New HIV Drugs: Extensive List, Additional Information.The most complete recent list we have seen of anti-HIV drugs in development -- over 60 total, including the approved drugs In the United States, the FDA approves drugs. Before a drug can be prescribed, it must undergo an extensive FDA approval process. This process involves first testing the drug on animals or in medical labs. -- was posted recently by Ben Cheng of Project Inform, on the Web site of the new AIDS Treatment Activist Coalition. The list, at http://www.atac-usa.org/RDACommittee.html (scroll down, or click on "Chart on drugs in development", has the generic or chemical name of each compound, the class of drug (nucleoside nucleoside Any of a class of organic compounds, including structural subunits of nucleic acids. Each consists of a molecule of a five-carbon sugar (ribose in RNA, deoxyribose in DNA) and a nitrogen-containing base, either a purine or a pyrimidine. analog, protease inhibitor protease inhibitor (prō`tē-ās'), any of a class of drugs that interfere with replication of the AIDS virus (HIV), by blocking an enzyme (protease) necessary in the late stages of its reproduction. , etc.), the phase of development (preclinical preclinical /pre·clin·i·cal/ (-klin´i-k'l) before a disease becomes clinically recognizable. pre·clin·i·cal adj. 1. , phase I, phase II, phase III Noun 1. phase III - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA or approved), and the pharmaceutical company doing the work. For another extensive list of drugs in (or formerly in) development, see the Treatment Action Group (TAG) Web site: http://www.aidsinfonyc.org/tag/science/pipeline.html. For more information about some of the more prominent new drugs currently being researched, see "New Agents for Anti-HIV Therapy," by Joseph J. Eron Jr., M.D., and Robert L. Murphy, M.D. It is available on the Medscape site, http://hiv.medscape.com (click on 'New Agents for Anti-HIV Therapy' if this link is still there, or search the site for the author's last name, and look for the title in the results returned). Note: The Medscape site requires registration, but registration is free, and it need be done only once (provided you remember the user ID and password you choose). Most articles on continuing-education medical sites remain online for one year. |
|
||||||||||||||||||||
Printer friendly
Cite/link
Email
Feedback
Reader Opinion