NCCN Updates Antiemesis Guidelines.JENKINTOWN, Pa. -- The National Comprehensive Cancer Network (NCCN) is pleased to announce updates to the NCCN Antiemesis Guidelines. The NCCN Clinical Practice Guidelines clinical practice guidelines Clinical policies, practice guidelines, practice parameters, practice policies Medtalk Systematically developed statements to assist practitioner and Pt decisions about appropriate health care for specific clinical circumstances. See Psychology. in Oncology[TM] are used extensively by managed care companies and by Medicare as the basis for coverage policies. The guidelines have a new recommendation for breakthrough treatment for chemotherapy-induced nausea/vomiting. Nabilone (Cesamet, Valeant) is now recommended for breakthrough treatment. The guidelines table describing the emetogenic potential of different antineoplastic agents has been revised. Bortezomib (Velcade, Millennium), dasatinib (Sprycel, Bristol Myers-Squibb), decitabine (Dacogen, MGI Pharma), lenalidomide (Revlimid, Celgene), nelarabine (Arranon, GlaxoSmithKline), sorafenib (Nexavar, Bayer Pharmaceuticals), sunitinib (Sutent, Pfizer), thalidomide (Thalomid, Celgene), and trastuzumab (Herceptin, Genentech) are all now considered to have minimal emetic emetic (əmĕt`ĭk), substance that produces vomiting. Direct, or gastric, emetics, which act directly on the stomach, include syrup of ipecac, sulfate of zinc or copper, alum, ammonium carbonate, mustard in water, or copious quantities of risk. Metoclopramide (Reglan, Baxter) and diphenhydramine diphenhydramine /di·phen·hy·dra·mine/ (di?fen-hi´drah-men) a potent antihistamine, used as the hydrochloride salt in the treatment of allergic symptoms and for its anticholinergic, antitussive, antiemetic, antivertigo, and antidyskinetic (Benadryl, Parke Davis) are no longer recommended for delayed emesis emesis /em·e·sis/ (em´e-sis) vomiting. em·e·sis n. pl. em·e·ses The act or process of vomiting. Emesis The medical term for vomiting. prevention for patients receiving moderate-emetic-risk chemotherapy. NCCN Clinical Practice Guidelines in Oncology(TM) are developed and updated through a consensus-driven process with explicit review of the scientific evidence by multidisciplinary panels of expert physicians from NCCN member institutions. The most recent version of this and all the guidelines are available free of charge at www.nccn.org. About the National Comprehensive Cancer Network The National Comprehensive Cancer Network (NCCN), a not-for-profit alliance of 20 of the world's leading cancer centers, is dedicated to improving the quality and effectiveness of care provided to patients with cancer. Through the leadership and expertise of clinical professionals at NCCN member institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system. As the arbiter of high-quality cancer care, NCCN promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers. The primary goal of all NCCN initiatives is to improve the quality, effectiveness, and efficiency of oncology practice so patients can live better lives. The NCCN member institutions are: City of Hope Cancer Center, Los Angeles, CA; Dana-Farber/Brigham & Women's Cancer Center | Massachusetts General Hospital Massachusetts General Hospital Health care The major teaching hospital for Harvard Medical School, widely regarded as one of the best health care centers in the world Cancer Center, Boston, MA; Duke Comprehensive Cancer Center, Durham, NC; Fox Chase Cancer Center The Fox Chase Cancer Center is a medical research facility and hospital located in the northeast section of Philadelphia, Pennsylvania, United States. The Center is an independent, non-profit institution which specializes in the treatment and prevention of cancer. , Philadelphia, PA; Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT; Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance, Seattle, WA; Arthur G. James Cancer Hospital & Richard J. Solove Research Institute at The Ohio State University, Columbus, OH; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL; Memorial Sloan-Kettering Cancer Center The Memorial Sloan-Kettering Cancer Center (MSKCC) in New York City is a cancer treatment and research institution founded in 1884 as the New York Cancer Hospital. The main campus is located at 1275 York Avenue, between 67th and 68th Streets, with other locations in New , New York, NY; H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida • • [ , Tampa, FL; Roswell Park Cancer Institute The Roswell Park Cancer Institute is a cancer research and treatment center located in Buffalo, New York. Founded in 1898 by Dr. Roswell Park, it was the first dedicated medical facility for cancer treatment and research in the United States. , Buffalo, NY; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine Washington University School of Medicine, located in St. Louis, Missouri, is one of the most competitive and highly regarded medical schools and biomedical research institutes in the United States. , St. Louis, MO; St. Jude Children's Research Hospital/University of Tennessee Cancer Institute, Memphis, TN; Stanford Comprehensive Cancer Center, Stanford, CA; University of Alabama at Birmingham UAB began in 1936 as the Birmingham Extension Center of the University of Alabama. Because of the rapid growth of the Birmingham area, it was decided that an extension program for students who had difficulties which prevented them from studying in Tuscaloosa was needed. Comprehensive Cancer Center, Birmingham, AL; UCSF Comprehensive Cancer Center, San Francisco, CA; University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; UNMC Eppley Cancer Center at The Nebraska Medical Center, Omaha, NE; and The University of Texas M. D. Anderson Cancer Center, Houston, TX. For more information, visit www.nccn.org. |
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