New Textbook on Glial Neurobiology Provides a Thorough and Up-To-Date Overview of Glial Cells Function, the Role of Glial Cells in Various Neural Processes and Their Involvement in Nervous System Pathology.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c57315) has announced the addition of Glial glial /gli·al/ (gli´'l) of or pertaining to the neuroglia. glial of or pertaining to glia or neuroglia. glial limitans a dense network of glial processes at the pia mater. Neurobiology Neurobiology Study of the development and function of the nervous system, with emphasis on how nerve cells generate and control behavior. The major goal of neurobiology is to explain at the molecular level how nerve cells differentiate and develop their to their offering. Glial Neurobiology is the first comprehensive, accessible textbook of glial neurobiology. Authored by leading experts in the field, it provides a concise, thorough and up-do-date overview of glial cells function, the role of glial cells in various neural processes and their involvement in nervous system pathology. The book presents all major types of glial pathology; topics include: the morphology and interrelationships between glial cells and neurones in different parts of the nervous system; intra and inter cellular signaling in glial networks; the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system; cellular and molecular mechanisms of metabolic neuronal-glial interactions; and the role of glia in nervous system pathology. * Profoundly illustrated with figures, including unique images from the authors' own libraries of images, describing the main features of glial cells * Includes numerous in text boxes to highlight and summarize key facts * An associated Website includes the artwork programme from the textbook, as a set of power point slides and additional resources, including; live data (e.g. calcium signalling) and annual updates Content Outline: Preface. Part I. Physiology of Glia. Chapter 1. Introduction to Glia. 1.1 Founders of glial research: from Gabriel Valentin to Karl-Ludwig Schleich. 1.2 Beginning of the modern era. 1.3 Changing concepts: Glia express molecules of excitation. 1.4 Glia and neurones in dialogue. Chapter 2. General Overview of Signalling in the Nervous System. 2.1 Intercellular intercellular /in·ter·cel·lu·lar/ (-sel´u-lar) between or among cells. in·ter·cel·lu·lar adj. Located among or between cells. signalling: Wiring and volume modes of transmission. 2.2 Intracellular signalling. Chapter 3. Morphology of Glial Cells. 3.1 Astrocytes astrocytes (as´trōsī´ts), n a large, star-shaped cell found in certain tissues of the nervous system. A mass of astrocytes is called astroglia. See also astrocytoma. . 3.2 Oligodendrocytes. 3.3 NG2 expressing glia. 3.4 Schwann cells. 3.5 Microglia microglia /mi·crog·lia/ (mi-krog´le-ah) small nonneural cells forming part of the supporting structure of the central nervous system. They are migratory and act as phagocytes to waste products of nerve tissue. . Chapter 4. Glial Development. 4.1 Phylogeny of glia and evolutionary specificity of glial cells in human brain. 4.2 Macroglial cells. 4.3 Astroglial cells are brain stem cells. 4.4 Schwann cell lineage. 4.5 Microglial cell lineage. Chapter 5. General Physiology of Glial Cells. 5.1 Membrane potential and ion distribution. 5.2 Ion channels. 5.3 Receptors to neurotransmitters and neuromodulators. 5.4 Glial syncytium syncytium /syn·cy·ti·um/ (sin-sish´e-um) a multinucleate mass of protoplasm produced by the merging of cells. syn·cy·ti·um n. pl. - gap junctions. 5.5 Glial calcium signalling. 5.6 Neurotransmitter release from astroglial cells. 5.7 Glial neurotransmitter transporters. 5.8 Glial cells produce and release neuropeptides neuropeptides (ner·ō·pepˑ·tīdz), n.pl endogenous protein molecules that influence neural activity by carrying information directly to the cells and tissues. . 5.9 Glial cell derived growth factors. Chapter 6. Neuronal-Glial Interactions. 6.1 Close apposition apposition /ap·po·si·tion/ (ap?o-zish´un) juxtaposition; the placing of things in proximity; specifically, the deposition of successive layers upon those already present, as in cell walls. of neurones and astroglia: the tripartite synapse. 6.2 Neuronal-glial synapses. 6.3 Signalling from neurones to astrocytes 6.4 Signalling from astrocytes to neurones. 6.5 Signalling between oligodendrocytes and neurones. 6.6 Signalling between Schwann cells and peripheral nerves and nerve endings. Part II. Glial Cells and Function of Nervous System. Chapter 7. Astrocytes. 7.1 Developmental function - producing new neural cells. 7.2 Developmental function - neuronal guidance. 7.3 Regulation of synaptogenesis and control of synaptic maintenance and elimination. 7.4 Structural function - creation of the functional microarchitecture of the brain. 7.5 Structural function - creation of glial-vascular interface. (blood-brain barrier) and glia-neurone-vascular units. 7.6 Regulation of brain microcirculation microcirculation /mi·cro·cir·cu·la·tion/ (-sir?ku-la´shun) the flow of blood through the fine vessels (arterioles, capillaries, and venules).microcirculato´ry mi·cro·cir·cu·la·tion n. . 7.7 Ion homeostasis homeostasis Any self-regulating process by which a biological or mechanical system maintains stability while adjusting to changing conditions. Systems in dynamic equilibrium reach a balance in which internal change continuously compensates for external change in a feedback in the extracellular space. 7.8 Regulation of extracellular glutamate concentration. 7.9 Water homeostasis and regulation of the extracellular space volume. 7.10 Neuronal metabolic support. 7.11 Astroglia regulate synaptic transmission. 7.12 Integration in neuronal-glial networks. 7.13 Astrocytes as cellular substrate of memory and consciousness? Chapter 8. Oligodendrocytes, Schwann Cells and Myelination myelination /my·elin·a·tion/ (mi?e-lin-a´shun) myelinization. my·e·li·na·tion or my·e·li·ni·za·tion n. The acquisition, development, or formation of a myelin sheath around a nerve fiber. . 8.1 The myelin sheath. 8.2 Myelination. 8.3 Myelin myelin /my·elin/ (mi´e-lin) the lipid-rich substance of the cell membrane of Schwann cells that coils to form the myelin sheath surrounding the axon of myelinated nerve fibers. and propagation of the action potential. Part III. Glia and Pathology of Nervous System. Chapter 9. General Pathophysiology of Glia. 9.1 Reactive astrogliosis. 9.2 Wallerian degeneration. 9.3 Activation of microglia. Chapter 10. Glia and Diseases of the Nervous System. 10.1 Alexander's disease. 10.2 Spreading depression. 10.3 Stroke and ischaemia Noun 1. ischaemia - local anemia in a given body part sometimes resulting from vasoconstriction or thrombosis or embolism ischemia ischaemic stroke, ischemic stroke - the most common kind of stroke; caused by an interruption in the flow of blood to the brain . 10.4 Cytotoxic brain oedema oedema see edema. . 10.5 Neurodegenerative diseases. 10.6 Neuropathic pain. 10.7 Demyelinating diseases. 10.8 Infectious diseases. 10.9 Peripheral neuropathies 10.10 Psychiatric diseases. 10.11 Gliomas. Conclusions. Recommended literature. Index. For more information visit http://www.researchandmarkets.com/reports/c57315 |
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