New Lower LDL Cholesterol Guidelines for Patients at Risk for Heart Disease Highlight Need for More Accurate Cholesterol Test Technology.BIRMINGHAM Birmingham, cities, United States Birmingham (bûr`mĭnghăm') 1 City (1990 pop. 265,968), seat of Jefferson co., N central Ala., in the Jones Valley near the southern end of the Appalachian system; founded and inc. , Ala ALA aminolevulinic acid. Ala alanine. ala (a´lah) pl. a´lae [L.] a winglike process. . -- Atherotech's Comprehensive VAP (Value Added Process) An executable program in a NetWare 2.x server. Starting with NetWare 3.x, VAPs were replaced by NLMs. See NetWare. (TM) Cholesterol Test Cholesterol Test Definition The cholesterol test is a quantitative analysis of the cholesterol levels in a sample of the patient's blood. Total serum cholesterol (TC) is the measurement routinely taken. Significantly Improves LDL Cholesterol LDL cholesterol n. See low-density lipoprotein. LDL Cholesterol Low-density lipoprotein cholesterol is the primary cholesterol molecule. High levels of LDL increase the risk of coronary heart disease. Risk Assessment
What: An important update to National Cholesterol Education
Program (NCEP) clinical guidelines released this week
establishes lower LDL (low-density lipoprotein)
cholesterol goals for patients at high risk for heart
disease -- highlighting the need for more accurate
cholesterol test technology. A growing body of scientific
evidence indicates that routine cholesterol tests, which
calculate rather than directly measure LDL (the "bad"
cholesterol), may provide inaccurate LDL measurements,
especially at the low LDL levels recommended in the
guidelines. In contrast, the next-generation VAP (Vertical
Auto Profile) Cholesterol Test provides the more accurate,
direct-measured LDL required to effectively assess and
treat heart disease risk. The NCEP is coordinated by the
National Heart, Lung, and Blood Institute of the National
Institutes of Health.
How: The VAP Cholesterol Test provides direct, detailed
measurements of LDL cholesterol, improving on routine
calculated values, and includes atherogenic LDL subclasses
Lp(a), intermediate-density lipoprotein (IDL), and the
emerging risk factor known as LDL cholesterol size
pattern. Recognized by the NCEP as playing important roles
in the development of heart disease, these measurements
previously were unavailable in a single cholesterol test.
Developed by Birmingham, Ala.-based Atherotech, the
affordable VAP Test is available nationwide through
leading national and regional reference laboratories and
is reimbursed by Medicare and most insurance carriers.
Why: With cardiovascular diseases such as heart disease killing
nearly 1 million people annually, the NIH says Americans
need to act now to prevent future heart attacks. The
NCEP's updated clinical practice guidelines advise
physicians to consider more intensive treatment for
patients at high and moderately high risk for a heart
attack. Specifically, the new guidelines suggest lower
treatment goals for LDL cholesterol in high- and
moderate-risk patients, and provide a therapeutic option
to initiate cholesterol-lowering drugs at lower LDL
thresholds. For patients at very high risk, such as those
who have heart disease and multiple risk factors, the
guidelines recommend an LDL of less than 70. Calculated
LDL provided by routine cholesterol tests, however, may
underestimate LDL by up to 20 percent, especially at
lower LDL levels -- possibly providing a false sense of
security for some patients and their physicians. With the
national availability of the VAP Test, physicians now have
access to a fast, accurate, easy-to-use, and affordable
method to obtain the accurate LDL readings that are vital
for high-risk patients.
Who: Atherotech is a pioneer in cardiodiagnostic technology.
The company's VAP Cholesterol Test recently was named one
of "Five Tests Worth Paying For" by The Wall Street
Journal.
Where: Consumers interested in the VAP Cholesterol test should
speak with their doctors or visit www.thevaptest.com.
Direct access to the VAP Test also is available at
www.getavap.com.
Interviews: Richard Lanman, M.D., Atherotech's chief medical officer,
is available to discuss the new NCEP guidelines update and
the importance of obtaining accurate LDL cholesterol
readings. To schedule an interview, contact Barbara
Sullivan at Sullivan & Associates, (714) 374-6174.
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