Multispan and Promega to Streamline GPCR Drug Screening Programs.MADISON, Wis. -- Today Multispan and Promega agreed to co-develop assay tools for G-protein coupled receptor (GPCR GPCR Guanine Nucleotide-Binding Protein-Coupled Receptor
GPCR GTP-binding Protein-Coupled Receptor ) screening. The companies will combine Multispan GPCR cell lines and Promega bioluminescent bi·o·lu·mi·nes·cence
Emission of visible light by living organisms such as the firefly and various fish, fungi, and bacteria.
bi technologies to create novel optimized GPCR screening protocols. The first tools will support cell lines and cAMP-Glo[TM] Assay for quantification of signal. Additional tools will be developed for cell-based assay detection.
This combination of validated biologic components with the most sensitive and dynamic luminescence luminescence, general term applied to all forms of cool light, i.e., light emitted by sources other than a hot, incandescent body, such as a black body radiator. assay detection technology for high-throughput screening High-throughput screening (HTS), is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry. Purpose and method will provide increased speed and efficiency in GPCR drug screening. Multispan is a leading supplier of high quality GPCR tools; Promega is the premier supplier of bioluminescent cell-based assay technologies for drug screening.
"Pre-optimized protocols will reduce assay development times, from months to days, helping deliver better GPCR targeted drugs faster," according to according to
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"Partnering with Promega further broadens the application of Multispan's strong GPCR cell biology expertise. The combined offering from the two companies will benefit our customers enormously in drug discovery," said Dr. Helena Mancebo, President & CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Multispan.
The companies are planning joint scientific presentations and publications demonstrating the applications of the validated tools for GPCR drug discovery.
Multispan Inc. is a San Francisco Bay San Francisco Bay, 50 mi (80 km) long and from 3 to 13 mi (4.8–21 km) wide, W Calif.; entered through the Golden Gate, a strait between two peninsulas. Area-based biotechnology company focused exclusively on GPCRs, the most important protein class of therapeutic targets. Privately held, and founded in 2004, Multispan has created the industry's largest collection of human GPCR clones and has engineered a large collection of GPCR-expressing cell lines, including the proprietary HEx[TM] series of High Expression cell lines. Multispan also offers custom services in compound profiling, antibody generation and cell line development. For more information about Multispan, visit www.multispaninc.com.
Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company's 2000 products enable scientists worldwide to advance their knowledge in genomics, proteomics, cellular analysis, molecular diagnostics and human identification. Founded in 1978, the company is headquartered in Madison, WI, USA with branches in twelve countries and 54 global distributors. Annual sales exceed $220 million. For more information about Promega, visit www.promega.com.