National Institute of Radiological Sciences Confirms PET Imaging is Useful in Antipsychotic Dosage Selection.Tokyo, Japan, Feb 1, 2006 - (JCN JCN Japan Corporate News
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JCN joint communications network (US DoD) ) - The National Institute of Radiological Science (NIRS NIRS Near Infrared Spectroscopy
NIRS Nuclear Information and Resource Service
NIRS Near-Infrared Reflectance Spectroscopy
NIRS National Institute of Radiological Science
NIRS National Information and Reporting System
NIRS National Informatics Recognition System ) announced on January 30 that it has confirmed the utility of positron-emission tomography (PET) imaging in determining the optimal dosage of antipsycotics.
Specifically, the NIRS has reevaluated the clinical dosages of two antipsychotics Antipsychotics
A class of drugs used to control psychotic symptoms in patients with psychotic disorders such as schizophrenia and delusional disorder. Antipsychotics include risperidone (Risperdal), haloperidol (Haldol), and chlorpromazine (Thorazine). sulpiride and sultopride using PET imaging. Currently, the optimal dosages of sulpiride and sultopride are set at 300-600mg per day.
The reevaluation results shows that the optimal dosage of sultpiride is up to 1010-1730 mg per day, higher than the currently prescribed amount. Meanwhile, sultopride can exert beneficial effects with only 20-30mg per day.
Details of these findings will be soon available in the International Journal of Neuropsychopharmacology. Going forward, the NIRS plans to conduct research targeting schizophrenic schiz·o·phren·ic
Of, relating to, or affected by schizophrenia.
One who is affected with schizophrenia. patients.
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