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New Survey Results Show That Few Young Women Smokers Able to Quit; Nymox Pharmaceutical Corporation's NicAlert Product Offers a New Tool for Smoking Cessation Programs.


Business Editors/Health/Medical Writers

MAYWOOD, N.J.--(BUSINESS WIRE)--July 24, 2003

The results of two surveys released by the American Legacy Foundation The American Legacy Foundation (ALF)[1][2][3] is a non-profit organization dedicated to preventing teen smoking and encouraging smokers to quit.  show that 65% of young women smokers want to quit but only 3% succeed. The American Legacy Foundation, an independent public health foundation dedicated to reducing tobacco use, based its results on two nationally representative surveys of young smokers.

"These results make it clear that quitting smoking is very difficult, regardless who the smoker is," said Dr. Michael Munzar, Medical Director of Nymox Pharmaceutical Corporation (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
: NYMX NYMX New York Mercantile Exchange ). "Effective smoking cessation smoking cessation Public health Temporary or permanent halting of habitual cigarette smoking; withdrawal therapies–eg, hypnosis, psychotherapy, group counseling, exposing smokers to Pts with terminal lung CA and nicotine chewing gum are often ineffective.  programs are an essential part of any tobacco control program aimed at curbing the tragic toll and rising healthcare costs levied by cigarettes and other tobacco products. We believe that our NicAlert(TM) product can be a valuable aid to any smoking cessation program by providing a quick, easy, point-of-care method of monitoring and verifying smoking cessation efforts. NicAlert(TM) can help customize therapy for quitting smoking."

NicAlert(TM) is a powerful one-step urine test for determining smoking and tobacco product exposure and use. NicAlert(TM) received clearance for medical use from the U.S. FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 in October 2002. NicAlert(TM) provides the capability of measuring cotinine cotinine (kō´tinēn),
n a substance that remains in body fluids after nicotine has been used. Presence of this chemical in body fluids is considered proof of recent nicotine use.
 levels in an easy-to-use, cost effective, rapid format. The NicAlert product does not require any instruments or special training for its use.

NicAlert(TM) can help smokers quit as shown by the results of a large European clinical trial which found significant smoking reduction over the four-month trial period when nicotine replacement therapy Nicotine replacement therapy
A method of weaning a smoker away from both nicotine and the oral fixation that accompanies a smoking habit by giving the smoker smaller and smaller doses of nicotine in the form of a patch or gum.
 (NRT NRT Nicotine Replacement Therapy
NRT Norm-Referenced Test
NRT near real time
NRT Non-Real-Time
NRT National Response Team
NRT Tokyo, Japan - Narita (Airport Code)
NRT Net Registered Tonnage
) was combined with individual cotinine levels as measured by NicAlert. The study of NRT with NicAlert(TM) was undertaken at the Hirslanden Lung Center Zurich, Switzerland. The lead investigator was Dr. Karl Klingler. Some results from this study were presented at the 75th anniversary of the Congress of Swiss Pneumologists in St. Gallen, Switzerland. Further results will be presented at the 12th World Conference on Tobacco or Health in Helsinki August 3-8, 2003.

NicAlert(TM) is being used as the official test agent in several smoking cessation programs to be offered by the American Respiratory Alliance. NicAlert(TM) has also been successfully used in quit- smoking contests sponsored by public health officials in Switzerland and Canada.

Two recent independent peer-reviewed studies found the technology employed in NicAlert(TM) to be an accurate, rapid and cost-effective means of confirming smoking status. One study, "Validating a Dipstick dipstick /dipĀ·stick/ (dipĀ“stik) a strip of cellulose chemically impregnated to render it sensitive to protein, glucose, or other substances in the urine.  Method for Detecting Recent Smoking," Cancer Epidemiology, Biomarkers & Prevention (2002; 11: 1123-1125) examined the smoking status of patients at a cancer clinic and found that the results obtained using Nymox's tobacco product exposure test had an "excellent agreement" with state-of-the-art sophisticated laboratory measurements but at a substantially lower cost (over 90% less). The second study, "The Accuracy of Self-Reported Smoking Status Assessed by Cotinine Test Strips," Nicotine & Tobacco Research (2002; 4: 305-9) found Nymox's product to be "an inexpensive and rapid method to routinely biochemically confirm smoking status at a clinical visit." The authors described the Nymox product as a "simple, inexpensive and rapid measure to immediately confirm smoking status in field settings."

The U.S. Surgeon General, the Centers for Disease Control and Prevention Centers for Disease Control and Prevention (CDC), agency of the U.S. Public Health Service since 1973, with headquarters in Atlanta; it was established in 1946 as the Communicable Disease Center.  (CDC See Control Data, century date change and Back Orifice.

CDC - Control Data Corporation
), the World Health Organization (WHO) and many other public health organizations have targeted tobacco use as the single most preventable cause of premature death today. The CDC estimates that smoking causes over 440,000 premature deaths annually in the United States and creates an economic loss of over $150 billion a year.

More information about Nymox is available at www.nymox.com, email: info@nymox.com, or 800-936-9669.

This press release contains certain "forward-looking statements" as defined in the United States Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995 that involve a number of risks and uncertainties. There can be no assurance that such statements will prove to be accurate and the actual results and future events could differ materially from management's current expectations. Such factors are detailed from time to time in Nymox's filings with the United States Securities and Exchange Commission and other regulatory authorities.
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Publication:Business Wire
Geographic Code:1CANA
Date:Jul 24, 2003
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