NSAIDS and Fosamax are a bad brew.
In a study from Baylor College of Medicine, 26 healthy volunteers were randomly assigned to take Fosamax, naproxen, or both drugs together for 10 days, and then were evaluated by endoscopy for evidence of gastric ulcers. Gastric ulcers occurred in eight percent of those taking Fosamax, in 12% of those taking only naproxen, but in 38% of those taking both drugs.
Over 10 million Americans have osteoporosis and another 18 million are at risk due to low bone density Although running is protective to some extent against osteoporosis, overtraining can have the opposite effect when it is part of the Female Athlete Triad in which low estrogen levels can decrease bone density in premenopausal women. To be safe, always be sure to discuss all medications and your lifestyle with your doctor or pharmacist.
(Archives of Internal Medicine, 2000. Vol. 160, No. 5, pp. 705-708; NIH Consensus Statement 111, Osteoporosis, Prevention, Diagnosis and Therapy)
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|Title Annotation:||gastric ulcer risk|
|Publication:||Running & FitNews|
|Article Type:||Brief Article|
|Date:||Feb 1, 2002|
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