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Nandrolone (Deca Durabolin) disappears in U.S., generic may return in July.


In late May or early June treatment activists learned that the only version of nandrolone nandrolone /nan·dro·lone/ (nan´dro-lon) an anabolic steroid with lesser androgenic effects; used as n. decanoate and n.  currently available in the U.S. (brand name Deca Durabolin) was being discontinued. Soon we started hearing from patients whose pharmacies told them they could not find the drug. Nandrolone is approved for anemia due to renal insufficiency renal insufficiency A defect in renal ability to 'clear' waste products, a sign of inadequate glomerular filtration , but many doctors use it off label for AIDS wasting. (1,2,3) Usually the patients, doctors, and pharmacists had heard nothing about the drug going away. It just disappeared from the supply chain.

Nandrolone remains available in other countries. But because it is a controlled substance controlled substance n. a drug which has been declared by federal or state law to be illegal for sale or use, but may be dispensed under a physician's prescription.  due to abuse by body builders, patients cannot import those products for personal use. Until three years ago there were lower-cost generic nandrolone products available in the U.S. Then they also disappeared with little notice.

Other anabolics that had also been used off label in AIDS have been discontinued -- and then later come back with an HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States.  label (FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 approval for the HIV use), but with a huge price increase, typically more than 10 times their former cost. We do not know if that will happen with nandrolone.

Activists have investigated and been told that a new generic nandrolone will be available after the July 4 weekend. But what we have heard so far is confusing and contradictory.

Recently we heard that a compounded version of nandrolone is available now.

Because the situation is unclear and rapidly changing, check Web sites of organizations that have been following this issue, including http://www.houstonbuyersclub.com, http://www.atac-usa.org, and http://www.medibolics.com for the latest information.

References

(1.) Sattler FR, Jaque SV, Schroeder ET, and others. Effects of pharmacological doses of nandrolone decanoate nandrolone decanoate Endocrinology A long-acting parenteral 17β-hydroxyl ester of 19-nortestosterone with weak androgenic activity, used as an androgen–eg, for refractory anemia. Cf Androgen replacement therapy.  and progressive resistance training in immunodeficient patients infected with human immunodeficiency virus human immunodeficiency virus
n.
HIV.


Human immunodeficiency virus (HIV)
A transmissible retrovirus that causes AIDS in humans.
. Journal of Clinical Endocrinology and Metabolism. April 1999; volume 84, number 4, pages 1268-1276.

(2.) Strawford A, Barbieri T, Neese R, and others. Effects of nandrolone decanoate therapy in borderline hypogonadal men with HIV-associated weight loss. Journal of Acquired Immune Deficiency Syndromes Acquired immune deficiency syndrome (AIDS)

A viral disease of humans caused by the human immunodeficiency virus (HIV), which attacks and compromises the body's immune system.
 and Human Retrovirology. Feb. 1999; volume 20, number 2, pages 137-46.

(3.) Gold J, High HA, Li Y, and others. Safety and efficacy of nandrolone decanoate for treatment of wasting in patients with HIV infection. AIDS. June 1996; volume 10, number 7, pages 745-52.
COPYRIGHT 2002 John S. James
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2002, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Article Details
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Author:James, John S.
Publication:AIDS Treatment News
Article Type:Brief Article
Date:Jun 28, 2002
Words:383
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