter is used to represent two different treatments. . Aprepitant, which is given on day one and then at a reduced dose on days two and three of chemotherapy, is recommended by the panel to prevent both acute and delayed vomiting associated with highly emetogenic regimens, to prevent acute vomiting, and as an option for preventing delayed vomiting associated with moderately emetogenic regimens. "NCCN Clinical Practice Guidelines in Oncology are widely recognized as the standard for clinical policy in oncology. Additionally, they are being used increasingly by managed care companies to help establish coverage policy," said William T. McGivney, PhD, Chief Executive Officer of NCCN. "As such, the NCCN recognizes its responsibility to provide up-to-date information to inform decision-making. Thus, the NCCN Guidelines process is an ongoing, continual process." NCCN Clinical Practice Guidelines in Oncology are available free of charge on CD-ROM CD-ROM: see compact disc. CD-ROM in full compact disc read-only memory Type of computer storage medium that is read optically (e.g., by a laser). . These can be ordered from NCCN by calling 215-690-0300. The most up-to-date versions of the guidelines can be found at www.nccn.org. The National Comprehensive Cancer Network (NCCN), an alliance of 19 of the world's leading cancer centers, is an authoritative source of information to help patients and health professionals make informed decisions about cancer care. Through the collective expertise of its member institutions, the NCCN develops, updates, and disseminates a complete library of clinical practice guidelines. These guidelines are the standard for clinical policy in oncology. NCCN's complete spectrum of programs emphasizes improving the quality, effectiveness, and efficiency of oncology practice. |
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