New Protective Groups Now Available To the Synthetic Organic Chemist, Such As the Uniquely Removable 2-Methoxybenzenesulfonyl Group for the Protection of Amines Is Now Available In A 4th Edition Book.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c46183) has announced the addition of Greenes Protective Groups in Organic Synthesis Organic synthesis is the construction of organic molecules via chemical processes. Organic molecules can often contain a higher level of complexity compared to purely inorganic compounds, so the synthesis of organic compounds has developed into one of the most important aspects of , 4th Edition to their offering. The Most Comprehensive Guide to Protective Groups in Organic Synthesis Currently Available For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal chemists who want to control the reactivity of the most common functional groups during a synthetic sequence. The Fourth Edition includes significant developments in protective group chemistry since 1998. In addition to incorporating new protective groups now available to the synthetic organic chemist, such as the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines amines (  mēnz´),n.pl organic compounds that contain nitrogen. , the book also covers new techniques for the formation and cleavage of existing protective groups, providing the most relevant and useful examples to illustrate each methodology. The content is organized around the functional group to be protected (ethers, acids, carbonyl groups, amines, amides, phenols phenols (fēˑ·n  lz),n. , etc.), and ranges from the simplest to the most complex highly specialized protective groups. New features of the Fourth Edition include: * The addition of numerous new protective groups, such as the fluorous family * New methods for the cleavage and introduction of many of the classic protective groups highlighting selectivity issues when reported in the literature * Expanded coverage of the unexpected side reactions that occur with protective groups * A new chart covering the selective deprotection of silyl ethers * 3,100 new references from the professional literature, complete through the end of 2005 Author information Peter G. M. Wuts, PHD, is a Senior Research Fellow at Pfizer in Ann Arbor, Michigan  “Ann Arbor” redirects here. For other uses, see Ann Arbor (disambiguation). Ann Arbor is a city in the U.S. state of Michigan and the county seat of Washtenaw County. . The late Theodora W. Greene, PHD, was the librarian for the Rowland Institute for Science The Rowland Institute for Science was founded by Edwin H. Land, founder of Polaroid Corporation, as a nonprofit basic research organization in 1980. The Rowland, as it is commonly referred to, is dedicated to experimental science across a wide range of disciplines. and former assistant editor for Organic Syntheses Organic Syntheses is a scientific journal that since 1921 has provided the chemistry community with annual collections of detailed and checked procedures for the organic synthesis of organic compounds. . Content Outline: * Preface to the Fourth Edition. * Preface to the Third Edition. * Preface to the Second Edition. * Preface to the First Edition. Abbreviations. * 1. The Role of Protective Groups in Organic Synthesis. * 2. Protection for the Hydroxyl Group hydroxyl group (hīdrŏk`sĭl), in chemistry, functional group that consists of an oxygen atom joined by a single bond to a hydrogen atom. An alcohol is formed when a hydroxyl group is joined by a single bond to an alkyl group or aryl group. , Including 1,2- and 1,3-Diols. * 3. Protection for Phenols and Catechols. * 4. Protection for the Carbonyl Group. * 5. Protection for the Carboxyl Group. * 6. Protection for the Thiol thiol: see mercaptan. Group. * 7. Protection for the Amino Group. * 8. Protection for the Alkyne alkyne (ăl`kīn), any of a group of aliphatic hydrocarbons whose molecules contain one or more carbon-carbon triple bonds (see chemical bond). Alkynes with one triple bond have the general formula CnH2n−2. CoCH. * 9. Protection for the Phosphate Group. * 10. Reactivities, Reagents, and Reactivity Charts. Reactivity Charts. * 1 Protection for the Hydroxyl Group: Ethers. * 2 Protection for the Hydroxyl Group: Esters. * 3 Protection for 1,2- and 1,3-Diols. * 4 Protection for Phenols and Catechols. * 5 Protection for the Carbonyl Group. * 6 Protection for the Carboxyl Group. * 7 Protection for the Thiol Group. * 8 Protection for the Amino Group: Carbamates carbamates effective insecticides which exert their effect by temporarily inhibiting cholinesterase activity. They are also capable of poisoning. Clinical signs are pupillary constriction, muscle tremor, salivation, ataxia and dyspnea. . * 9 Protection for the Amino Group: Amides. * 10 Protection for the Amino Group: Special CoNH Protective Groups. * 11 Selective Deprotection of Silyl Ethers. * Index. For more information visit http://www.researchandmarkets.com/reports/c46183 |
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