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Multi-drug resistant TB may be widespread.

The global epidemic of multi-drug resistant tuberculosis may be larger than thought, according to according to
1. As stated or indicated by; on the authority of: according to historians.

2. In keeping with: according to instructions.

 a recent article in the Lancet.

The study found anti-TB drug resistance in virtually all of the 79 countries surveyed, with particularly high levels in the former Soviet Union and China.

About a third of the world's population is infected in·fect  
tr.v. in·fect·ed, in·fect·ing, in·fects
1. To contaminate with a pathogenic microorganism or agent.

2. To communicate a pathogen or disease to.

3. To invade and produce infection in.
 with Mycobacterium tuberculosis Mycobacterium tuberculosis
Tubercic bacillus.

Mycobacterium tuberculosis
 and 8.9 million people develop the disease each year. In 2004, 1.7 million people died from the disease. The emergence of strains that are resistant to the two most potent anti-TB drugs is linked to wide misuse of antimicrobials, the study noted.

The study, published Dec. 16, estimated 424,000 cases of multi-drug resistant TB emerged worldwide in 2004. China, India and Russia accounted for more than half of those cases. The study's authors found decreasing trends of the disease in the United States United States, officially United States of America, republic (2005 est. pop. 295,734,000), 3,539,227 sq mi (9,166,598 sq km), North America. The United States is the world's third largest country in population and the fourth largest country in area. , Hong Kong Hong Kong (hŏng kŏng), Mandarin Xianggang, special administrative region of China, formerly a British crown colony (2005 est. pop. 6,899,000), land area 422 sq mi (1,092 sq km), adjacent to Guangdong prov.  and Cuba.

The researchers noted that despite the work of the Global Project on Anti-Tuberculosis Drug Resistance Surveillance, which was established in 1994, "there remain important gaps in data from many countries with the highest burden of tuberculosis, areas where the HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States.  epidemic is fueling the tuberculosis epidemic, and countries where prevalence of drug resistance is expected to be high because of historically poor tuberculosis control." The authors also noted that one of the main obstacles to expanded surveillance is the lack of functioning laboratory networks.
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Title Annotation:GLOBE IN BRIEF; Tuberculosis
Author:Arias, Donya C.
Publication:The Nation's Health
Article Type:Brief article
Geographic Code:1USA
Date:Feb 1, 2007
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