New Software for Agilent Bioanalyzer Features Unique RNA Quality Control, FDA Compliance Tools.PALO ALTO, Calif. -- Agilent Technologies Inc. (NYSE NYSE See: New York Stock Exchange :A) today introduced new software for the Agilent 2100 bioanalyzer that includes a unique RNA Integrity Number The RNA integrity number (RIN) is an algorithm for assigning integrity values to RNA measurements. The integrity of RNA is a major concern for gene expression studies and traditionally has been evaluated using the 28S to 18S rRNA ratio, a method that has been shown to be algorithm for RNA RNA: see nucleic acid. RNA in full ribonucleic acid One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic quality control and tools for compliance with FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. rule 21 CFR CFR See: Cost and Freight Part 11, which governs data security, access and electronic signatures. The Agilent 2100 bioanalyzer is a groundbreaking lab-on-chip electrophoresis and flow cytometry flow cytometry (flōˑ sī·t  ˑ·m analysis tool used for DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. , RNA, proteins and cells. "More than 800 customers have downloaded the RIN beta release, and a recent survey indicates that most of them found it very valuable in their work," said Tony Owen, marketing manager for Agilent's Life Science and Chemical Analysis. "This is the first time that RIN is available in a commercial package, and we anticipate strong demand." The assessment of RNA integrity is a critical first step in obtaining gene expression data. Agilent 2100 bioanalyzer expert software B.02.01 extracts information about RNA sample integrity from a bioanalyzer electrophoretic trace and generates an easy-to-interpret RIN. To facilitate use of RIN and the overall data analysis, a second-generation Result Flagging tool has been incorporated, letting users define rules to automatically color flag samples based on diverse criteria at the sample or even the individual sample peak level. The new 2100 bioanalyzer Security Pack provides productivity and compliance support features to address the data security, integrity and traceability requirements of FDA 21 CFR Part 11. The software offers result versioning and version management; user-independent, automatic audit trails; and electronic signing capabilities for electronic records. Access to the application is protected by mandatory logon with a user identification code and password. Electronic records generated by the application are always stored with all related raw, meta and result data. The software seamlessly integrates with the 2100 bioanalyzer expert software, which supports key Good Laboratory Practice requirements such as installation qualification and operational qualification. With the completion of the compliance suite the bioanalyzer is now the preferred alternative for pharmaceutical QC, replacing gel electrophoresis, which is labor intensive Labor Intensive A process or industry that requires large amounts of human effort to produce goods. Notes: A good example is the hospitality industry (hotels, restaurants, etc), they are considered to be very people-oriented. See also: Capital Intensive, Trading Dollars and relatively inaccurate and unreliable. About Agilent Technologies Agilent Technologies Inc. (NYSE:A) is the world's premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. The company's 28,000 employees serve customers in more than 110 countries. Agilent had net revenue of $7.2 billion in fiscal year 2004. Information about Agilent is available on the Web at www.agilent.com. NOTE TO EDITORS: Press releases, photography and other information can be accessed on the Agilent Life Sciences and Chemical Analysis newsroom at www.agilent.com/about/newsroom/lsca. Further technology, corporate citizenship Corporate Citizenship The extent to which businesses are socially responsible in meeting legal, ethical and economic responsibilities placed on them by shareholders. The aim it to create higher standards of living and quality of life in the community in which it operates, while and executive news is available on the Agilent news site at www.agilent.com/go/news. |
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